Browse our NOS2 Proteins (NOS2)

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Nitric Oxide Synthase 2, Inducible Proteins (NOS2)
On are 22 Nitric Oxide Synthase 2, Inducible (NOS2) Proteins from 7 different suppliers available. Additionally we are shipping NOS2 Antibodies (328) and NOS2 Kits (79) and many more products for this protein. A total of 441 NOS2 products are currently listed.
BmNOS2, HEP-NOS, i-NOS, INO1, iNos, IPS, IPS-1, IPS 1, NOS, Nos-2, NOS-II, NOS2, NOS2a, Nsl
list all proteins Gene Name GeneID UniProt
NOS2 4843 P35228
NOS2 18126 P29477
NOS2 24599 Q06518

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NOS2 Proteins (NOS2) by Origin

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More Proteins for NOS2 Interaction Partners

Rabbit Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. Kidneys from circulation-restricted fetuses showed increased inducible nitric oxide synthase messenger RNA.

  2. The hypotestosteronemia observed in diabetic rabbits could be a consequence of the increased expression of iNOS and could contribute to the hyperreactivity of the rabbit carotid artery to testosterone.

  3. The result demonstrate that mechanical stress on synovial cells induces gene expressions of iNOS.

  4. In heart failure, increased iNOS and arginase II (show ARG2 Proteins) expression results in unchanged NO species and protein S-nitrosylation; with substrate limitation, uncoupled iNOS produces superoxide anions and contributes to contractile dysfunction.

  5. amyloid and oxidative stress-related disease proteins like NOS 2 is increased in expression and form localized accumulations in diabetic muscle in this rabbit model of diabetes.

  6. Pulmonary ischaemia-reperfusion up-regulates inducible nitric oxide synthesis and/activity, which coincides with reduced endothelial nitric oxide synthase (show NOS3 Proteins) activity.

  7. Data suggest distinct localizations of iNOS along the radial arteries and eNOS (show NOS3 Proteins) at the spiral arteries/arterial sinuses in the developing placenta.

  8. Ulinastatin (show AMBP Proteins) effectively inhibited the increased expression of MMP-2 (show MMP2 Proteins), MMP-3 (show MMP3 Proteins), and iNOS in degenerated NP cells induced by IL-1beta (show IL1B Proteins) in vitro.

Pig (Porcine) Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. iNOS was shown to be constitutively expressed within porcine LV. Its level decreases during the progression of systolic nonischemic HF in the pig model.

  2. Our results suggest that the presence of low mycotoxin doses in feed slows down the mRNA expression of both nitric oxide synthase isomers, which probably lowers the concentrations of nitric oxide, a common precursor of inflammation.

  3. In swine, IL-8 (show IL8 Proteins), TNF-ALPHA (show TNF Proteins), INOS AND MIP-1BETA (show CCL4 Proteins) were increased during mechanical ventilation in a time-related fashion.

  4. Data suggest that pig sperm contain bNOS (show NOS1 Proteins), iNOS, and eNOS (show NOS3 Proteins); up-regulation of NOS by leptin (show LEP Proteins) during acrosome reaction and inhibition of acrosome reaction by inhibitors of nitric oxide synthases suggests these enzymes are involved in acrosome reaction.

  5. Periodic acceleration (pGz) acutely increases endothelial and neuronal nitric oxide synthase (show NOS1 Proteins) expression in endomyocardium of normal swine.

  6. Regional difference in blood flow has no effect on iNOS protein content in different size conduit arteries.

  7. Along with several single loci, the epistatic QTLs, SLC9A3R1 and NOS2 control for total number of piglets born and number of piglets born alive in a F(2) Iberian by Meishan intercross.

  8. expression of inducible nitric-oxide synthase by infected mucosa was without detriment to overall barrier function and may serve to promote clearance of infected enterocytes

  9. In this study, neuronal iNOS expression and increase of NO production were found in the acute phase of hypoxia-ischemia. Brain biopterin did not increase in hypoxia-ischemia although plasma biopterin was five-fold elevated.

  10. Immunoreactivity of eNOS (show NOS3 Proteins) was similar to NADPH-d (show NQO1 Proteins) staining. Clear iNOS immunoreactivity was detected in the luminal epithelium, endometrial stroma and individual endometrial glands.

Human Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. The risk of developing chronic pancreatitis is not increased by the presence of the iNOS-2087A>G polymorphism.

  2. NOS2 (show NANOS2 Proteins) rs2779248, NOS2 (show NANOS2 Proteins) rs1137933, and NOS3 (show NANOS3 Proteins) rs3918188 genetic polymorphisms are potentially related to the susceptibility to type 2 diabetes mellitus (T2DM), and the rs1800783 polymorphism might be considered as genetic risk factors for diabetic nephropathy.

  3. Patients wi (show NANOS2 Proteins)th Marfan syndrome showed elev (show ADAMTS1 Proteins)ated NOS2 and decreased ADAMTS1 protein levels in the aorta.

  4. the model demonstrated that although TNF-alpha (show TNF Proteins) contributed towards a more rapid response time, measured as time to reach maximum iNOS production, IFN-gamma (show IFNG Proteins) stimulation was significantly more significant in terms of the maximum expression of iNOS and the concentration of NO produced.

  5. iNOS-derived NO plays a crucial role during atherosclerosis by regulating the endocytic-lysosomal degradation of ILK (show ILK Proteins) in endothelial cells.

  6. analysis of inhibition interaction between AR and iNOS, suggesting a new pathophysiological mechanism and providing a new insight into the therapeutic mechanism of diabetic cataract

  7. During cell transdifferentiation, innate immune activation increases iNOS generation of nitric oxide to S-nitrosylate RING1A.

  8. These results were associated with a long-term improvement in function, which suggests, in light of the current work, that an acute and temporally restricted inhibition of iNOS is needed for the provision of therapeutic benefit.

  9. iNOS showed significantly higher expression with increasing tumour grade in malignant mucinous tumours

  10. high percentages of HIF-1alpha (show HIF1A Proteins) (100%), VEGF (show VEGFA Proteins) (89.5%), iNOS (78.9%), and ET-1 (show EDN1 Proteins) (84.2%) expressions were observed in congenital heart disease autopsy cases and this was found to be significant.

Mouse (Murine) Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. this study shows that knockout of Nos2 in mice lacking Arginase1 ameliorates allergic contact hypersensitivity

  2. Aortic Nos2 levels were higher in Adamts1 (show ADAMTS1 Proteins)-deficient mice and in a mouse model of Marfan syndrome.

  3. iNOS plays a critical role in burn-induced Sirt1 (show SIRT1 Proteins) S-nitrosylation and acetylation and activation of p65 NF-kappaB (show NFkBP65 Proteins) and p53 (show TP53 Proteins) in mouse skeletal muscle.

  4. iNOS-derived NO plays a crucial role during atherosclerosis by regulating the endocytic-lysosomal degradation of ILK (show ILK Proteins) in endothelial cells.

  5. gammadelta T cells express NOS2 not only in vitro after t-cell receptor triggering, but also directly ex vivo. Nos2 deficient mice have fewer gammadelta T cells in peripheral lymph nodes than their wild-type counterparts, and these cells exhibit a reduced ability to produce IL-2. the inactivation of endogenous NOS2 significantly reduced gammadelta T cell proliferation and glycolysis metabolism that can be restored in ...

  6. Stat3 (show STAT3 Proteins) plays a compensatory anti-apoptotic role in IL-17A (show IL17A Proteins)/iNOS-mediated cardiomyocyte apoptosis via inhibiting iNOS transcription, providing a novel molecular mechanism of apoptosis regulation and complicated interactions between IL-17A (show IL17A Proteins)/iNOS and IL-17A (show IL17A Proteins)/Stat3 (show STAT3 Proteins) signalings.

  7. this study shows that iNOS-derived oxidative stress plays a key role in psoriasis induced kidney dysfunction

  8. stability of LPS (show TLR4 Proteins)-induced iNOS mRNA was increased by GlcN under normal glucose conditions. These results suggest that GlcN regulates inflammation by sensing energy states of normal and fuel excess.

  9. this study shows that all-trans retinoic acid enhancement of neutrophil differentiation is iNOS-dependent

  10. H2S recruits iNOS to generate NO to inhibit high glucose-induced NOX4 (show NOX4 Proteins) expression, oxidative stress, and matrix protein accumulation in renal epithelial cells; the two gasotransmitters H2S and NO and their interaction may serve as therapeutic targets in diabetic kidney disease.

Cow (Bovine) Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. polymorphism of the NOS2 gene may contribute to the susceptibility of Holstein cattle to bovine tuberculosis

  2. Vitamin D receptor (show VDR Proteins) activation, and inducible nitric oxide synthase (NOS2), were strongly induced during Cooperia oncophora reinfection. Several canonical pathways associated with NOS2 were impacted.

  3. The expression, localization, and distribution of 3 nitric oxide synthase enzymes through the estrous cycle in bovien fallopian tubes are reported.

  4. These results provide evidence for a high prevalence of subclinical endometritis in repeat breeding cows as well as the involvement of TNFalpha (show TNF Proteins) and iNOS pathways in the regulation of this pathological condition.

  5. Differential cell-specific and spatiotemporal expression of the EDN1 system and NOS in the bovine utero-placental unit may be associated with regulation of vascular and cellular functions during pregnancy.

  6. All infected calves had an increased number of cells expressing iNOS, nitrotyrosine and manganese superoxide dismutase (show SOD2 Proteins) in the inflamed lung tissue

  7. iNOS is expressed in ruminant granulosa cells and is regulated by gonadotrophins and oestradiol

  8. Expression level of NOS2 mRNA in endometrial biopsies from cows with puerperal endometritis is high. Highest expression of is found in cows with clinical endometritis.

  9. data suggest that the transcriptional inducible NOS response to octacalcium phosphate crystals involved both the p38 and the JNK MAPK pathways, probably under the control of activator protein-1

  10. The expression of iNOS and NRAMP1 (show SLC11A1 Proteins) in the lymph nodes, lungs, and tuberculous granulomas in 8 bovine tuberculosis cases is reported.

Guinea Pig Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. The expression of iNOS participates in the pathogenesis of cochlear damage caused by acoustic trauma.

  2. Our data demonstrate that both iNOS and nNOS (show NOS1 Proteins) represent sources for nitric oxide overproduction in ileal myenteric plexus during ischemia and reperfusion

  3. Salvia miltiorrhiza injection had no effect on the expression of nNOS (show NOS1 Proteins) and eNOS (show NOS3 Proteins), but could inhibit iNOS in choclea.

  4. iNOS and AChE expression increases in spiral ganglia treated with streptomycin. Salvia miltiorrhiza injection reduces ototoxicity by reducing the levels of iNOS and AChE.

  5. The auditory brainstem response threshold increases and the expression of iNOS strengthens in streptomycin ototoxicity.

Goat Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. We demonstrated that NOS family genes are expressed in caprine peripheral blood mononuclear cells and higher expression of these genes with HSPs during thermal stress suggest possible involvement of them to ameliorate deleterious effect of thermal stress so as to maintain cellular integrity and homeostasis in goats

NOS2 Protein Profile

Protein Summary

This gene encodes an inositol-3-phosphate synthase enzyme. The encoded protein plays a critical role in the myo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol 1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 4.

Alternative names and synonyms associated with NOS2

  • nitric oxide synthase 2, inducible (NOS2)
  • inositol-3-phosphate synthase 1 (ISYNA1)
  • nitric oxide synthase 2, inducible (Nos2)
  • inducible nitric oxide synthase (nos2)
  • inducible nitric oxide synthase (INOS)
  • inducible nitric oxide synthase (LOC100008833)
  • inducible nitric-oxide synthase (LOC396821)
  • nitric oxide synthase 2 (NOS2)
  • BmNOS2 protein
  • HEP-NOS protein
  • i-NOS protein
  • INO1 protein
  • iNos protein
  • IPS protein
  • IPS-1 protein
  • IPS 1 protein
  • NOS protein
  • Nos-2 protein
  • NOS-II protein
  • NOS2 protein
  • NOS2a protein
  • Nsl protein

Protein level used designations for NOS2

NOS type II , NOS, type II , hepatocyte NOS , inducible NO synthase , inducible NOS , nitric oxide synthase 2A (inducible, hepatocytes) , nitric oxide synthase, inducible , nitric oxide synthase, macrophage , peptidyl-cysteine S-nitrosylase NOS2 , MI-1-P synthase , MIP synthase , myo-inositol 1-phosphate synthase A1 , MAC-NOS , inducible nitric oxide synthase , macrophage NOS , nitric oxide synthase 2, inducible, macrophage , Nitric oxide synthase, inducible , iNOS , NOSII , nitric oxide synthase 2, inducible , nitric oxide synthase 2A , nitric oxide synthase-like protein , nitric-oxide synthase like protein

4843 Homo sapiens
51477 Homo sapiens
18126 Mus musculus
24599 Rattus norvegicus
403822 Canis lupus familiaris
100009437 Oryctolagus cuniculus
100135576 Cavia porcellus
100136036 Oncorhynchus mykiss
282876 Bos taurus
395807 Gallus gallus
396859 Sus scrofa
443078 Ovis aries
455026 Pan troglodytes
706921 Macaca mulatta
791246 Equus caballus
100008833 Oryctolagus cuniculus
396821 Sus scrofa
100860742 Capra hircus
100144542 Bombyx mori
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