LAG3 antibody (AA 1-360)
Quick Overview for LAG3 antibody (AA 1-360) (ABIN517422)
Target
See all LAG3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-360
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Purpose
- Rabbit polyclonal antibody raised against a full-length human LAG3 protein.
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Sequence
- MWEAQFLGLL FLQPLWVAPV KPLQPGAEVP VVWAQEGAPA QLPCSPTIPL QDLSLLRRAG VTWQHQPDSG PPAAAPGHPL APGPHPAAPS SWGPRPRRYT VLSVGPGGLR SGRLPLQPRV QLDERGRQRG DFSLWLRPAR RADAGEYRAA VHLRDRALSC RLRLRLGQAS MTASPPGSLR ASDWVILNCS FSRPDRPASV HWFRNRGQGR VPVRESPHHH LAESFLFLPQ VSPMDSGPWG CILTYRDGFN VSIMYNLTVL GLEPPTPLTV YAGAGSRVGL PCRLPAGVGT RSFLTAKWTP PGGGPDLLVT GDNGDFTLRL EDVSQAQAGT YTCHIHLQEQ QLNATVTLAI ITGQPQVGKE
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Cross-Reactivity
- Human
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Characteristics
- Antibody reactive against mammalian transfected lysate.
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Immunogen
- LAG3 (AAH52589.1, 1 a.a. ~ 360 a.a) full-length human protein.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- In 1x PBS, pH 7.4
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "CRYAB modulates the activation of CD4+ T cells from relapsing-remitting multiple sclerosis patients." in: Multiple sclerosis (Houndmills, Basingstoke, England), Vol. 19, Issue 14, pp. 1867-77, (2013) (PubMed).
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- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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Alternative Name
- LAG3
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Background
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Full Gene Name: lymphocyte-activation gene 3
Synonyms: CD223 -
Gene ID
- 3902
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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