Browse our Dicer 1, Ribonuclease Type III Proteins (DICER1)

Full name:
Dicer 1, Ribonuclease Type III Proteins (DICER1)
On www.antibodies-online.com are 4 Dicer 1, Ribonuclease Type III (DICER1) Proteins from 3 different suppliers available. Additionally we are shipping Dicer 1, Ribonuclease Type III Antibodies (166) and Dicer 1, Ribonuclease Type III Kits (13) and many more products for this protein. A total of 184 Dicer 1, Ribonuclease Type III products are currently listed.
Synonyms:
1110006F08Rik, D12Ertd7e, DCR1, DICER, dicer1, fc39d11, fc74b05, HERNA, mKIAA0928, MNG1, wu:fc39d11, wu:fc74b05
list all proteins Gene Name GeneID UniProt
Mouse DICER1 DICER1 192119  
DICER1 23405 Q9UPY3
Rat DICER1 DICER1 299284  

Show all synonyms

Dicer 1, Ribonuclease Type III Proteins (DICER1) by Origin

Select your origin of interest

Top referenced Dicer 1, Ribonuclease Type III Proteins

  1. Human DICER1 Protein expressed in HEK-293 Cells - ABIN2719477 : Zhang, Li, Deng, Liu, Chen, Tang, Wang, Cao, Fang, Wen, Xu, Chen, Shi, Li, Xie, Tang: Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents. in Nucleic acids research 2016 (PubMed)

More Proteins for Dicer 1, Ribonuclease Type III Interaction Partners

Mouse (Murine) Dicer 1, Ribonuclease Type III (DICER1) interaction partners

  1. Dicer1 ablation impairs Shh-induced granule neuron precursor proliferation by disrupting the expression of distinct cell cycle regulator genes that are targets of miR-17 approximately 92 cluster members. This study establishes a molecular link between miRNAs and cell cycle progression in the proliferating Granule neuron precursors during normal cerebellar development and may facilitate miRNA application in treating med...

  2. Dicer maintains the identity and function of proprioceptive sensory neurons. Results suggest that Dicer and, most likely by extension, microRNAs are crucially important for maintaining proprioception. Additionally, this study hints at the larger question of how neurons maintain their functional and molecular specificity.

  3. this study shows that Dicer deficiency differentially impacts microglia of the developing and adult brain

  4. this study shows that deletion Dicer1 specifically in Th17 cells protected mice from experimental autoimmune encephalomyelitis

  5. Dicer expression in smooth muscle cells plays an essential role in vascular repair by generating anti-proliferative miRNAs.

  6. The findings of this study further substantiate the important role of DICER1 in the maintenance of homeostasis and the regulation of inflammatory responses

  7. The paracrine control of functions important to post-testicular sperm maturation by Dicer1-dependent factors may open new avenues for the identification of molecular targets important to male fertility control.

  8. Dicer1-deficient NK cells failed to complete their differentiation program; Dicer1 deletion impaired key NK-cell functions: target cell killing and production of IFN-gamma (show IFNG Proteins)

  9. that DICER/Let-7 activity opposes IFN-gamma-induced (show SAMHD1 Proteins), immunostimulatory M1-like tumour-associated macrophage activation, with potential therapeutic implications

  10. In Dicer-deficient mice Orai1 (show TMEM132A Proteins) was down-regulated at mRNA and protein level in CD4 (show CD4 Proteins)+ T cells.

Human Dicer 1, Ribonuclease Type III (DICER1) interaction partners

  1. Despite exhibiting an immunophenotype characteristic of a sex cord-stromal tumor, mutations in FOXL2 (show FOXL2 Proteins) and DICER1, the 2 most common mutations hitherto reported in ovarian sex cord-stromal tumors, are not a feature of Uterine tumor resembling ovarian sex cord tumor (UTROSCT).

  2. Place Dicer within the context of the DNA damage response by demonstrating a DNA damage-inducible phosphoswitch that causes localized processing of nuclear dsRNA by p-Dicer to promote DNA repair.

