Browse our anti-Lymphocyte-Activation Gene 3 (LAG3) Antibodies

Full name:
anti-Lymphocyte-Activation Gene 3 Antibodies (LAG3)
On www.antibodies-online.com are 223 Lymphocyte-Activation Gene 3 (LAG3) Antibodies from 24 different suppliers available. Additionally we are shipping Lymphocyte-Activation Gene 3 Proteins (45) and Lymphocyte-Activation Gene 3 Kits (18) and many more products for this protein. A total of 292 Lymphocyte-Activation Gene 3 products are currently listed.
Synonyms:
CD223, LAG-3, Ly66

Most Popular Reactivities for anti-Lymphocyte-Activation Gene 3 (LAG3) Antibodies

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Top referenced anti-Lymphocyte-Activation Gene 3 Antibodies

  1. Human Monoclonal LAG3 Primary Antibody for FACS - ABIN4329756 : Demeure, Wolfers, Martin-Garcia, Gaulard, Triebel: T Lymphocytes infiltrating various tumour types express the MHC class II ligand lymphocyte activation gene-3 (LAG-3): role of LAG-3/MHC class II interactions in cell-cell contacts. in European journal of cancer (Oxford, England : 1990) 2001 (PubMed)
    Show all 9 references for 4329756

  2. Human Monoclonal LAG3 Primary Antibody for FACS, ICC - ABIN4329753 : Casati, Camisaschi, Novellino, Mazzocchi, Triebel, Rivoltini, Parmiani, Castelli: Human lymphocyte activation gene-3 molecules expressed by activated T cells deliver costimulation signal for dendritic cell activation. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 9 references for 4329753

  3. Human Polyclonal LAG3 Primary Antibody for FACS - ABIN4896615 : Melve, Ersvaer, Akkök, Ahmed, Kristoffersen, Hervig, Bruserud: Immunomodulation Induced by Stem Cell Mobilization and Harvesting in Healthy Donors: Increased Systemic Osteopontin Levels after Treatment with Granulocyte Colony-Stimulating Factor. in International journal of molecular sciences 2016 (PubMed)
    Show all 5 references for 4896615

  4. Mouse (Murine) Monoclonal LAG3 Primary Antibody for FACS - ABIN120325 : Workman, Rice, Dugger, Kurschner, Vignali: Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). in European journal of immunology 2002 (PubMed)
    Show all 2 references for 120325

  5. Human Polyclonal LAG3 Primary Antibody for FACS, WB - ABIN4899757 : Porichis, Kwon, Zupkosky, Tighe, McMullen, Brockman, Pavlik, Rodriguez-Garcia, Pereyra, Freeman, Kavanagh, Kaufmann: Responsiveness of HIV-specific CD4 T cells to PD-1 blockade. in Blood 2011 (PubMed)
    Show all 2 references for 4899757

  6. Mouse (Murine) Monoclonal LAG3 Primary Antibody for FACS - ABIN120324 : Workman, Vignali: Negative regulation of T cell homeostasis by lymphocyte activation gene-3 (CD223). in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
    Show all 2 references for 120324

  7. Human Polyclonal LAG3 Primary Antibody for FACS, IF (cc) - ABIN748508 : Parodi, Battaglia, Kalli, Ferrera, Conteduca, Tardito, Stringara, Ivaldi, Negrini, Borgonovo, Simonato, Traverso, Carmignani, Fenoglio, Filaci: CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes. in Cancer immunology, immunotherapy : CII 2013 (PubMed)

  8. Human Polyclonal LAG3 Primary Antibody for FACS, WB - ABIN4899755 : Illingworth, Butler, Roetynck, Mwacharo, Pierce, Bejon, Crompton, Marsh, Ndungu: Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion. in Journal of immunology (Baltimore, Md. : 1950) 2013 (PubMed)

  9. Human Monoclonal LAG3 Primary Antibody for FACS - ABIN4896610 : Kong, Zhang, Claxton, Ehmann, Rybka, Zhu, Zeng, Schell, Zheng: PD-1(hi)TIM-3(+) T cells associate with and predict leukemia relapse in AML patients post allogeneic stem cell transplantation. in Blood cancer journal 2015 (PubMed)

More Antibodies against Lymphocyte-Activation Gene 3 Interaction Partners

Cow (Bovine) Lymphocyte-Activation Gene 3 (LAG3) interaction partners

Rhesus Monkey Lymphocyte-Activation Gene 3 (LAG3) interaction partners

  1. We show that the expression of LAG3 is highly induced in the lungs and particularly in the granulomatous lesions of macaques experimentally infected with mycobacterium tuberculosis.

Mouse (Murine) Lymphocyte-Activation Gene 3 (LAG3) interaction partners

  1. Study suggests that expression of the inhibitory receptors PD-1 (show PDCD1 Antibodies) and LAG-3 on CD4 (show CD4 Antibodies)(+) T cells and their reduced IL-2 (show IL2 Antibodies) production are common characteristic features of Plasmodium infection.

