Browse our anti-SP1 (SP1) Antibodies

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anti-Sp1 Transcription Factor Antibodies (SP1)
On are 286 Sp1 Transcription Factor (SP1) Antibodies from 29 different suppliers available. Additionally we are shipping SP1 Kits (25) and SP1 Proteins (9) and many more products for this protein. A total of 334 SP1 products are currently listed.
1110003E12Rik, AA450830, AI845540, fc18h09, SP1, Sp1-1, wu:fc18h09, zgc:85950

Most Popular Reactivities for anti-SP1 (SP1) Antibodies

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anti-Human SP1 Antibodies:

anti-Rat (Rattus) SP1 Antibodies:

anti-Mouse (Murine) SP1 Antibodies:

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Top referenced anti-SP1 Antibodies

  1. Human Polyclonal SP1 Primary Antibody for ChIP, WB - ABIN2668968 : Wang, Mayhew, Chen, Johnston, Mitra: "Calling cards" for DNA-binding proteins in mammalian cells. in Genetics 2012 (PubMed)
    Show all 6 references for 2668968

  2. Human Polyclonal SP1 Primary Antibody for EIA, FACS - ABIN954894 : Mucha, Ooi, Linley, Mordaka, Dalle, Robertson, Gamper, Wood: Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)
    Show all 5 references for 954894

  3. Human Polyclonal SP1 Primary Antibody for FACS, IF - ABIN655398 : Pan, Yang, Wei, Sun, Li: SP1 acts as a key factor, contributes to upregulation of ADAM23 expression under serum deprivation. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 4 references for 655398

  4. Human Polyclonal SP1 Primary Antibody for IHC (p), IP - ABIN153172 : Lay, Hong, Huang, Yang, Pao, Liu, Lai, Lai, Cheng, Su, Chuang: Sulfasalazine suppresses drug resistance and invasiveness of lung adenocarcinoma cells expressing AXL. in Cancer research 2007 (PubMed)
    Show all 3 references for 153172

  5. Human Monoclonal SP1 Primary Antibody for WB - ABIN1944791 : Takahara, Kanazu, Yanagisawa, Akanuma: Heterogeneous Sp1 mRNAs in human HepG2 cells include a product of homotypic trans-splicing. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for 1944791

  6. Human Polyclonal SP1 Primary Antibody for IF, IHC - ABIN1533004 : Kadonaga, Carner, Masiarz, Tjian: Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. in Cell 1988 (PubMed)

  7. Human Polyclonal SP1 Primary Antibody for ELISA, WB - ABIN185433 : Sakuntabhai, Turbpaiboon, Casadémont, Chuansumrit, Lowhnoo, Kajaste-Rudnitski, Kalayanarooj, Tangnararatchakit, Tangthawornchaikul, Vasanawathana, Chaiyaratana, Yenchitsomanus, Suriyaphol, Avirutnan et al.: A variant in the CD209 promoter is associated with severity of dengue disease. ... in Nature genetics 2005 (PubMed)

  8. Cow (Bovine) Polyclonal SP1 Primary Antibody for WB - ABIN2773827 : Yoshimura, Kimura, Ishii, Ishii, Matsuura, Geshi, Hosokawa, Muramatsu: Functional polymorphisms in carboxylesterase1A2 (CES1A2) gene involves specific protein 1 (Sp1) binding sites. in Biochemical and biophysical research communications 2008 (PubMed)

  9. Dog (Canine) Polyclonal SP1 Primary Antibody for WB - ABIN2779991 : Hsu, Chang, Hung: HER-2/neu represses the metastasis suppressor RECK via ERK and Sp transcription factors to promote cell invasion. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against SP1 Interaction Partners

Zebrafish Sp1 Transcription Factor (SP1) interaction partners

  1. A hierarchic gene expression of copper homeostatic genes was demonstrated between atp7a (show ATP7A Antibodies), sp1 and sod1 (show SOD1 Antibodies) in zebrafish.

