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Browse our DDIT3 (DDIT3) ELISA Kits

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DNA-Damage-Inducible Transcript 3 ELISA Kits (DDIT3)
On are 32 DNA-Damage-Inducible Transcript 3 (DDIT3) ELISA Kits from 9 different suppliers available. Additionally we are shipping DDIT3 Antibodies (197) and DDIT3 Proteins (19) and many more products for this protein. A total of 262 DDIT3 products are currently listed.
CEBPZ, CHOP, CHOP-10, Chop10, GADD153, Xchop
list all ELISA KIts Gene Name GeneID UniProt
DDIT3 13198 P35639
DDIT3 29467  
DDIT3 1649 P35638

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More ELISA Kits for DDIT3 Interaction Partners

Mouse (Murine) DNA-Damage-Inducible Transcript 3 (DDIT3) interaction partners

  1. Study showed that Chop is involved in the pathogenesis of pulmonary fibrosis by regulating the generation of M2 macrophages and TGF-beta (show TGFB1 ELISA Kits) signaling.

  2. AMPKalpha1 (show PRKAA1 ELISA Kits) mediates CHOP ubiquitination and proteasomal degradation in macrophages by promoting the phosphorylation of CHOP at serine 30. Transfection of Chop-specific siRNA but not control siRNA reduced both CHOP level and injury-induced neointimal disruption in vivo.

  3. The data presented indicate that the unfolded protein response is activated in fibrotic lung tissue and strongly localized to macrophages. GRP78 (show HSPA5 ELISA Kits)- and CHOP-mediated macrophage apoptosis was found to protect against bleomycin-induced fibrosis.

  4. Deletion of CHOP attenuates dysfunction of the autophagy/lysosomal pathway in beta-cells of transgenic mice.

  5. Interference with DOT1L activity resulted in transcriptional activation of Atf4 (show ATF4 ELISA Kits) and Ddit3 accompanied by decreased levels of H3K79 dimethylation.

  6. this study demonstrates novel roles for the endoplasmic reticulum stress-response transducer PERK (show EIF2AK3 ELISA Kits) and a downstream effector of its activation, CHOP, in tubule cell production of fibronectin (show FN1 ELISA Kits)

  7. CHOP regulates not only apoptosis-related signaling but also ROS (show ROS1 ELISA Kits) formation and inflammation in renal tubular cells during ischemia/reperfusion (I/R). CHOP may play an important role in the pathophysiology of I/R-induced renal injury.

  8. As a dual function cytokine, IL-1alpha may contribute to the induction of CHOP intracellularly, while IL-1alpha released from necrotic cells accelerates steatohepatitis via induction of inflammatory cytokines by neighboring cells.

  9. TFEB-regulated signaling pathway for osteoblast differentiation is involved in ATF4 (show ATF4 ELISA Kits)/CHOP-dependent signaling pathway.

  10. CHOP expression in myeloid cells plays an important role in determining the magnitude and duration of inflammatory response in vivo by modulating expression of proinflammatory cytokines such as IL-6 (show IL6 ELISA Kits) in infiltrating macrophages.

Human DNA-Damage-Inducible Transcript 3 (DDIT3) interaction partners

  1. CHOP protects hepatocytes from a diet high in fat, fructose, and cholesterol (HFCD) and its induced ER stress, and has a significant role in the mechanism of liraglutide-mediated protection against non-alcoholic steatohepatitis (NASH (show SAMSN1 ELISA Kits)) pathogenesis.

  2. Study showed that Chop is involved in the pathogenesis of pulmonary fibrosis by regulating the generation of M2 macrophages and TGF-beta (show TGFB1 ELISA Kits) signaling.

  3. Downregulation of CHOP by small interfering RNA somewhat restored expression of AR suggesting that AR degradation is dependent on ER stress pathway. Future studies will need to evaluate other aspects of the unfolded protein response pathway to characterize the regulation of AR degradation

  4. Herein, the authors extend their previous research and provide evidence that ORF57 of human herpesvirus-8 interacts with CHTOP (show CHTOP ELISA Kits) and CIP29 (show SARNP ELISA Kits), in contrast to POLDIP3 (show POLDIP3 ELISA Kits).