  2. An IL-27 (show IL27 Antibodies)/Lag3 axis enhances Foxp3 (show FOXP3 Antibodies)+ regulatory T cell-suppressive function and therapeutic efficacy.

  3. LAG3 and PD1 (show PDCD1 Antibodies) co-inhibitory molecules have roles in collaborating to limit CD8 (show CD8A Antibodies)+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model

  4. Poxvirus-Based Active Immunotherapy with PD-1 (show PDCD1 Antibodies) and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice.

  5. Lymphatic endothelial cells (LECs) serve as an antigen reservoir for CD4 (show CD4 Antibodies) T-cell tolerance, and MHC-II molecules on LECs are used to induce CD8 (show CD8A Antibodies) T-cell tolerance via LAG-3.

  6. LAG-3 expression on Tconv cells makes them more susceptible to Treg based suppression, and also regulates the development of a TH1 (show HAND1 Antibodies) T-cell response.

  7. LAG-3 exerts an important regulatory effect on autoimmunity.

  8. Lag-3 is an important regulatory molecule involved in alloreactive T cell proliferation and activation after bone marrow transplantation.

  9. these results define a strong synergy between the PD-1 (show PDCD1 Antibodies) and LAG-3 inhibitory pathways in tolerance to both self and tumor antigens.

  10. We conclude that LAG-3 is necessary for regulating CD4 (show CD4 Antibodies)(+) and CD8 (show CD8A Antibodies)(+) T cell function during autoimmune diabetes

Human Lymphocyte-Activation Gene 3 (LAG3) interaction partners

  1. this review provides the translational rationale for targeting LAG3, as well as historical and current state of clinical trials utilizing LAG3 cancer immunomodulators

  2. this study shows that LAG3 expressed on myeloid leukaemia cells possess the capacity to facilitate functional exhaustion in T helper cells

  3. epigenetic modification on LAG-3 increased LAG-3(+) T cells and its immune regulatory roles in chronic osteomyelitis progression

  4. Immune checkpoint proteins are co-inhibitory factors that can diminish the antigen-specific immune responses by attenuating the regulatory role of cytotoxic T-lymphocyte-associated protein 4 (show CTLA4 Antibodies), programmed cell death-1 (show PDCD1 Antibodies), lymphocyte-activation gene 3, and T-cell immunoglobulin mucin-3 (show HAVCR2 Antibodies).

  5. LAG3 binds alpha-synuclein (show SNCA Antibodies) preformed fibrils (PFF) with high affinity (dissociation constant = 77 nanomolar), whereas the alpha-syn monomer exhibited minimal binding. alpha-Syn-biotin PFF binding to LAG3 initiated alpha-syn PFF endocytosis, transmission, and toxicity.

  6. An IL-27 (show IL27 Antibodies)/Lag3 axis enhances Foxp3 (show FOXP3 Antibodies)+ regulatory T cell-suppressive function and therapeutic efficacy.

  7. LAG-3 is highly expressed in peripheral blood CD8 (show CD8A Antibodies)+ T cells in chronic HBV-infected patients.

  8. Data indicate that in recurrent spontaneous abortion patients, the expression levels of CD49b (show ITGA2 Antibodies) and LAG-3 (CD223) on CD14 (show NDUFA2 Antibodies)(+) mononuclear cells and the plasma level of transforming growth factor beta (TGF-beta) decreased obviously compared with normal females.

  9. iNKT cytokine production is profoundly altered by both HIV infection and treatment, and LAG-3, but not PD-1 (show PDCD1 Antibodies), expression is associated with a reduction in iNKT IFNgamma production.

  10. NFKB1 (show NFKB1 Antibodies), CD27 (show CD27 Antibodies), LAG3 and IKZF3 (show IKZF3 Antibodies) are new susceptibility genes for psoriasis.

Lymphocyte-Activation Gene 3 (LAG3) Antigen Profile

Antigen Summary

Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.

Alternative names and synonyms associated with Lymphocyte-Activation Gene 3 (LAG3)

  • lymphocyte-activation gene 3 (LAG3) antibody
  • lymphocyte-activation gene 3 (Lag3) antibody
  • CD223 antibody
  • LAG-3 antibody
  • Ly66 antibody

Protein level used designations for LAG3

lymphocyte-activation gene 3 , lymphocyte-activation protein 3 , lymphocyte-activation protein 3-like , lymphocyte activation gene 3 protein-like , lymphocyte activation gene 3 protein , LAG-3 , lymphocyte activation gene 3

GENE ID SPECIES
418287 Gallus gallus
451794 Pan troglodytes
515155 Bos taurus
713737 Macaca mulatta
100059998 Equus caballus
100415501 Callithrix jacchus
100452007 Pongo abelii
16768 Mus musculus
3902 Homo sapiens
297596 Rattus norvegicus
100125962 Sus scrofa
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