  2. zebrafish Sp1-like protein is structurally and functionally comparable to human Sp1

Human Sp1 Transcription Factor (SP1) interaction partners

  1. The role of Sp1 (show PSG1 Antibodies) in colorectal cancer progression and metastasis was reviewed.

  2. the depleted beta-Arrestin1 (show ARRB1 Antibodies) reduced the interaction of P300 (show EP300 Antibodies) with Sp1 (show PSG1 Antibodies), thus to reduce Sp1 (show PSG1 Antibodies) binding to hTERT promoter, downregulate hTERT transcription, decrease telomerase activity, shorten telomere length, and promote Reh (show CES1 Antibodies) cell senescence.

  3. The Atgl (show PNPLA2 Antibodies) is down-regulated by the basal transcription factor Sp1 in preadipocytes and that the magnitude of down-regulation depends on interactions between Sp1 (show PSG1 Antibodies) and peroxisome proliferator-activated receptor gamma (PPARgamma (show PPARG Antibodies)).

  4. miR (show MLXIP Antibodies)-124 is a critical regulator in human aortic vascular smooth muscle cell differentiation, proliferation, and phenotype switch by targeting the 3'-untranslated region of specificity protein 1.

  5. Data indicate that DNMT3A (show DNMT3A Antibodies) allele G of rs1550117 was associated with an increased risk of non-small cell lung cancer (NSCLC) susceptibility and binding affinity of transcription repressor SP1 (show PSG1 Antibodies).

  6. Sp1 (show PSG1 Antibodies)-DNA binding affinity is reduced under Cu replete conditions but increased under reduced Cu conditions.

  7. Triptolide downregulates Sp1 (show PSG1 Antibodies) and HSP70 (show HSP70 Antibodies) mRNA in gastric cancer cell lines.

  8. Data indicate that interleukin 1alpha (IL-1alpha) propiece can activate NF-kappa B (NFkappaB (show NFKB1 Antibodies)) and Sp1 transcription factor (SP1).

  9. miR (show MLXIP Antibodies)-31-5p acted as a tumor suppressor to regulate SP1 (show PSG1 Antibodies), miR (show MLXIP Antibodies)-31-5p could be used as a therapeutic target for the treatment ofhepatocellular carcinoma.

  10. the overexpression of miR (show MLXIP Antibodies)-141 augments anoikis resistance in ovarian cancer cells by targeting and repressing the expression of KLF12 (show KLF12 Antibodies), which, in turn, competes for binding sites in the survivin (show BIRC5 Antibodies) promoter with Sp1 (show PSG1 Antibodies). The subsequent increase in survivin (show BIRC5 Antibodies) then protects ovarian cancer cells against anoikis by blocking the intrinsic apoptotic activity.

Cow (Bovine) Sp1 Transcription Factor (SP1) interaction partners

  1. study demonstrates the co-expression of DLX3 (show DLX3 Antibodies), PPARG (show PPARG Antibodies) and SP1 in trophoblast binucleated cell (BNC)nuclei; this suggests a possible role of these transcription factors through BNC specific genes at the time of pre-placental differentiation

  2. likely involvement of the Sp family in regulating PTH (show PTH Antibodies) gene expression through interactions with an Sp1 DNA element in the hormone's promoter.

  3. These results demonstrate that the single nucleotide polymorphism alters the bovine FASN (show FASN Antibodies) promoter activity in vitro and the Sp1/Sp3 binding ability of the sequence.

  4. The coordinate regulation of the bovine PRNP (show PRNP Antibodies) promoter suggests the two Sp1 binding site polymorphisms control Sp1 binding to the PRNP (show PRNP Antibodies) promoter and its activity.

Mouse (Murine) Sp1 Transcription Factor (SP1) interaction partners

  1. Results suggest that 25-hydroxycholesterol (25-HC) induced the interaction between NFATc1 (show NFATC1 Antibodies) and Sp1, reducing the level of free Sp1 to inhibit microRNA miR (show MLXIP Antibodies)-139-5p expression and promote osteoclastogenesis.

