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Study showed that Ndel1 (show NDEL1 Antibodies) enzyme activity is a complex trait influenced by many different genetic variants that may contribute to schizophrenia physiopathology
This study observed a significantly increased myelin basic protein (MBP (show MBP Antibodies)) and nuclear distribution protein nudE-like 1 (NDEL1 (show NDEL1 Antibodies)) mRNA levels in FEP patients compared with controls.
study provided comprehensive documentation of the expression patterns of Nde1 and Ndel1 (show NDEL1 Antibodies) in cultured cells as well as in mouse and human brains, and also highlighting that dosage effects of these two proteins might contribute to some cases of mental disorder
The Plasma Ndel1 (show NDEL1 Antibodies) enzyme activity is reduced in patients with schizophrenia.
Short (DISC)1 (show DISC1 Antibodies) splice variants show reduced or no binding to nudE nuclear distribution E homolog (NDEL)1 (show NDEL1 Antibodies) and phosphodiesterase (PDE (show ALDH7A1 Antibodies))4B proteins, but fully interact with FEZ1 (show LZTS1 Antibodies) and glycogen synthase kinase 3 (GSK3)beta (show GSK3b Antibodies).
Nudel (show NDEL1 Antibodies) markedly promotes the HSPC300 (show BRK1 Antibodies)-WAVE2 (show WASF2 Antibodies) interaction.
analysis of mixed NDE1-NDEL1 (show NDEL1 Antibodies) complexes demonstrates that NDE1 and NDEL1 (show NDEL1 Antibodies) can interact directly.
Cytosolic mfGbeta is recruited to dynein by Nudel (show NDEL1 Antibodies) and transported to the centrosome for rapid sequestration and degradation.
Studies indicate that binding of dynactin (show DCTN1 Antibodies), LIS1 (show PAFAH1B1 Antibodies) and NudEL (show NDEL1 Antibodies) regulate cytoplasmic dynein (show DYNC1H1 Antibodies) motor activity.
DISC1 (show DISC1 Antibodies) forms octamers via dimers as building blocks. S704C forms higher-order oligomers, without affecting its affinity with NDEL1 (show NDEL1 Antibodies)
This gene encodes a coiled-coil protein that plays a role in multiple processes including cytoskeletal organization, cell signaling and neuron migration, outgrowth and maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome X.
, mitosin-associated protein 1
, mitosin-associated protein MITAP1
, nuclear distribution protein nudE-like 1
, nudE nuclear distribution E homolog-like 1
, nudE nuclear distribution gene E homolog-like 1
, protein Nudel