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Browse our anti-P2RX7 (P2RX7) Antibodies

Full name:
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 Antibodies (P2RX7)
On are 117 Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antibodies from 19 different suppliers available. Additionally we are shipping P2RX7 Kits (15) and P2RX7 Proteins (8) and many more products for this protein. A total of 149 P2RX7 products are currently listed.
AI467586, P2RX7, P2X(7), p2x7, P2X7R, p2xr7
list all antibodies Gene Name GeneID UniProt
P2RX7 5027 Q99572
P2RX7 18439 Q9Z1M0
P2RX7 29665 Q64663

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anti-Human P2RX7 Antibodies:

anti-Mouse (Murine) P2RX7 Antibodies:

anti-Rat (Rattus) P2RX7 Antibodies:

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Top referenced anti-P2RX7 Antibodies

  1. Human Polyclonal P2RX7 Primary Antibody for IHC (p), WB - ABIN651861 : Kim, Jiang, Wilson, North, Surprenant: Proteomic and functional evidence for a P2X7 receptor signalling complex. in The EMBO journal 2001 (PubMed)
    Show all 2 references for ABIN651861

  2. Cow (Bovine) Polyclonal P2RX7 Primary Antibody for WB - ABIN2776151 : Al-Shukaili, Al-Kaabi, Hassan: A comparative study of interleukin-1beta production and p2x7 expression after ATP stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls. in Inflammation 2008 (PubMed)

  3. Dog (Canine) Polyclonal P2RX7 Primary Antibody for EIA, IHC (p) - ABIN401660 : Tomasinsig, Pizzirani, Skerlavaj, Pellegatti, Gulinelli, Tossi, Di Virgilio, Zanetti: The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner. in The Journal of biological chemistry 2008 (PubMed)

  4. Cow (Bovine) Polyclonal P2RX7 Primary Antibody for IHC, WB - ABIN2776335 : Buell, Talabot, Gos, Lorenz, Lai, Morris, Antonarakis: Gene structure and chromosomal localization of the human P2X7 receptor. in Receptors & channels 1999 (PubMed)

More Antibodies against P2RX7 Interaction Partners

Zebrafish Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. Blockade of the P2X7 receptor reduces cyst formation via ERK (show MAPK1 Antibodies)-dependent pathways in a zebrafish model of polycystic kidney disease.

Human Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. ATP release by Muller cells and P2X7 upregulation in RECs. These findings are likely of in vivo relevance since CD40 (show CD40 Antibodies) upregulates P2X7 in RECs in diabetic mice and CD40 (show CD40 Antibodies) is known to be required for retinal capillary degeneration.

  2. Our study revealed a significant association between three P2X7R gene polymorphisms and pulmonary tuberculosis in a Tibetan Chinese population.

  3. circadian oscillations of intracellular calcium depend on the activation of purinergic P2X7 receptors

  4. the biochemical and molecular knowledge of P2X7R in IFCD is useful to shed further light about the participation of purinergic system in the pathogenesis of CD, and consequently, may help to avoid the progression of disease.

  5. The P2X7R rs3751142 genetic variants was not implicated in the development of gout in the male Korean population. However, we found that in a pair-wise comparison of the CA/TT P2X7R and CARD8 (show CARD8 Antibodies) genotype combination was shown to have an increased trend for the risk of gout.

  6. Five gene polymorphisms, -762C>T (rs2393799), 946G>A (rs28360457), 1513A>C (rs3751143), 1068G>A (rs1718119), and 1096C>G (rs2230911), were selected. Our results suggest that 3 of the 5 polymorphisms of P2RX7 described above (1513A>C, 946G>A, and 1068G>A) are significantly associated with Hepatocellular Carcinoma susceptibility in a Chinese Han population.

  7. a local Ca(2 (show CA2 Antibodies)+) signal near a fragment that encodes the intracellular P2X2R C-terminus tail is sufficient to trigger blebbing

  8. Overexpression of P2RX7 is associated with uveal melanoma.

  9. there is a relationship between the elevated expression of P2X3 (show P2RX3 Antibodies) receptor and P2X7 receptor in peripheral blood leukocytes and high serum epinephrine and norepinephrine levels in hyperthyroidism patients.

  10. a pivotal role of P2X7 receptor-pannexin-1 (show PANX1 Antibodies) in oxysterols toxicity in retinal cells

Cow (Bovine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. For the inflammasome-dependent IL-1beta (show IL1B Antibodies) release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta (show IL1B Antibodies) release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor.

Mouse (Murine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. In the brain samples, expressions of P2Y4 (show P2RY4 Antibodies) and P2X7 were significantly reduced, whereas that of P2Y1 (show P2RY1 Antibodies) was significantly elevated in an age-dependent manner.

  2. results suggest a neuronal activity-dependent P2X7R expression which is induced by the transcription factor Sp1 (show SP1 Antibodies) and repressed in a calcium-dependent manner by microRNA-22

  3. The data are consistent with the hypothesis that P2X7R contributes to alveolar epithelial barrier function through effects on GSK-3beta (show GSK3b Antibodies).

  4. These analyses revealed that TNAP (show ALPL Antibodies) deficient mice present an increased proliferation of neural precursors, an altered neuronal morphology, and an augmented neuronal activity. We found that these alterations were associated with a partial downregulation of the purinergic P2X7 receptor (P2X7R).

  5. We conclude that unstimulated P2X7 from J774 cells act as scavenger receptor for the uptake of S. aureus and E. coli but not of yeast; Ca(2 (show CA2 Antibodies)+) entry via P2X7 receptors play no role in phagocytosis of S. aureus and E. coli; while the effect of Ca(2 (show CA2 Antibodies)+) on C. glabrata phagocytosis was mediated by the adhesins Epa1, Epa6 (show Epha6 Antibodies) and Epa7.

  6. The mechanosensitive up-regulation and release of cytokine IL-6 (show IL6 Antibodies) from the retina involves the P2X7 receptor, with both astrocytes and neurons contributing to the response

  7. lncRNA A30P01019163 may affect ovarian cell cycle and proliferation by regulating P2rx7 expression in the ovary.

  8. both synergic and additive relationships are found within P2X7, cationic, and anionic large pores

  9. P2X7R stimulation in macrophages is able to release potent anti-inflammatory proteins, such as Annexin A1 (show ANXA1 Antibodies), independently of their polarization state suggesting for first time a potential role for P2X7R during resolution of the inflammation and not linked to the release of pro-inflammatory cytokines.

  10. These results indicate that activation of Panx1 (show PANX1 Antibodies) and P2X7 R are required for apoptotic osteocytes in fatigued bone to trigger RANKL (show TNFSF11 Antibodies) production in neighboring bystander osteocytes and implicate ATP as an essential signal mediating this process.

P2RX7 Antigen Profile

Antigen Summary

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.

Alternative names and synonyms associated with P2RX7

  • purinergic receptor P2X, ligand-gated ion channel, 7 (P2RX7) antibody
  • purinergic receptor P2X, ligand-gated ion channel, 7 (p2rx7) antibody
  • purinergic receptor P2X, ligand-gated ion channel, 7 (P2rx7) antibody
  • AI467586 antibody
  • P2RX7 antibody
  • P2X(7) antibody
  • p2x7 antibody
  • P2X7R antibody
  • p2xr7 antibody

Protein level used designations for P2RX7

P2X purinoceptor 7 , purinergic receptor P2X, ligand-gated ion channel, 7 , p2X purinoceptor 7-like , ATP receptor , P2X7 receptor , P2Z receptor , purinergic receptor P2X7 variant A , P2X7 purinoceptor , purinergic receptor P2X7

100058464 Equus caballus
387298 Danio rerio
452318 Pan troglodytes
699455 Macaca mulatta
771952 Gallus gallus
100458463 Pongo abelii
100588362 Nomascus leucogenys
5027 Homo sapiens
448778 Canis lupus familiaris
286814 Bos taurus
18439 Mus musculus
29665 Rattus norvegicus
497623 Sus scrofa
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