POR Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712813

Product Details

Target: POR (P450 (Cytochrome) Oxidoreductase (POR))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This POR protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Cytochrome P450 Reductase protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: POR (P450 (Cytochrome) Oxidoreductase (POR))

Alternative Name: Cytochrome p450 Reductase (POR Products)

Synonyms: CPR Protein, CYPOR Protein, P450R Protein, POR Protein, CCR Protein, CG11567 Protein, DMR Protein, DmCPR Protein, Dmel\\CG11567 Protein, NCPR Protein, P450 Protein, cpr Protein, zgc:110032 Protein, npr Protein, xpor Protein, 4933424M13Rik Protein, PORCINO Protein, T5J17.90 Protein, T5J17_90 Protein, TFC C Protein, TUBULIN-FOLDING COFACTOR C Protein, cytochrome p450 oxidoreductase Protein, P450 (cytochrome) oxidoreductase Protein, ADP-ribosylation factor interacting protein 2 Protein, Cytochrome P450 reductase Protein, P450 (cytochrome) oxidoreductase a Protein, P450 (cytochrome) oxidoreductase L homeolog Protein, NADPH--cytochrome P450 reductase Protein, C-CAP/cofactor C-like domain-containing protein Protein, POR Protein, Arfip2 Protein, Por Protein, Cpr Protein, pora Protein, por.L Protein, LOC100406157 Protein, por Protein, LOC100619047 Protein

Background: This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Molecular Weight: 76.9 kDa

NCBI Accession: NP_000932

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome