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Browse our anti-SP1 (SP1) Antibodies

Full name:
anti-Sp1 Transcription Factor Antibodies (SP1)
On www.antibodies-online.com are 276 Sp1 Transcription Factor (SP1) Antibodies from 28 different suppliers available. Additionally we are shipping SP1 Kits (22) and SP1 Proteins (9) and many more products for this protein. A total of 320 SP1 products are currently listed.
Synonyms:
1110003E12Rik, AA450830, AI845540, fc18h09, SP1, Sp1-1, wu:fc18h09, zgc:85950

Most Popular Reactivities for anti-SP1 (SP1) Antibodies

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anti-Human SP1 Antibodies:

anti-Rat (Rattus) SP1 Antibodies:

anti-Mouse (Murine) SP1 Antibodies:

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Top referenced anti-SP1 Antibodies

  1. Human Polyclonal SP1 Primary Antibody for EIA, FACS - ABIN954894 : Mucha, Ooi, Linley, Mordaka, Dalle, Robertson, Gamper, Wood: Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)
    Show all 5 references for ABIN954894

  2. Human Polyclonal SP1 Primary Antibody for ChIP, WB - ABIN2668968 : Wang, Mayhew, Chen, Johnston, Mitra: "Calling cards" for DNA-binding proteins in mammalian cells. in Genetics 2012 (PubMed)
    Show all 5 references for ABIN2668968

  3. Human Polyclonal SP1 Primary Antibody for FACS, IF - ABIN655398 : Pan, Yang, Wei, Sun, Li: SP1 acts as a key factor, contributes to upregulation of ADAM23 expression under serum deprivation. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 4 references for ABIN655398

  4. Human Monoclonal SP1 Primary Antibody for WB - ABIN1944791 : Takahara, Kanazu, Yanagisawa, Akanuma: Heterogeneous Sp1 mRNAs in human HepG2 cells include a product of homotypic trans-splicing. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for ABIN1944791

  5. Cow (Bovine) Polyclonal SP1 Primary Antibody for EIA, WB - ABIN374585 : Wan, Carr, Cutler, Lanza, Hines, Yost: Sp1 and Sp3 regulate basal transcription of the human CYP2F1 gene. in Drug metabolism and disposition: the biological fate of chemicals 2005 (PubMed)

  6. Cow (Bovine) Polyclonal SP1 Primary Antibody for WB - ABIN2779990 : Hsu, Chang, Hung: HER-2/neu represses the metastasis suppressor RECK via ERK and Sp transcription factors to promote cell invasion. in The Journal of biological chemistry 2006 (PubMed)

  7. Human Polyclonal SP1 Primary Antibody for IF, IHC - ABIN1533004 : Kadonaga, Carner, Masiarz, Tjian: Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. in Cell 1988 (PubMed)

  8. Human Polyclonal SP1 Primary Antibody for ELISA, WB - ABIN185433 : Sakuntabhai, Turbpaiboon, Casadémont, Chuansumrit, Lowhnoo, Kajaste-Rudnitski, Kalayanarooj, Tangnararatchakit, Tangthawornchaikul, Vasanawathana, Chaiyaratana, Yenchitsomanus, Suriyaphol, Avirutnan et al.: A variant in the CD209 promoter is associated with severity of dengue disease. ... in Nature genetics 2005 (PubMed)

  9. Chicken Polyclonal SP1 Primary Antibody for WB - ABIN2773827 : Yoshimura, Kimura, Ishii, Ishii, Matsuura, Geshi, Hosokawa, Muramatsu: Functional polymorphisms in carboxylesterase1A2 (CES1A2) gene involves specific protein 1 (Sp1) binding sites. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against SP1 Interaction Partners

Zebrafish Sp1 Transcription Factor (SP1) interaction partners

  1. A hierarchic gene expression of copper homeostatic genes was demonstrated between atp7a (show ATP7A Antibodies), sp1 and sod1 (show SOD1 Antibodies) in zebrafish.

