P2RX7 antibody

Catalog No. ABIN2476002

There are 2+ publications for this product available. The Rat Monoclonal anti-P2RX7 antibody is suitable to detect P2RX7 in samples from Mouse. It has been validated for FACS and IF.

Quick Overview for P2RX7 antibody (ABIN2476002)

Target: P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This P2RX7 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: Hano43

Product Details anti-P2RX7 Antibody

Characteristics: Purified IgG

Purification: Purified

Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-P2RX7 antibody (ABIN2476002)

Adriouch, Bannas, Schwarz, Fliegert, Guse, Seman, Haag, Koch-Nolte: "ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 3, pp. 861-9, (2008) (PubMed).

Adriouch, Dubberke, Diessenbacher, Rassendren, Seman, Haag, Koch-Nolte: "Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 72-7, (2005) (PubMed).

Target Details for P2RX7

Target: P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))

Alternative Name: P2X7

Background: Synonyms: P2RX7

Gene ID: 18439

UniProt: Q9Z1M0

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis