Browse our anti-P2RX7 (P2RX7) Antibodies

Full name:
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 Antibodies (P2RX7)
On www.antibodies-online.com are 120 Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antibodies from 20 different suppliers available. Additionally we are shipping P2RX7 Kits (16) and P2RX7 Proteins (8) and many more products for this protein. A total of 153 P2RX7 products are currently listed.
Synonyms:
AI467586, P2RX7, P2X(7), p2x7, P2X7R, p2xr7
list all antibodies Gene Name GeneID UniProt
P2RX7 5027 Q99572
P2RX7 18439 Q9Z1M0
P2RX7 29665 Q64663

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Most Popular Reactivities for anti-P2RX7 (P2RX7) Antibodies

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anti-Human P2RX7 Antibodies:

anti-Mouse (Murine) P2RX7 Antibodies:

anti-Rat (Rattus) P2RX7 Antibodies:

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Top referenced anti-P2RX7 Antibodies

  1. Rat (Rattus) Polyclonal P2RX7 Primary Antibody for WB - ABIN1742370 : Young, Brutkowski, Lien, Arkle, Lochmüller, Zabłocki, Górecki: P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment. in Journal of cellular and molecular medicine 2012 (PubMed)
    Show all 3 references for 1742370

  2. Human Polyclonal P2RX7 Primary Antibody for IHC (p), WB - ABIN651861 : Kim, Jiang, Wilson, North, Surprenant: Proteomic and functional evidence for a P2X7 receptor signalling complex. in The EMBO journal 2001 (PubMed)
    Show all 2 references for 651861

  3. Cow (Bovine) Polyclonal P2RX7 Primary Antibody for IHC, WB - ABIN2776335 : Buell, Talabot, Gos, Lorenz, Lai, Morris, Antonarakis: Gene structure and chromosomal localization of the human P2X7 receptor. in Receptors & channels 1999 (PubMed)
    Show all 2 references for 2776335

  4. Cow (Bovine) Polyclonal P2RX7 Primary Antibody for WB - ABIN2776151 : Al-Shukaili, Al-Kaabi, Hassan: A comparative study of interleukin-1beta production and p2x7 expression after ATP stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls. in Inflammation 2008 (PubMed)

  5. Human Polyclonal P2RX7 Primary Antibody for IF (p), IHC (p) - ABIN1386314 : Peng, Liu, Wei, Lv, Wang, Xiong, Wang, Altaf, Wang, He, Wang, Qu: P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation. in International journal of molecular medicine 2015 (PubMed)

  6. Human Polyclonal P2RX7 Primary Antibody for IHC (p), IHC - ABIN451826 : Tomasinsig, Pizzirani, Skerlavaj, Pellegatti, Gulinelli, Tossi, Di Virgilio, Zanetti: The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against P2RX7 Interaction Partners

Zebrafish Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. Blockade of the P2X7 receptor reduces cyst formation via ERK (show MAPK1 Antibodies)-dependent pathways in a zebrafish model of polycystic kidney disease.

Human Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. In vitro and in vivo results provide support for the involvement of an oxidative stress through P2X7 receptor activation and mitochondrial dysfunction in the pathophysiology of oxaliplatin-induced neuronal injury and likely to painful neuropathy.

  2. Eight Single nucleotide polymorphisms loci, including rs1653624, rs10160951, rs1718119, rs7958316, rs16950860, rs208294, rs17525809 and rs2230912, were screened and detected, and rs1653624, rs7958316 and rs17525809 were associated with gout arthritis. P2X7R function associated single nucleotide polymorphisms may be related to gouty arthritis.

  3. The loss-of-function SNP rs2230911 in P2X7, that negatively affect NLRP3 (show NLRP3 Antibodies)-inflammasome activation, confers susceptibility toward active pulmonary tuberculosis in Brazilian Amazon cohort.

  4. this review discusses P2X7R structure and its contribution to inflammation and host defense

  5. P2X7R expression was correlated with enhanced tumor grade and metastasis in colorectal carcinoma patients.

  6. Our present study shows that loss of function of the P2X7 receptor in mice induces retinal changes representing characteristics of early age-related macular degeneration.

