Browse our POR Proteins (POR)

Full name:
P450 (Cytochrome) Oxidoreductase Proteins (POR)
On are 18 P450 (Cytochrome) Oxidoreductase (POR) Proteins from 7 different suppliers available. Additionally we are shipping POR Antibodies (121) and POR Kits (20) and many more products for this protein. A total of 165 POR products are currently listed.
2310002N04Rik, 4933424M13Rik, CCR, CG11567, cpr, CYPOR, DmCPR, Dmel\\CG11567, DMR, NCPR, npr, P450, P450R, POR, Por1, PORCINO, T5J17.90, T5J17_90, TFC C, TUBULIN-FOLDING COFACTOR C, xpor, zgc:110032
list all proteins Gene Name GeneID UniProt
POR 76932 Q8K221
POR 293344 Q6AY65
POR 5447 P16435

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POR Proteins (POR) by Origin

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More Proteins for POR Interaction Partners

Mouse (Murine) P450 (Cytochrome) Oxidoreductase (POR) interaction partners

  1. we observed that miR (show MLXIP Proteins)-378 modulates the oscillation amplitudes of Cdkn1a (show CDKN1A Proteins) in the control of cell cycle and Por in the regulation of oxidation reduction by forming partnership with different circadian transcription factors

  2. Highest level of Rac1 activation was achieved on the smallest nanofibers, a trend that was lost in POR1 knockdown. This supports the hypothesis that on small nanofibers, POR1 binds to highly curved cell membranes, allowing Rac1 to dissociate and activate.

  3. Results are the first to show that some forms of opioid-mediated stress-induced analgesia require brain neuronal P450 activity.

  4. Immunological and metabolic changes resulting from a genetic deficiency in CPR (show GRID2 Proteins) expression in the intestine in mice.

  5. An apparent link exists between the cytochrome p450 reductase and FGF signaling pathways.

  6. These data collectively indicate a novel role of the Cpr (show GRID2 Proteins) gene in fear conditioning and memory.

  7. this study provides novel insights into the regulation of gap junction function by CYPOR and suggests that Cx43 (show GJA1 Proteins) may play an important role(s) in CYPOR-mediated bone defects seen in patients.

  8. inactivation of the hepatic cytochrome P450 system by conditional deletion of this enzyme

  9. Changes in hepatic mRNA expression using microarray analysis and real-time PCR in POR null mice are reported.

  10. POR function is indispensable for the proper regulation of retinoic acid levels and tissue distribution not only during early embryonic development but also in later morphogenesis and molecular patterning of the brain, abdominal/caudal region and limbs.

Xenopus laevis P450 (Cytochrome) Oxidoreductase (POR) interaction partners

  1. NADPH-P450 reductase (NPR) was purified from hepatic microsomes of Xenopus laevis.

Human P450 (Cytochrome) Oxidoreductase (POR) interaction partners

  1. To promote intracellular iron flux, an iron chaperone appears to be essential for receiving iron from heme catabolism. Data suggest that PCBP2 (show PCBP2 Proteins) competes with CPR for binding HO1 (show HMOX1 Proteins); PCBP2 (show PCBP2 Proteins) K homology 3 domain is important for HO1 (show HMOX1 Proteins)/PCBP2 (show PCBP2 Proteins) interaction; heme prompts HO1 (show HMOX1 Proteins)/CPR multimer and decreases HO1 (show HMOX1 Proteins)/PCBP2 (show PCBP2 Proteins) multimer. [PCBP2 (show PCBP2 Proteins) = poly(rC) binding protein 2 (show PCBP2 Proteins); CPR = cytochrome P450 reductase; HO1 (show HMOX1 Proteins) = heme oxidase 1]

  2. analysis of mutations and polymorphisms in POR linked to metabolism of steroids and xenobiotics and pathology of P450 (show CYP2B6 Proteins) oxidoreductase (show TXNRD1 Proteins) deficiency (PORD)

  3. No significant differences in the distribution of haplotypes between cases and controls were detected. In conclusion, this study reveals that four SNPs in the POR gene (rs3823884, rs3898649, rs239953 and rs17685) may affect the susceptibility of smoking cessation in a Chinese Han population.