  2. data indicated that (-)-Epicatechin inhibited AngII-induced cardiac hypertrophy by activating the SP1/SIRT1 (show SIRT1 Antibodies) signaling pathway.

  3. This resulted in Sp1 displacement from the promoter and binding of Sp3 (show SP3 Antibodies) to it, leading to p300 (show NOTCH1 Antibodies) recruitment and histone acetylation, activating transcription. This is the first study addressing the mechanisms of physiological TLR5 (show TLR5 Antibodies) expression in the intestine. Additionally, a novel insight is gained into Sp1/Sp3 (show SP3 Antibodies)-mediated gene regulation that may apply to other genes

  4. adrenergic stimulation induced complex formation between Ifrd1 (show IFRD1 Antibodies), Sp1 and mSIN3B, which is a component of the SIN (show POLR3E Antibodies) complex containing histone deacetylase (show HDAC1 Antibodies), in brown adipocytes. These findings, therefore, suggest that Ifrd1 (show IFRD1 Antibodies) could be a pivotal negative regulator of sympathetic regulation of thermogenic and mitochondrial gene expression in brown adipocytes by interacting with Sp1 and the mSIN3 complex.

  5. Dp71 (show DMD Antibodies) expression in hepatic cells is carried out, in part, by YY1 (show YY1 Antibodies)-, Sp1- and Sp3 (show SP3 Antibodies)-mediated transcription from the Dp71 (show DMD Antibodies) promoter.

  6. SP1 expression was up-regulated in the tubular epithelial cells after acute kidney injury induced by ischemia-reperfusion.MiR-204 regulates epithelial-mesenchymal transition by targeting SP1 in the tubular epithelial cells.

  7. miR (show MLXIP Antibodies)-124, -128, and -137 act synergistically to regulate Sp1 expression.

  8. YY1 (show YY1 Antibodies) and SP1 independently and cooperatively govern the Mesp1 (show MESP1 Antibodies) expression during embryogenesis.

  9. Taken together, these results indicate that the transcription factor Sp1 upregulates the proximal promoter activity of the mouse Col11a1 (show COL11A1 Antibodies) gene in chondrocytes.

  10. In the initial stage of myocyte differentiation, transcription of the YB-1 (show YBX1 Antibodies) gene was regulated by E2F1 (show E2F1 Antibodies) and Sp1, and was then gradually replaced under the control of both MyoD (show MYOD1 Antibodies) and myogenin (show MYOG Antibodies).

SP1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SP1

  • sp1 transcription factor (sp1) antibody
  • Sp1 transcription factor (sp1) antibody
  • Sp1 transcription factor (SP1) antibody
  • Sp1 transcription factor (LOC100351317) antibody
  • Sp1 transcription factor (Sp1) antibody
  • trans-acting transcription factor 1 (Sp1) antibody
  • 1110003E12Rik antibody
  • AA450830 antibody
  • AI845540 antibody
  • fc18h09 antibody
  • SP1 antibody
  • Sp1-1 antibody
  • wu:fc18h09 antibody
  • zgc:85950 antibody

Protein level used designations for SP1

Sp1-like protein , transcription factor Sp1 , transcription factor , Sp1 transcription factor , transcription factor Sp1-like , specificity protein 1 , specific protein-1 , trans-acting transcription factor 1

324109 Danio rerio
394744 Xenopus (Silurana) tropicalis
451939 Pan troglodytes
702710 Macaca mulatta
100351317 Oryctolagus cuniculus
100407824 Callithrix jacchus
100440745 Pongo abelii
100474983 Ailuropoda melanoleuca
100553756 Anolis carolinensis
100585963 Nomascus leucogenys
6667 Homo sapiens
540741 Bos taurus
24790 Rattus norvegicus
397314 Sus scrofa
431939 Xenopus laevis
395303 Gallus gallus
486507 Canis lupus familiaris
100303456 Ovis aries
20683 Mus musculus
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