  7. Single nucleotide polymorphism in P2X7R gene is associated with pulmonary non-tuberculous mycobacterial disease.

  8. Our results reveal that P2RX7 rs2230911 may be associated with primary gout risk in a Chinese Han male population and allele G may be a susceptibility factor for primary gout.

  9. Together, this body of research suggests that P2X7R may constitute an important therapeutic target for a variety of neurological disorders.

  10. In addition, purinergic receptor P2X, ligand-gated ion channel (show GLRa3 Antibodies) 7 (P2X7) was downregulated in CD36 (show CD36 Antibodies)-knockdown 3T3-L1 cells, suggesting that the suppression of CD36 (show CD36 Antibodies) attenuates adipogenesis via the P2X7 pathway in 3T3-L1 cells.

Cow (Bovine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. For the inflammasome-dependent IL-1beta (show IL1B Antibodies) release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta (show IL1B Antibodies) release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor.

Mouse (Murine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. P2X7R activation induces the production of proinflammatory cytokines, including IL-1beta (show IL1B Antibodies) and IL-18 (show IL18 Antibodies), by inducing the oligomerization of the multiprotein complex NLRP3 (show NLRP3 Antibodies)-type inflammasome.

  2. In vitro and in vivo results provide support for the involvement of an oxidative stress through P2X7 receptor activation and mitochondrial dysfunction in the pathophysiology of oxaliplatin-induced neuronal injury and likely to painful neuropathy.

  3. there are several potential mechanisms for the antidepressant phenotype of P2rx7-/- mice, such as the absence of P2rx7-mediated glutamate (show GRIN1 Antibodies) release, elevated basal BDNF (show BDNF Antibodies) production, enhanced neurogenesis and increased 5-HT (show DDC Antibodies) bioavailability in the hippocampus.

  4. This study provides a new insight into malaria immunology by showing the importance of P2X7 receptor in controlling the fine-tuning between Th1 (show HAND1 Antibodies) and Tfh cell differentiation during P. chabaudi infection

  5. Critical Role for P2X7 Receptor-Induced VCAM-1 (show VCAM1 Antibodies) Shedding and Neutrophil Infiltration during Acute Lung Injury

  6. this review discusses P2X7R structure and its contribution to inflammation and host defense

  7. These data support that P2X7 and P2X4 (show P2RX4 Antibodies) receptor activation has a protective effect during severe Escherichia coli infection.

  8. P2X7 deficiency resolved atherosclerotic plaque inflammation by inhibition of inflammasome activation.

  9. P2RX7 purinoceptor gene knockout alters some of the morphological and mechanical properties of dystrophic bones in a mouse model.

  10. restoration of cholesterol concentrations in cells lacking lipin-2 (show LPIN2 Antibodies) decreases ion currents through the P2X7 receptor, and downstream events that drive IL-1beta (show IL1B Antibodies) production.

P2RX7 Antigen Profile

Antigen Summary

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.

Alternative names and synonyms associated with P2RX7

  • purinergic receptor P2X, ligand-gated ion channel, 7 (P2RX7) antibody
  • purinergic receptor P2X, ligand-gated ion channel, 7 (p2rx7) antibody
  • purinergic receptor P2X, ligand-gated ion channel, 7 (P2rx7) antibody
  • AI467586 antibody
  • P2RX7 antibody
  • P2X(7) antibody
  • p2x7 antibody
  • P2X7R antibody
  • p2xr7 antibody

Protein level used designations for P2RX7

P2X purinoceptor 7 , purinergic receptor P2X, ligand-gated ion channel, 7 , p2X purinoceptor 7-like , ATP receptor , P2X7 receptor , P2Z receptor , purinergic receptor P2X7 variant A , P2X7 purinoceptor , purinergic receptor P2X7

GENE ID SPECIES
100058464 Equus caballus
387298 Danio rerio
452318 Pan troglodytes
699455 Macaca mulatta
771952 Gallus gallus
100458463 Pongo abelii
100588362 Nomascus leucogenys
5027 Homo sapiens
448778 Canis lupus familiaris
286814 Bos taurus
18439 Mus musculus
29665 Rattus norvegicus
497623 Sus scrofa
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