  4. analysis of the role of the active site loop in coenzyme binding and flavin reduction in cytochrome P450 reductase

  5. Current studies demonstrate that, unlike previously described mutations, A287P causes POR deficiency disorder due to conformational instability leading to proteolytic susceptibility in vivo, rather than through an inherent flavin-binding defect.

  6. population pharmacokinetic analysis identified that the combined genotype of CYP3A5 (show CYP3A5 Proteins)-POR was the only covariant for the apparent clearance of tacrolimus

  7. Case Report: delayed diagnosis of 46, XY disorder of sex development due to P450 (show CYP2B6 Proteins) oxidoreductase (show TXNRD1 Proteins) (POR) deficiency.

  8. Interindividual variability in CYP2C19 (show CYP2C19 Proteins) activity is due to differences in both CYP2C19 (show CYP2C19 Proteins) protein content associated with gene diplotypes and the cytochrome P450 oxidoreductase (show TXNRD1 Proteins) content.

  9. POR rs2868177 and CYP2B6 (show CYP2B6 Proteins)*6 variants contribute to the interindividual variability in human CYP2B6 (show CYP2B6 Proteins) activity, which may affect the disposition and interaction of other CYP2B6 (show CYP2B6 Proteins) substrate drugs

  10. For the first time, the SNP POR*37 831-35C>T was confirmed as a minor but statistically significant factor associated with inter-individual variation in warfarin maintenance dose in Han Chinese

Rabbit P450 (Cytochrome) Oxidoreductase (POR) interaction partners

  1. Data indicate not only that binding of b5 and P450 reductase on the proximal surface of P450 2B4 (show CD244 Proteins) results in electron transfer but also that each redox partner transmits unique structural information to the active site proton delivery network.

POR Protein Profile

Protein Summary

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Alternative names and synonyms associated with POR

  • Cytochrome P450 reductase (Cpr)
  • P450 (cytochrome) oxidoreductase (POR)
  • P450 (cytochrome) oxidoreductase (por)
  • ADP-ribosylation factor interacting protein 2 (Arfip2)
  • P450 (cytochrome) oxidoreductase (Por)
  • tubulin-folding cofactor C (POR)
  • 2310002N04Rik protein
  • 4933424M13Rik protein
  • CCR protein
  • CG11567 protein
  • cpr protein
  • CYPOR protein
  • DmCPR protein
  • Dmel\\CG11567 protein
  • DMR protein
  • NCPR protein
  • npr protein
  • P450 protein
  • P450R protein
  • POR protein
  • Por1 protein
  • PORCINO protein
  • T5J17.90 protein
  • T5J17_90 protein
  • TFC C protein
  • xpor protein
  • zgc:110032 protein

Protein level used designations for POR

CG11567-PA , CG11567-PB , CG11567-PC , CG11567-PD , Cpr-PA , Cpr-PB , Cpr-PC , Cpr-PD , NADPH-cytochrome P450 oxidoreductase , P450 reductase , cytochrome P450 reductase , cytochrome c reductase (NADPH) , P450 (cytochrome) oxidoreductase , NADPH--cytochrome P450 reductase-like , ADP-ribosylation factor-interacting protein 2 , Arfaptin 2 , arfaptin-2 , partner of RAC1 , ADP-ribosylation factor interacting protein 2 (arfaptin 2) , partner of Rac1 , CPR , NADPH--cytochrome P450 reductase , P450R , NADPH-P450 reductase , NADPH-dependent cytochrome P450 reductase , NADPH-cytochrome P450 reductase , NADPH-cytochrome P-450 oxidoreductase , NADH cytochrome P450 oxydoreductase

33883 Drosophila melanogaster
463481 Pan troglodytes
715888 Macaca mulatta
100406157 Callithrix jacchus
100486781 Xenopus (Silurana) tropicalis
100587002 Nomascus leucogenys
100619047 Monodelphis domestica
76932 Mus musculus
293344 Rattus norvegicus
532512 Bos taurus
29441 Rattus norvegicus
568202 Danio rerio
379707 Xenopus laevis
417520 Gallus gallus
5447 Homo sapiens
489816 Canis lupus familiaris
100170114 Sus scrofa
18984 Mus musculus
100135602 Cavia porcellus
830151 Arabidopsis thaliana
100301554 Oryctolagus cuniculus
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