  5. NAG-1 (show GDF15 ELISA Kits) expression was transcriptionally upregulated by CHOP, which promoted chemokine (show CCL1 ELISA Kits) production through sustained NF-kappaB (show NFKB1 ELISA Kits) activation.

  6. plasma exposure resulted in expression of unfolded protein response (UPR) proteins such as glucoserelated protein 78 (GRP78 (show HSPA5 ELISA Kits)), protein kinase (show CDK7 ELISA Kits) R (PKR (show PKLR ELISA Kits))like ER kinase (PERK (show EIF2AK3 ELISA Kits)), and inositolrequiring enzyme 1 (IRE1 (show ERN1 ELISA Kits)). Elevated expression of spliced Xbox binding protein 1 (XBP1 (show XBP1 ELISA Kits)) and CCAAT/enhancerbinding protein homologous protein (CHOP) further confirmed that ROS (show ROS1 ELISA Kits) generatedby NTGP induces apoptosis through the ER stress

  7. High DDIT3 expression is associated with non-small-cell lung cancer.

  8. CAPE/TRAIL stimulated apoptosis through the binding of TRAIL to DR5 (show TNFRSF10B ELISA Kits). Moreover, expression of transcription factor C/EBP homologous protein (CHOP) markedly increased in response to CAPE and transient knockdown of CHOP abolished CAPE/TRAIL-mediated apoptosis.

  9. the C/EBPD (show CEBPD ELISA Kits) binding site is required for RU486-mediated activation of the CHOP promoter.

  10. Data show CGK733 induced microtubule associated protein LC3B (show MAP1LC3B ELISA Kits) formation upstream of AMP-activated protein kinase (show PRKAA2 ELISA Kits) and protein kinase (show CDK7 ELISA Kits) RNA-like endoplasmic reticulum kinase/CCAAT-enhancer-binding protein homologous protein pathways and p21 Cip1 (show CDKN1A ELISA Kits) expression.

Xenopus laevis DNA-Damage-Inducible Transcript 3 (DDIT3) interaction partners

  1. CHOP (GADD153) is an inhibitor of Wnt (show WNT2 ELISA Kits)/TCF (show HNF4A ELISA Kits) signals

DDIT3 Antigen Profile

Antigen Summary

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

Alternative names and synonyms associated with DDIT3

  • DNA-damage-inducible transcript 3 (ddit3) Elisa Kit
  • DNA-damage inducible transcript 3 (Ddit3) Elisa Kit
  • DNA-damage-inducible transcript 3 (DDIT3) Elisa Kit
  • DNA-damage-inducible transcript 3 (Ddit3) Elisa Kit
  • DNA-damage-inducible transcript 3 (LOC100338439) Elisa Kit
  • CEBPZ Elisa Kit
  • CHOP Elisa Kit
  • CHOP-10 Elisa Kit
  • Chop10 Elisa Kit
  • GADD153 Elisa Kit
  • Xchop Elisa Kit

Protein level used designations for DDIT3

C/EBP homoologous protein 10 , C/EBP zeta , CCAAT/enhancer-binding protein homologous protein , DDIT-3 , DNA damage-inducible transcript 3 protein , c/EBP-homologous protein 10 , growth arrest and DNA-damage-inducible protein GADD153 , C/EBP homologous protein , growth arrest and DNA damage-inducible protein GADD153 , growth arrest and DNA damage-inducible , transcription factor GADD153 , C/EBP-homologous protein 10 , DNA-damage inducible transcript 3

733816 Xenopus (Silurana) tropicalis
13198 Mus musculus
29467 Rattus norvegicus
1649 Homo sapiens
398615 Xenopus laevis
777788 Bos taurus
607439 Canis lupus familiaris
100857832 Gallus gallus
101787388 Cavia porcellus
100240743 Sus scrofa
100338439 Oryctolagus cuniculus
541600 Ovis aries
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