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Browse our anti-P2RX7 (P2RX7) Antibodies

Full name:
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 Antibodies (P2RX7)
On www.antibodies-online.com are 122 Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antibodies from 19 different suppliers available. Additionally we are shipping P2RX7 Kits (14) and P2RX7 Proteins (8) and many more products for this protein. A total of 153 P2RX7 products are currently listed.
Synonyms:
AI467586, P2RX7, P2X(7), p2x7, P2X7R, p2xr7
list all antibodies Gene Name GeneID UniProt
P2RX7 5027 Q99572
P2RX7 18439 Q9Z1M0
P2RX7 29665 Q64663

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Most Popular Reactivities for anti-P2RX7 (P2RX7) Antibodies

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anti-Human P2RX7 Antibodies:

anti-Mouse (Murine) P2RX7 Antibodies:

anti-Rat (Rattus) P2RX7 Antibodies:

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Top referenced anti-P2RX7 Antibodies

  1. Human Polyclonal P2RX7 Primary Antibody for IHC (p), WB - ABIN651861 : Kim, Jiang, Wilson, North, Surprenant: Proteomic and functional evidence for a P2X7 receptor signalling complex. in The EMBO journal 2001 (PubMed)
    Show all 2 references for ABIN651861

  2. Human Polyclonal P2RX7 Primary Antibody for IHC (p), IHC - ABIN451826 : Tomasinsig, Pizzirani, Skerlavaj, Pellegatti, Gulinelli, Tossi, Di Virgilio, Zanetti: The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner. in The Journal of biological chemistry 2008 (PubMed)

  3. Dog (Canine) Polyclonal P2RX7 Primary Antibody for WB - ABIN2776151 : Al-Shukaili, Al-Kaabi, Hassan: A comparative study of interleukin-1beta production and p2x7 expression after ATP stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls. in Inflammation 2008 (PubMed)

  4. Cow (Bovine) Polyclonal P2RX7 Primary Antibody for IHC, WB - ABIN2776335 : Buell, Talabot, Gos, Lorenz, Lai, Morris, Antonarakis: Gene structure and chromosomal localization of the human P2X7 receptor. in Receptors & channels 1999 (PubMed)

More Antibodies against P2RX7 Interaction Partners

Zebrafish Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. Blockade of the P2X7 receptor reduces cyst formation via ERK (show MAPK1 Antibodies)-dependent pathways in a zebrafish model of polycystic kidney disease.

Human Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. the biochemical and molecular knowledge of P2X7R in IFCD is useful to shed further light about the participation of purinergic system in the pathogenesis of CD, and consequently, may help to avoid the progression of disease.

  2. The P2X7R rs3751142 genetic variants was not implicated in the development of gout in the male Korean population. However, we found that in a pair-wise comparison of the CA/TT P2X7R and CARD8 (show CARD8 Antibodies) genotype combination was shown to have an increased trend for the risk of gout.

  3. Five gene polymorphisms, -762C>T (rs2393799), 946G>A (rs28360457), 1513A>C (rs3751143), 1068G>A (rs1718119), and 1096C>G (rs2230911), were selected. Our results suggest that 3 of the 5 polymorphisms of P2RX7 described above (1513A>C, 946G>A, and 1068G>A) are significantly associated with Hepatocellular Carcinoma susceptibility in a Chinese Han population.

  4. a local Ca(2 (show CA2 Antibodies)+) signal near a fragment that encodes the intracellular P2X2R C-terminus tail is sufficient to trigger blebbing

  5. Overexpression of P2RX7 is associated with uveal melanoma.

  6. there is a relationship between the elevated expression of P2X3 (show P2RX3 Antibodies) receptor and P2X7 receptor in peripheral blood leukocytes and high serum epinephrine and norepinephrine levels in hyperthyroidism patients.

  7. a pivotal role of P2X7 receptor-pannexin-1 (show PANX1 Antibodies) in oxysterols toxicity in retinal cells

  8. significant upregulation of P2X7R and increased IL-1beta (show IL1B Antibodies) release seems to be a particular phenomenon in patients with neuropathic pain

  9. We identified potential nuclear and membrane biomarkers (increased expression of ZO-1 (show TJP1 Antibodies), caveolin-1 (show CAV1 Antibodies) and P2X7 receptor) of risks for placenta and pregnancy

  10. The association between independent P2X7R polymorphisms with stress fracture prevalence supports the role of a genetic predisposition in the development of stress fracture

Cow (Bovine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. For the inflammasome-dependent IL-1beta (show IL1B Antibodies) release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta (show IL1B Antibodies) release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor.

Mouse (Murine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. lncRNA A30P01019163 may affect ovarian cell cycle and proliferation by regulating P2rx7 expression in the ovary.

  2. both synergic and additive relationships are found within P2X7, cationic, and anionic large pores

  3. P2X7R stimulation in macrophages is able to release potent anti-inflammatory proteins, such as Annexin A1 (show ANXA1 Antibodies), independently of their polarization state suggesting for first time a potential role for P2X7R during resolution of the inflammation and not linked to the release of pro-inflammatory cytokines.

  4. These results indicate that activation of Panx1 (show PANX1 Antibodies) and P2X7 R are required for apoptotic osteocytes in fatigued bone to trigger RANKL (show TNFSF11 Antibodies) production in neighboring bystander osteocytes and implicate ATP as an essential signal mediating this process.

  5. A role for post-transcriptional regulation of the P2X7R in epilepsy

  6. We also demonstrate extracellular ATP participates in regulation of inflammatory responses of colitis, through P2 x 7 receptor and inflammasome and NFkappaB signaling.

  7. we reveal that neuronal vulnerability to ATP depends on the expression level of P2X7R

  8. Activation of P2X7 by ATP induced the release of TNFalpha (show TNF Antibodies) from microglia which protected neurons from NMDA-induced excitotoxicity, might also account for neuroprotective properties of valproic acid

  9. Data provide mechanistic insights into the role of KHG26792 in the inhibition of TNF-alpha (show TNF Antibodies) produced via purinergic receptor P2X7 receptor-mediated activation of NFAT (show NFATC1 Antibodies) and MAPK (show MAPK1 Antibodies) pathways in adenosine triphosphate-treated BV-2 cells.

  10. Results suggest that P2X7R is an important activator of the immune response that leads to type 1 diabetes.

P2RX7 Antigen Profile

Antigen Summary

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.

Alternative names and synonyms associated with P2RX7

  • purinergic receptor P2X, ligand-gated ion channel, 7 (P2RX7) antibody
  • purinergic receptor P2X, ligand-gated ion channel, 7 (p2rx7) antibody
  • purinergic receptor P2X, ligand-gated ion channel, 7 (P2rx7) antibody
  • AI467586 antibody
  • P2RX7 antibody
  • P2X(7) antibody
  • p2x7 antibody
  • P2X7R antibody
  • p2xr7 antibody

Protein level used designations for P2RX7

P2X purinoceptor 7 , purinergic receptor P2X, ligand-gated ion channel, 7 , p2X purinoceptor 7-like , ATP receptor , P2X7 receptor , P2Z receptor , purinergic receptor P2X7 variant A , P2X7 purinoceptor , purinergic receptor P2X7

GENE ID SPECIES
100058464 Equus caballus
387298 Danio rerio
452318 Pan troglodytes
699455 Macaca mulatta
771952 Gallus gallus
100458463 Pongo abelii
100588362 Nomascus leucogenys
5027 Homo sapiens
448778 Canis lupus familiaris
286814 Bos taurus
18439 Mus musculus
29665 Rattus norvegicus
497623 Sus scrofa
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