  2. zebrafish Sp1-like protein is structurally and functionally comparable to human Sp1

Human Sp1 Transcription Factor (SP1) interaction partners

  1. these findings show that SP1 (show PSG1 Antibodies)-activated LINC00673 exerts an oncogenic function that promotes GC development and progression, at least in part, by functioning as a scaffold for LSD1 (show KDM1A Antibodies) and EZH2 (show EZH2 Antibodies) and repressing KLF2 (show KLF2 Antibodies) and LATS2 (show LATS2 Antibodies) expression.

  2. During LPS (show IRF6 Antibodies) induced macrophage inflammatory response, PHLPP (show PHLPP1 Antibodies) levels in macrophages are depleted through the inhibition of SP1 (show PSG1 Antibodies) dependent transcriptional regulation.

  3. The mRNA levels of ACSL1 (show Acsl1 Antibodies) were positively associated with those of HBXIP (show HBXIP Antibodies) in clinical breast cancer tissues. Thus, we conclude that the oncoprotein HBXIP (show HBXIP Antibodies) is able to up-regulate ACSL1 (show Acsl1 Antibodies) through activating the transcriptional factor Sp1 (show PSG1 Antibodies) in breast cancer.

  4. hTERT facilitates tumor angiogenesis by up-regulating VEGF (show VEGFA Antibodies) expression through direct interactions with the VEGF (show VEGFA Antibodies) gene and the Sp1 transcription factor.

  5. Using mass spectrometry and site directed mutagenesis, a new Sp1 (show PSG1 Antibodies) phosphorylation site Ser702 was defined to be associated with Sp1 (show PSG1 Antibodies)-HDAC1 (show HDAC1 Antibodies) interaction and may be important in SR-BI (show SCARB1 Antibodies) activation, shedding light on the knowledge of delicate mechanism of hepatic HDL (show HSD11B1 Antibodies) receptor SR-BI (show SCARB1 Antibodies) gene modulation by LDL.

  6. Results show that hyperglycemia-induced upregulation of Robo4 (show ROBO4 Antibodies) in retinal endothelial cells is directly mediated by transcription factor SP1 which increases the transcription of Robo4 (show ROBO4 Antibodies) via an additional binding site in Robo4 (show ROBO4 Antibodies) promoter. SP1 (show PSG1 Antibodies)/Robo4 (show ROBO4 Antibodies) can regulate the migration, monolayer permeability and angiogenesis of retinal endothelial cells under hyperglycemic conditions.

  7. these findings highlight the epigenetic regulation of MIOX (show MIOX Antibodies) in the pathogenesis of diabetic tubulopathy.

  8. decreased expression of transcription factor Sp1 contributes to suppression of SHIP2 (show INPPL1 Antibodies) in gastric cancer cells.

  9. this study shows that IL-10 (show IL10 Antibodies) production by CD20 (show MS4A1 Antibodies)+ B cells among peripheral blood mononuclear cell is enhanced by bendamustine via p38 MAP kinase (show MAPK14 Antibodies)-Sp1 (show PSG1 Antibodies) pathway

  10. During inflammatory conditions, AP-1 (show FOSB Antibodies) and Sp1 (show PSG1 Antibodies) sustained the expression of ADAMTS7 (show ADAMTS7 Antibodies), and ADAMTS7 (show ADAMTS7 Antibodies) sustained the expression of catabolic genes in nucleus pulposus cells

Cow (Bovine) Sp1 Transcription Factor (SP1) interaction partners

  1. study demonstrates the co-expression of DLX3 (show DLX3 Antibodies), PPARG (show PPARG Antibodies) and SP1 in trophoblast binucleated cell (BNC)nuclei; this suggests a possible role of these transcription factors through BNC specific genes at the time of pre-placental differentiation

  2. likely involvement of the Sp family in regulating PTH (show PTH Antibodies) gene expression through interactions with an Sp1 DNA element in the hormone's promoter.

  3. These results demonstrate that the single nucleotide polymorphism alters the bovine FASN (show FASN Antibodies) promoter activity in vitro and the Sp1/Sp3 binding ability of the sequence.

