IGLL1 Products
(Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
Categories
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured IGLL1 Categories
IGLL1 Antibodies
High quality antibodies with extensive validation data.
IGLL1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IGLL1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (4)
Cat. No.
ABIN516975
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (4)
Cat. No.
ABIN2118554
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN516973
Quantity
50 μg
Datasheet
Datasheet
Recommended IGLL1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307605
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3081886
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3133260
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our IGLL1 products
: "VpreB1/VpreB2/lambda 5 triple-deficient mice show impaired B cell development but functional allelic exclusion of the IgH locus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 12, pp. 6286-93, (2002) (PubMed).: "The identification of a nonclassical cadherin expressed during B cell development and its interaction with surrogate light chain." in: The Journal of biological chemistry, Vol. 275, Issue 40, pp. 31134-44, (2000) (PubMed).
: "Review article: role of the surrogate light chain and the pre-B-cell receptor in mouse B-cell development." in: Immunology, Vol. 101, Issue 4, pp. 435-41, (2000) (PubMed).
: "Repertoire selection by pre-B-cell receptors and B-cell receptors, and genetic control of B-cell development from immature to mature B cells." in: Immunological reviews, Vol. 175, pp. 33-46, (2000) (PubMed).
: "Antigen receptor engagement turns off the V(D)J recombination machinery in human tonsil B cells." in: The Journal of experimental medicine, Vol. 188, Issue 4, pp. 765-72, (1998) (PubMed).
: "IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development." in: International immunology, Vol. 6, Issue 8, pp. 1257-64, (1995) (PubMed).
: "Precursor B cells of mouse bone marrow express two different complexes with the surrogate light chain on the surface." in: European journal of immunology, Vol. 25, Issue 2, pp. 446-50, (1995) (PubMed).
: "The expression of Vpre-B/lambda 5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice." in: Cell, Vol. 77, Issue 1, pp. 133-43, (1994) (PubMed).
: "A complex of glycoproteins is associated with VpreB/lambda 5 surrogate light chain on the surface of mu heavy chain-negative early precursor B cell lines." in: The Journal of experimental medicine, Vol. 178, Issue 2, pp. 469-78, (1993) (PubMed).
Synonyms and alternative names related to IGLL1
immunoglobulin lambda like polypeptide 1 (IGLL1), immunoglobulin lambda-like polypeptide 1 (IGLL1), immunoglobulin lambda-like polypeptide 1 (Igll1), 14.1, AGM2, BB139905, CD179b, Igl-5, IGL1, IGL5, IGLJ14.1, IGLL, Igll, IGLL1, Igll1, IGLV, IGO, IGVPB, Lambda5, MGC151892, VPREB2Protein level used designations for IGLL1
- CD179 antigen-like family member B
- CD179b antigen
- Pre-B lymphocyte-specific protein-2
- ig lambda-5
- immunoglobulin omega polypeptide chain
- immunoglobulin-related 14.1 protein
- immunoglobulin-related protein 14.1
- lambda5
- Ig lambda chain V-1 region
- Ig light chain variable region
- immunoglobulin lambda-like polypeptide 1
- Lambda5
- Immunoglobulin lambda-like polypeptide 1-like
- immunoglobulin lambda chain 5
- lambda 5
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