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IL-1 beta Proteins

(Interleukin 1, beta (IL1B))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].
IL-1 beta Protein (AA 117-269) (His-Avi Tag) IL-1 beta Protein (AA 117-269) (His-Avi Tag) IL-1 beta Protein (AA 117-269) (His-Avi Tag) (ABIN7274882)

IL1B Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC

IL-1 beta Protein (AA 117-269) (His-Avi Tag,Biotin) IL-1 beta Protein (AA 117-269) (His-Avi Tag,Biotin) IL-1 beta Protein (AA 117-269) (His-Avi Tag,Biotin) (ABIN7274883)

IL1B Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

IL-1 beta Protein (AA 1-269) (GST tag) IL-1 beta Protein (AA 1-269) (GST tag) IL-1 beta Protein (AA 1-269) (GST tag) (ABIN1307738)

IL1B Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

IL-1 beta Proteins by Grade

Find IL-1 beta Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

IL-1 beta Proteins by Origin

Find IL-1 beta Proteins for a variety of species such as anti-Human IL-1 beta, anti-Mouse IL-1 beta, anti-Rat IL-1 beta. The species listed below are among those available. Click on a link to go to the corresponding products.

IL-1 beta Proteins by Source

Here you will find IL-1 beta Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

IL-1 beta Proteins by Protein Type

Here you can find IL-1 beta Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

IL-1 beta Proteins by Application

Find IL-1 beta Proteins validated for a specific application such as WB, ELISA, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

IL-1 beta Proteins by Biological Activity

Find IL-1 beta Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular IL-1 beta Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (5)
Cat. No. ABIN7274882
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (4)
Cat. No. ABIN7274883
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1307738
Quantity 10 μg
Datasheet Datasheet
Reactivity Pig
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123535
Quantity 50 μg
Datasheet Datasheet
Reactivity Horse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123532
Quantity 50 μg
Datasheet Datasheet
Reactivity Goat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123530
Quantity 50 μg
Datasheet Datasheet
Reactivity Dog
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123529
Quantity 50 μg
Datasheet Datasheet
Reactivity Chicken
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123528
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5855196
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307742
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964158
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7320465
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7321252
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN6239741
Quantity 50 μg
Datasheet Datasheet
Reactivity Sheep
Source Yeast
Validations
  • (2)
Cat. No. ABIN7479109
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IL-1 beta Proteins

Shao, Fang, Dang, Xue, Zhang, Li, Qiao, Cao, Zhuang, Shen, Zhang, Qiao, Li, Gudjonsson, Wang: "Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk." in: Frontiers in immunology, Vol. 10, pp. 746, (2020) (PubMed).

Luo, Huang, He, Liu, Chen, Liu, Mi, Li, Sun, Li, Xiang, Su: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).

Hollborn, Vogler, Reichenbach, Wiedemann, Bringmann, Kohen: "Regulation of the hyperosmotic induction of aquaporin 5 and VEGF in retinal pigment epithelial cells: involvement of NFAT5." in: Molecular vision, Vol. 21, pp. 360-77, (2015) (PubMed).

Ubertini, Norelli, DArcangelo, Gurtner, Cesareo, Baldari, Gentileschi, Piaggio, Nisticò, Soddu, Facchiano, Bossi: "Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist." in: Oncogene, Vol. 34, Issue 19, pp. 2493-504, (2015) (PubMed).

von Burg, Chappaz, Baerenwaldt, Horvath, Bose Dasgupta, Ashok, Pieters, Tacchini-Cottier, Rolink, Acha-Orbea, Finke: "Activated group 3 innate lymphoid cells promote T-cell-mediated immune responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 35, pp. 12835-40, (2014) (PubMed).

Nikolakopoulou, Dutta, Chen, Miller, Trapp: "Activated microglia enhance neurogenesis via trypsinogen secretion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 21, pp. 8714-9, (2013) (PubMed).

Kahlenberg, Thacker, Berthier, Cohen, Kretzler, Kaplan: "Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 6143-56, (2011) (PubMed).

Zhang, Bennett, Verkman: "Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms." in: Annals of neurology, Vol. 70, Issue 6, pp. 943-54, (2011) (PubMed).

Tiwari, Wang, Brochetta, Ke, Vita, Qi, Rivera, Soranzo, Zabucchi, Hong, Blank: "VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways." in: Blood, Vol. 111, Issue 7, pp. 3665-74, (2008) (PubMed).

Yang, Poon, Luo, Cheung, Ho, Lo, Fan: "Up-regulation of vascular endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 4, pp. 2507-15, (2004) (PubMed).

Aliases for IL-1 beta Proteins

interleukin 1 beta (IL1B) Proteins
interleukin 1, beta (IL1B) Proteins
interleukin 1, beta (il1b) Proteins
interleukin 1 beta (Il1b) Proteins
IL-1 Proteins
IL-1 beta Proteins
IL-1B Proteins
Il-1b Proteins
IL-1b Proteins
IL-1BETA Proteins
IL-1beta Proteins
il1-b Proteins
IL1-BETA Proteins
IL1B Proteins
IL1beta Proteins
IL1F2 Proteins
zgc:111873 Proteins
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