  4. The coordinate regulation of the bovine PRNP (show PRNP Antibodies) promoter suggests the two Sp1 binding site polymorphisms control Sp1 binding to the PRNP (show PRNP Antibodies) promoter and its activity.

Mouse (Murine) Sp1 Transcription Factor (SP1) interaction partners

  1. Dp71 (show DMD Antibodies) expression in hepatic cells is carried out, in part, by YY1 (show YY1 Antibodies)-, Sp1- and Sp3 (show SP3 Antibodies)-mediated transcription from the Dp71 (show DMD Antibodies) promoter.

  2. SP1 expression was up-regulated in the tubular epithelial cells after acute kidney injury induced by ischemia-reperfusion.MiR-204 regulates epithelial-mesenchymal transition by targeting SP1 in the tubular epithelial cells.

  3. miR (show MLXIP Antibodies)-124, -128, and -137 act synergistically to regulate Sp1 expression.

  4. YY1 (show YY1 Antibodies) and SP1 independently and cooperatively govern the Mesp1 (show MESP1 Antibodies) expression during embryogenesis.

  5. Taken together, these results indicate that the transcription factor Sp1 upregulates the proximal promoter activity of the mouse Col11a1 (show COL11A1 Antibodies) gene in chondrocytes.

  6. In the initial stage of myocyte differentiation, transcription of the YB-1 (show YBX1 Antibodies) gene was regulated by E2F1 (show E2F1 Antibodies) and Sp1, and was then gradually replaced under the control of both MyoD (show MYOD1 Antibodies) and myogenin (show MYOG Antibodies).

  7. Data indicate that Sp1 and AP-1 (show JUN Antibodies)-related factors are involved in the regulation of MFG-E8 (show MFGE8 Antibodies) gene transcription by targeting their binding sites in the 5'-flanking region under physiological and inflammatory states.

  8. Our results unveil strikingly different recruitment mechanisms of Sp1/Sp2/Sp3 transcription factor (show SP3 Antibodies) members uncovering an unexpected layer of complexity in their binding to chromatin in vivo.

  9. age-dependent alteration in the Fmr-1 (show FMR1 Antibodies) gene expression is associated with Sp1 interaction with Fmr-1 (show FMR1 Antibodies) promoter which in turn might be related with cognitive development during brain maturation and aging.

  10. The results of this study suggest that SP4 and SP1 upregulation may be part of the mechanisms deregulated downstream of glutamate (show GRIN1 Antibodies) signalling pathways in schizophrenia

SP1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SP1

  • sp1 transcription factor (sp1) antibody
  • Sp1 transcription factor (sp1) antibody
  • Sp1 transcription factor (SP1) antibody
  • Sp1 transcription factor (LOC100351317) antibody
  • Sp1 transcription factor (Sp1) antibody
  • trans-acting transcription factor 1 (Sp1) antibody
  • 1110003E12Rik antibody
  • AA450830 antibody
  • AI845540 antibody
  • fc18h09 antibody
  • SP1 antibody
  • Sp1-1 antibody
  • wu:fc18h09 antibody
  • zgc:85950 antibody

Protein level used designations for SP1

Sp1-like protein , transcription factor Sp1 , transcription factor , Sp1 transcription factor , transcription factor Sp1-like , specificity protein 1 , specific protein-1 , trans-acting transcription factor 1

GENE ID SPECIES
324109 Danio rerio
394744 Xenopus (Silurana) tropicalis
451939 Pan troglodytes
702710 Macaca mulatta
100351317 Oryctolagus cuniculus
100407824 Callithrix jacchus
100440745 Pongo abelii
100474983 Ailuropoda melanoleuca
100553756 Anolis carolinensis
100585963 Nomascus leucogenys
6667 Homo sapiens
540741 Bos taurus
24790 Rattus norvegicus
397314 Sus scrofa
431939 Xenopus laevis
395303 Gallus gallus
486507 Canis lupus familiaris
100303456 Ovis aries
20683 Mus musculus
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