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Browse our Dicer 1, Ribonuclease Type III Proteins (DICER1)

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Dicer 1, Ribonuclease Type III Proteins (DICER1)
On are 3 Dicer 1, Ribonuclease Type III (DICER1) Proteins from 2 different suppliers available. Additionally we are shipping Dicer 1, Ribonuclease Type III Antibodies (122) and Dicer 1, Ribonuclease Type III Kits (9) and many more products for this protein. A total of 135 Dicer 1, Ribonuclease Type III products are currently listed.
1110006F08Rik, D12Ertd7e, DCR1, DICER, dicer1, fc39d11, fc74b05, HERNA, mKIAA0928, MNG1, wu:fc39d11, wu:fc74b05
list all proteins Gene Name GeneID UniProt
Mouse DICER1 DICER1 192119  
DICER1 23405 Q9UPY3
Rat DICER1 DICER1 299284  

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Dicer 1, Ribonuclease Type III Proteins (DICER1) by Origin

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More Proteins for Dicer 1, Ribonuclease Type III Interaction Partners

Mouse (Murine) Dicer 1, Ribonuclease Type III (DICER1) interaction partners

  1. Study suggested that loss of Gli2 mRNA mediated the anterior-restricted defect in conditional Dicer knockdown mice and showed that miR-106b positively regulated Gli2 mRNA expression

  2. these findings indicate that Dicer1-dependent generation of mature miRNAs in late-stage MKs (show MKKS Proteins) and platelets modulates the expression of target mRNAs important for the hemostatic and thrombotic function of platelets.

  3. reveal Dicer1-miR (show MLXIP Proteins)-328-Bace1 (show BACE Proteins) signalling as a determinant of brown adipose tissue function

  4. Dicer promotes endothelial maladaptation and atherosclerosis in part by miR (show MLXIP Proteins)-103-mediated suppression of KLF4 (show KLF4 Proteins).

  5. Suggest recurrent DICER1 hotspot mutations in endometrial tumours impact on microRNA biogenesis.

  6. data indicate that oocyte DICER expression in the fetal ovary is required, and oocyte DROSHA (show DROSHA Proteins) is dispensable, for postnatal follicular development and female fertility in adulthood.

  7. Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia.

  8. These studies identify FGF9 as a target of DICER1 in lung epithelium that functions as an initiating factor for pleuropulmonary blastoma.

  9. DICER-null beta-cells demonstrated that Fcgrt (show FCGRT Proteins), Oat (show OAT Proteins), and Pdgfra (show PDGFRA Proteins) are miRNA direct targets.

  10. Hepatic loss of Dicer1 results in complex chronic pathological processes, including hepatocyte death, inflammatory infiltration, chronic fibrosis, compensatory proliferation, progenitor activation, and spontaneous hepatocarcinogenesis.

Human Dicer 1, Ribonuclease Type III (DICER1) interaction partners

  1. Our results suggest that DICER1 mutations may not have a role in testicular sex cord-stromal tumorigenesis

  2. An essential role of Dicer in microRNA biogenesis

  3. this study proposes that inflammation-induced Jak-STAT3 signaling leads to colon cancer development through proteasomal degradation of DICER1 by ubiquitin ligase complex of CUL4A(DCAF1), which suggests a novel therapeutic opportunity for colon cancer

  4. Our data suggest that reduced Dicer expression might contribute to tumour progression in colorectal cancer

  5. DICER1 and DROSHA (show DROSHA Proteins) copy number variation may be an important mechanism of upregulation/downregulation of miRNAs in lung cancer

  6. Polymorphisms of rs3742330 of the DICER gene, particularly the AA genotype, may be associated with azoospermia.

  7. A weak DICER1 protein expression was associated with reduced disease-free and overall survival and was a predictor of recurrence in adrenocortical carcinomas.

  8. This work identifies Dicer regulation as both a potential mediator of MS pathology and a therapeutic target.

  9. Expression of DICER1 and microRNA are reduced in post-traumatic stress disorder with comorbid depression.

  10. Data indicate an association between DICER1 hotspot mutations and altered expression of cell growth and development genes.

Pig (Porcine) Dicer 1, Ribonuclease Type III (DICER1) interaction partners

  1. Diminished androgen action during gestation induces changes in Dicer1 mRNA expression.

  2. The primary cDNA sequence of porcine Dicer was determined, and its expression in porcine oocytes and early stage embryos was confirmed.

Cow (Bovine) Dicer 1, Ribonuclease Type III (DICER1) interaction partners

  1. Studied Dicer gene expression during early bovine embryo development.An increase in Dicer expression was detected in the mature oocytes sampled (P<0.05), implying that gene repression occurs during meiosis II.

Zebrafish Dicer 1, Ribonuclease Type III (DICER1) interaction partners

  1. Dynamic miRNA expression patterns during retinal regeneration in zebrafish: reduced dicer or miRNA expression suppresses proliferation of Muller glia-derived neuronal progenitor cells

Dicer 1, Ribonuclease Type III (DICER1) Protein Profile

Protein Summary

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Dicer 1, Ribonuclease Type III (DICER1)

  • dicer 1, ribonuclease type III (DICER1)
  • endoribonuclease Dicer (CpipJ_CPIJ010534)
  • dicer 1, ribonuclease type III (dicer1)
  • double-stranded RNA-specific endoribonuclease type III (dicer1)
  • dicer 1, ribonuclease type III (Dicer1)
  • Dicer1, Dcr-1 homolog (Drosophila) (dicer1)
  • 1110006F08Rik protein
  • D12Ertd7e protein
  • DCR1 protein
  • DICER protein
  • dicer1 protein
  • fc39d11 protein
  • fc74b05 protein
  • HERNA protein
  • mKIAA0928 protein
  • MNG1 protein
  • wu:fc39d11 protein
  • wu:fc74b05 protein

Protein level used designations for DICER1

Dicer1, Dcr-1 homolog , endoribonuclease Dicer , dicer 1, ribonuclease type III , double-stranded RNA-specific endoribonuclease type III , double-strand-specific ribonuclease mDCR-1 , K12H4.8-LIKE , dicer 1, double-stranded RNA-specific endoribonuclease , helicase MOI , helicase with RNAse motif , helicase-moi , dicer , dsRNA-specific ribonuclease

453137 Pan troglodytes
480426 Canis lupus familiaris
702516 Macaca mulatta
6043055 Culex quinquefasciatus
100065648 Equus caballus
100170154 Xenopus (Silurana) tropicalis
100227750 Taeniopygia guttata
100316917 Xenopus laevis
192119 Mus musculus
23405 Homo sapiens
299284 Rattus norvegicus
100505387 Sus scrofa
337871 Bos taurus
423437 Gallus gallus
100689239 Cricetulus griseus
324724 Danio rerio
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