Browse our anti-Integrin beta 3 (ITGB3) Antibodies

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anti-Integrin beta 3 Antibodies (ITGB3)
On are 686 Integrin beta 3 (ITGB3) Antibodies from 37 different suppliers available. Additionally we are shipping Integrin beta 3 Kits (24) and Integrin beta 3 Proteins (10) and many more products for this protein. A total of 735 Integrin beta 3 products are currently listed.
BDPLT2, BDPLT16, CD61, GP3A, GPIIIA, GT, INGRB3, INTB3, integrin
list all antibodies Gene Name GeneID UniProt
ITGB3 16416 O54890
Anti-Rat ITGB3 ITGB3 29302  
ITGB3 3690 P05106

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All available anti-Integrin beta 3 Antibodies

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Top referenced anti-Integrin beta 3 Antibodies

  1. Human Monoclonal Integrin beta 3 Primary Antibody for IF, WB - ABIN968389 : Chen, Djaffar, Pidard, Steiner, Cieutat, Caen, Rosa et al.: Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann ... in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 5 references for 968389

  2. Human Monoclonal Integrin beta 3 Primary Antibody for IHC (fro), IHC (p) - ABIN114660 : Kanz, Mielke, Fauser: Analysis of human hemopoietic progenitor cells for the expression of glycoprotein IIIa. in Experimental hematology 1988 (PubMed)
    Show all 4 references for 114660

  3. Human Monoclonal Integrin beta 3 Primary Antibody for EIA, IF - ABIN1106489 : Newton, Girgenti, Collier, Duman: Electroconvulsive seizure increases adult hippocampal angiogenesis in rats. in The European journal of neuroscience 2006 (PubMed)
    Show all 3 references for 1106489

  4. Cow (Bovine) Monoclonal Integrin beta 3 Primary Antibody for FACS - ABIN317409 : Pérez de la Lastra, Moreno, Pérez, Llanes: Characterization of the porcine homologue to human platelet glycoprotein IIb-IIIa (CD41/CD61) by a monoclonal antibody. in Tissue antigens 1997 (PubMed)
    Show all 3 references for 317409

  5. Human Polyclonal Integrin beta 3 Primary Antibody for ELISA, IF (cc) - ABIN739029 : Wang, Jiang, Peng, Guo, Shang, Chen, Wu, Chen: Induced apoptosis of osteoblasts proliferating on polyhydroxyalkanoates. in Biomaterials 2013 (PubMed)
    Show all 3 references for 739029

  6. Mouse (Murine) Monoclonal Integrin beta 3 Primary Antibody for FACS, IP - ABIN1449278 : Jonker, Schinkel: Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3). in The Journal of pharmacology and experimental therapeutics 2004 (PubMed)
    Show all 2 references for 1449278

  7. Mouse (Murine) Monoclonal Integrin beta 3 Primary Antibody for FACS - ABIN120248 : Yasuda, Hasunuma, Adachi, Sekine, Sakanishi, Hashimoto, Ra, Yagita, Okumura: Expression and function of fibronectin binding integrins on rat mast cells. in International immunology 1995 (PubMed)

  8. Human Polyclonal Integrin beta 3 Primary Antibody for EIA, WB - ABIN453710 : Wang, Furihata, McFarland, Friedman, Aster, Newman: An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen system. in The Journal of clinical investigation 1992 (PubMed)

  9. Human Monoclonal Integrin beta 3 Primary Antibody for FACS - ABIN4897102 : Park-Min, Lee, Moskowitz, Lim, Lee, Lorenzo, Huang, Melnick, Purdue, Goldring, Ivashkiv: Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012 (PubMed)

More Antibodies against Integrin beta 3 Interaction Partners

Mouse (Murine) Integrin beta 3 (ITGB3) interaction partners

  1. The authors showed the synergistic negative regulation of the pro-inflammatory cytokine interferon-gamma (show IFNG Antibodies) (IFNgamma) and beta3 integrin signaling in murine hematopoietic stem cells function by a novel definitive phenotyping of hematopoietic stem cells.

  2. This study provided evidence in platelets at both static and flow conditions that the calpain cleavage-related sequences of integrin beta3, i.e. T755NITYRGT762, R760GT762, and N756ITY759 participate in bidirectional, outside-in, and inside-out signaling, respectively and the association of c-Src (show SRC Antibodies) or kindlin with beta3 integrin may regulate these processes.

  3. By modulating its affinity with kindlin, beta3 integrin may be able to locate near the cell edge where it can control beta1 integrin activation and clustering.

  4. MiR (show MLXIP Antibodies)-30a-5p suppresses tumor metastasis of human colorectal cancer by targeting ITGB3.

  5. suppression of beta3-integrin in mice leads to the activation of a neuropilin-1 (NRP1 (show NRP1 Antibodies))-dependent cell migration pathway in endothelial cells via a mechanism that depends on NRP1 (show NRP1 Antibodies)'s mobilisation away from mature focal adhesions following VEGF (show VEGFA Antibodies)-stimulation

  6. Deletion of Itgb3 causes increased B-cell responses to TLR stimulation in vitro.

  7. integrin beta3-mediated signaling in smooth muscle cells links elastin (show ELN Antibodies) deficiency and pathological stenosis, and inhibiting this pathway is an attractive therapeutic strategy for supravalvular aortic stenosis.

  8. The clathrin-mediated endocytic machinery combines with Dab2 (show DAB2 Antibodies) to facilitate the endocytosis of RGD-integrin-beta3 clusters.

  9. Integrin beta 3 causes arteriovenous graft occlusion.

  10. Taken together, our results reveal that TD-26 is a novel antithrombotic compound exhibiting both integrin alphaIIbbeta3 inhibition and PI3K signaling blockage, with a low bleeding risk.

Human Integrin beta 3 (ITGB3) interaction partners

  1. overexpression of syndecan-1 confers to B-LCs an increased capacity to migrate in response to Tat, owing to a switch from a CXCR4/G-protein/Rac to a syndecan-1/alphavbeta3/pp60src/pp125FAK signal transduction pathway that depends on the formation of a complex in which syndecan-1 interacts with Tat via its HS-chains, with alphavbeta3 via its core protein ectodomain and with pp60src via its intracellular tail

  2. From these data, we suggest that filamentous vimentin (show VIM Antibodies) underneath the plasma membrane is involved in increasing integrin adhesiveness, and thus regulation of the vimentin (show VIM Antibodies)-integrin interaction might control cell adhesion

  3. Data suggest that talin increases embedding of integrin-beta-3 (ITGB3) transmembrane domain into lipid bilayer, resulting in activation of integrin-alpha-IIb (show ITGA2B Antibodies) beta-3 (ITGA2B (show ITGA2B Antibodies)/ITGB3); phyto-antioxidant EGCG (epigallocatechin gallate) decreases this embedding, thus opposing talin-induced integrin activation. However, EGCG activates ITGA2B (show ITGA2B Antibodies)/ITGB3 in the absence of talin both in a purified system and in CHO (show COL11A1 Antibodies) cells.

  4. In vitro binding assays with purified components reveal that Tie-integrin recognition is direct, and further demonstrate that the receptor binding domain of the Tie2 ligand (show ANGPT2 Antibodies) Ang-1 (show ANGPT1 Antibodies), but not the receptor binding domain of Ang-2 (show ANGPT2 Antibodies), can independently associate with a5b1 or aVb3. cooperative Tie/integrin interactions selectively stimulate ERK/MAPK (show MAPK1 Antibodies) signaling in the presence of both Ang-1 (show ANGPT1 Antibodies) and fibronectin (show FN1 Antibodies)

  5. Recombinant platelet membrane glycoprotein IIIa (GPa (show GYPA Antibodies)) was successfully obtained and used to establish a Luminex technology-based method for the detection of HPA (show HPSE Antibodies)-1a-specific antibodies.

  6. In contrast to HLA-DRB4 (show HLADRB4 Antibodies)*01:01P, the inheritance of HLA-DRB3 (show HLA-DRB3 Antibodies)*01:01 is strongly associated with the propensity for mounting a humoral immune response against fetal HPA (show HPSE Antibodies)-1a antigen.

  7. Case Report: Reduced binding of mutant FLNa (show FLNA Antibodies) to beta3 and the facilitated recruitment of talin by beta3 on platelet stimulation, explaining the increased alphaIIbbeta3 activation and the ensuing gain-of-platelet functions.

  8. Data indicate no association of maternal or fetal ITGA2 (show ITGA2 Antibodies) C807T SNP, ITGB3 T1565C SNP, PECAM1 (show PECAM1 Antibodies) CTG - GTG (show GGT1 Antibodies) and SELP (show SEPP1 Antibodies) A/C polymorphisms with fetal growth restriction (FGR (show FGR Antibodies)).

  9. these results show that differences in stiffness/fluidity due to alphavbeta3 integrin expression or integrin activation by Mn(2+) might not simply be explained by the coupling of integrins to actin via focal adhesions.

  10. These results identify beta3 integrin signaling via repression of BAD as an important survival pathway used by breast cancer cells to evade chemotherapy induced stress.

Pig (Porcine) Integrin beta 3 (ITGB3) interaction partners

  1. The observed effects of shear stress on integrin alpha(v (show ITGAV Antibodies))beta(3) and p38 MAPK (show MAPK14 Antibodies) activation, as well as on FGF-2 (show FGF2 Antibodies) release could be mimicked by application of pancreatic elastase to static endothelial cells.

  2. structure and distribution of the CD61 provides insight into the physiological function of the porcine beta(3) integrins and should be of importance in understanding the role of this integrin family in biological processes

  3. Inhibition of integrin alphavbeta3 (show ITGAV Antibodies) prevents urokinase plasminogen (show PLG Antibodies) activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.

Cow (Bovine) Integrin beta 3 (ITGB3) interaction partners

  1. alphavbeta3 integrin engagement in vascular endothelium regulates Ca2 (show CA2 Antibodies)+-dependent K+ current

  2. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

Integrin beta 3 (ITGB3) Antigen Profile

Antigen Summary

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Alternative names and synonyms associated with Integrin beta 3 (ITGB3)

  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3) antibody
  • integrin beta 3 (Itgb3) antibody
  • integrin, beta 3 (Itgb3) antibody
  • BDPLT2 antibody
  • BDPLT16 antibody
  • CD61 antibody
  • GP3A antibody
  • GPIIIA antibody
  • GT antibody
  • INGRB3 antibody
  • INTB3 antibody
  • integrin antibody

Protein level used designations for anti-Integrin beta 3 (ITGB3) Antibodies

integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) , integrin beta3 , GPIIIa , integrin beta-3 , platelet gpIIIa , platelet membrane glycoprotein IIIa , integrin beta 3 (Cd61) , beta3 integrin , glycoprotein GPIIIa , integrin beta 3 , integrin beta-3 subunit

100423047 Ovis aries
16416 Mus musculus
29302 Rattus norvegicus
3690 Homo sapiens
397063 Sus scrofa
282642 Bos taurus
374209 Gallus gallus
403788 Canis lupus familiaris
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