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DIO3 Proteins

(Deiodinase, Iodothyronine, Type III (DIO3))
The protein encoded by this intronless gene belongs to the iodothyronine deiodinase family. It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. This enzyme is highly expressed in the pregnant uterus, placenta, fetal and neonatal tissues, suggesting that it plays an essential role in the regulation of thyroid hormone inactivation during embryological development. This protein contains a selenocysteine (Sec) residue, which is essential for efficient enzyme activity. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008].
DIO3 Protein (AA 1-143) (GST tag) DIO3 Protein (AA 1-143) (GST tag) DIO3 Protein (AA 1-143) (GST tag) (ABIN1777658)

DIO3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

DIO3 Protein (AA 43-143) (GST tag) DIO3 Protein (AA 43-143) (GST tag) DIO3 Protein (AA 43-143) (GST tag) (ABIN1351611)

DIO3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

DIO3 Protein (AA 68-304) (His tag) DIO3 Protein (AA 68-304) (His tag) DIO3 Protein (AA 68-304) (His tag) (ABIN3081961)

Crystallography grade DIO3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

DIO3 Proteins by Grade

Find DIO3 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

DIO3 Proteins by Origin

Find DIO3 Proteins for a variety of species such as anti-Human DIO3, anti-Mouse DIO3, anti-Rat DIO3. The species listed below are among those available. Click on a link to go to the corresponding products.

DIO3 Proteins by Source

Here you will find DIO3 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

DIO3 Proteins by Protein Type

Here you can find DIO3 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

DIO3 Proteins by Application

Find DIO3 Proteins validated for a specific application such as ELISA, SDS, WB, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular DIO3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1777658
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351611
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3081961
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3127568
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3113970
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3127567
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398734
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398737
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
  • (1)
Cat. No. ABIN7479482
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
  • (1)
Cat. No. ABIN5714130
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5710946
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6120593
Quantity 100 μg
Datasheet Datasheet
Reactivity Bream (Sparus aurata)
Source Yeast
Validations
Cat. No. ABIN1670041
Quantity 1 mg
Datasheet Datasheet
Reactivity Bullfrog
Source Yeast
Validations
Cat. No. ABIN1665074
Quantity 1 mg
Datasheet Datasheet
Reactivity Xenopus laevis
Source Yeast
Validations
Cat. No. ABIN1664819
Quantity 1 mg
Datasheet Datasheet

Aliases for DIO3 Proteins

iodothyronine deiodinase 3 (DIO3) Proteins
deiodinase, iodothyronine, type 3 (dio3) Proteins
deiodinase, iodothyronine, type III (dio3) Proteins
deiodinase, iodothyronine type III (Dio3) Proteins
deiodinase, iodothyronine, type 3 L homeolog (dio3.L) Proteins
iodothyronine deiodinase 3 (Dio3) Proteins
5DIII Proteins
D3 Proteins
DIOIII Proteins
dioiii Proteins
itdi3 Proteins
txdi3 Proteins
TXDI3 Proteins
XL-15 Proteins
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