  3. In response to UV irradiation, DICER is recruited to chromatin in a ZRF1 (show DNAJC2 Proteins)-mediated manner. The H2A-ubiquitin binding protein ZRF1 (show DNAJC2 Proteins) and DICER together impact on the chromatin conformation via PARP1 (show PARP1 Proteins).

  4. We investigated the frequency of DICER1 mutations in a series of 38 ovarian tumors initially diagnosed as Sertoli-Leydig cell tumors, and explored whether identified mutations were associated with specific morphologic features

  5. Case Report: metachronous anaplastic sarcoma of the kidney and thyroid follicular carcinoma with DICER1 mutations.

  6. Dicer expression in smooth muscle cells plays an essential role in vascular repair by generating anti-proliferative miRNAs.

  7. a clear mechanistic link between hypoxia and tumor progression via upregulation of miR (show MLXIP Proteins)-630 and downregulation of Dicer.

  8. DICER1 hotspot mutations are closely associated with androgenic effects in ovarian Sertoli-Leydig cell tumors.

  9. We show that deleterious DICER1 mutations underlie the genetic basis of only a small fraction of sarcomas, in particular rhabdomyosarcoma of the urogenital tract.

  10. If Dicer becomes more clinically relevant as a prognostic indicator in breast cancer, further antibody optimization and standardization will be critical.

Pig (Porcine) Dicer 1, Ribonuclease Type III (DICER1) interaction partners

  1. Diminished androgen action during gestation induces changes in Dicer1 mRNA expression.

  2. The primary cDNA sequence of porcine Dicer was determined, and its expression in porcine oocytes and early stage embryos was confirmed.

Cow (Bovine) Dicer 1, Ribonuclease Type III (DICER1) interaction partners

  1. Studied Dicer gene expression during early bovine embryo development.An increase in Dicer expression was detected in the mature oocytes sampled (P<0.05), implying that gene repression occurs during meiosis II.

Zebrafish Dicer 1, Ribonuclease Type III (DICER1) interaction partners

  1. Dynamic miRNA expression patterns during retinal regeneration in zebrafish: reduced dicer or miRNA expression suppresses proliferation of Muller glia-derived neuronal progenitor cells

Dicer 1, Ribonuclease Type III (DICER1) Protein Profile

Protein Summary

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Dicer 1, Ribonuclease Type III (DICER1)

  • dicer 1, ribonuclease type III (DICER1)
  • endoribonuclease Dicer (CpipJ_CPIJ010534)
  • dicer 1, ribonuclease type III (dicer1)
  • double-stranded RNA-specific endoribonuclease type III (dicer1)
  • dicer 1, ribonuclease type III (Dicer1)
  • Dicer1, Dcr-1 homolog (Drosophila) (dicer1)
  • 1110006F08Rik protein
  • D12Ertd7e protein
  • DCR1 protein
  • DICER protein
  • dicer1 protein
  • fc39d11 protein
  • fc74b05 protein
  • HERNA protein
  • mKIAA0928 protein
  • MNG1 protein
  • wu:fc39d11 protein
  • wu:fc74b05 protein

Protein level used designations for DICER1

Dicer1, Dcr-1 homolog , endoribonuclease Dicer , dicer 1, ribonuclease type III , double-stranded RNA-specific endoribonuclease type III , double-strand-specific ribonuclease mDCR-1 , K12H4.8-LIKE , dicer 1, double-stranded RNA-specific endoribonuclease , helicase MOI , helicase with RNAse motif , helicase-moi , dicer , dsRNA-specific ribonuclease

GENE ID SPECIES
453137 Pan troglodytes
480426 Canis lupus familiaris
702516 Macaca mulatta
6043055 Culex quinquefasciatus
100065648 Equus caballus
100170154 Xenopus (Silurana) tropicalis
100227750 Taeniopygia guttata
100316917 Xenopus laevis
192119 Mus musculus
23405 Homo sapiens
299284 Rattus norvegicus
100505387 Sus scrofa
337871 Bos taurus
423437 Gallus gallus
100689239 Cricetulus griseus
324724 Danio rerio
Selected quality suppliers for Dicer 1, Ribonuclease Type III Proteins (DICER1)
Did you look for something else?