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Browse our NOS2 Proteins (NOS2)

Full name:
Nitric Oxide Synthase 2, Inducible Proteins (NOS2)
On www.antibodies-online.com are 21 Nitric Oxide Synthase 2, Inducible (NOS2) Proteins from 7 different suppliers available. Additionally we are shipping NOS2 Antibodies (308) and NOS2 Kits (64) and many more products for this protein. A total of 403 NOS2 products are currently listed.
Synonyms:
HEP-NOS, i-NOS, INO1, iNos, IPS, IPS-1, IPS 1, NOS, Nos-2, NOS-II, NOS2, NOS2a
list all proteins Gene Name GeneID UniProt
NOS2 51477 Q9NPH2
NOS2 18126 P29477
NOS2 24599 Q06518

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More Proteins for NOS2 Interaction Partners

Rabbit Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. The hypotestosteronemia observed in diabetic rabbits could be a consequence of the increased expression of iNOS and could contribute to the hyperreactivity of the rabbit carotid artery to testosterone.

  2. The result demonstrate that mechanical stress on synovial cells induces gene expressions of iNOS.

  3. In heart failure, increased iNOS and arginase II (show ARG2 Proteins) expression results in unchanged NO species and protein S-nitrosylation; with substrate limitation, uncoupled iNOS produces superoxide anions and contributes to contractile dysfunction.

  4. amyloid and oxidative stress-related disease proteins like NOS 2 is increased in expression and form localized accumulations in diabetic muscle in this rabbit model of diabetes.

  5. Pulmonary ischaemia-reperfusion up-regulates inducible nitric oxide synthesis and/activity, which coincides with reduced endothelial nitric oxide synthase (show NOS3 Proteins) activity.

  6. Data suggest distinct localizations of iNOS along the radial arteries and eNOS (show NOS3 Proteins) at the spiral arteries/arterial sinuses in the developing placenta.

  7. Ulinastatin (show AMBP Proteins) effectively inhibited the increased expression of MMP-2 (show MMP2 Proteins), MMP-3 (show MMP3 Proteins), and iNOS in degenerated NP cells induced by IL-1beta (show IL1B Proteins) in vitro.

Pig (Porcine) Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. iNOS was shown to be constitutively expressed within porcine LV. Its level decreases during the progression of systolic nonischemic HF in the pig model.

  2. Our results suggest that the presence of low mycotoxin doses in feed slows down the mRNA expression of both nitric oxide synthase isomers, which probably lowers the concentrations of nitric oxide, a common precursor of inflammation.

  3. In swine, IL-8 (show IL8 Proteins), TNF-ALPHA (show TNF Proteins), INOS AND MIP-1BETA (show CCL4 Proteins) were increased during mechanical ventilation in a time-related fashion.

  4. Data suggest that pig sperm contain bNOS (show NOS1 Proteins), iNOS, and eNOS (show NOS3 Proteins); up-regulation of NOS by leptin (show LEP Proteins) during acrosome reaction and inhibition of acrosome reaction by inhibitors of nitric oxide synthases suggests these enzymes are involved in acrosome reaction.

  5. Periodic acceleration (pGz) acutely increases endothelial and neuronal nitric oxide synthase (show NOS1 Proteins) expression in endomyocardium of normal swine.

  6. Regional difference in blood flow has no effect on iNOS protein content in different size conduit arteries.

  7. Along with several single loci, the epistatic QTLs, SLC9A3R1 and NOS2 control for total number of piglets born and number of piglets born alive in a F(2) Iberian by Meishan intercross.

  8. expression of inducible nitric-oxide synthase by infected mucosa was without detriment to overall barrier function and may serve to promote clearance of infected enterocytes

  9. In this study, neuronal iNOS expression and increase of NO production were found in the acute phase of hypoxia-ischemia. Brain biopterin did not increase in hypoxia-ischemia although plasma biopterin was five-fold elevated.

  10. Immunoreactivity of eNOS (show NOS3 Proteins) was similar to NADPH-d (show NQO1 Proteins) staining. Clear iNOS immunoreactivity was detected in the luminal epithelium, endometrial stroma and individual endometrial glands.

Human Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. Cryptotanshinone and wogonin up-regulate eNOS (show NOS3 Proteins) in vascular endothelial cells via ERalpha (show ESR1 Proteins) and down-regulate iNOS in LPS (show IRF6 Proteins) stimulated vascular smooth muscle cells via ERbeta (show ESR2 Proteins).

  2. NOS2 (show NANOS2 Proteins) is associated with Ezh2 (show EZH2 Proteins)-mediated histone H3 (show HIST3H3 Proteins) lysine 27 methylation in HUVECs

  3. The +2087G allele of the NOS2A gene tended to be significantly associated with periodontal disease. Patients carrying the genotype +2087GG in the NOS2A gene were genetically protected against the development of chronic periodontitis (p = 0.05; OR = 0.44; 95%CI = 0.20-0.95).

  4. PDLIM2 is epigenetically repressed in ovarian cancer development and inhibition of PDLIM2 promoted ovarian cancer growth both in vivo and in vitro via NOS2-derived nitric oxide signaling, leading to recruitment of M2 type macrophages.

  5. In human ovarian cancer cells the inducible nitric oxide synthase (iNOS) is overexpressed leading to increased formation of nitric oxide (NO). The NO promotes a glycolytic phenotype (Warburg effect) leading to H+ generation, which are removed via the sodium, proton (H+) exchanger isoform 1 (NHE1 (show SLC9A1 Proteins)) reducing the intracellular content of this acid equivalent.

  6. i-NOS immunoexpression was not useful in differentiating reactional from non-reactional leprosy

  7. data indicate that up-regulation of twist is correlated with the ER presenting breast cancer, and iNOS expression was positively correlated with tumour-node metastasis (TNM (show ODZ1 Proteins)) staging of breast cancer

  8. INOS and eNOS are the main contributors to NOS-dependent sweating.

  9. This study explores INOS domain interactions by molecular dynamics.

  10. The pathological tissues of Xuanwei lung-cancer patients express high level of NF-kappaB (show NFKB1 Proteins)-p65 (show GORASP1 Proteins), and iNOS.

Mouse (Murine) Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. inhibition of inflammation increases lymphatic vessel density, decreases perilymphatic iNOS expression, increases lymphatic vessel pumping frequency, and restores lymphatic clearance of interstitial fluid to normal levels.

  2. The higher iNOS inhibition activity of the tested Schiff bases, relative to that of COX-2, seems to be a reflection of the combined suppressive effects exerted by their nalidixic acid, isatins (4a-c), and l-amino acid moieties against iNOS expression.

  3. elevated gene expression in allergic mice is downregulated with anti-interleukin 33 (show IL33 Proteins) antibodies

  4. NOS2, while critical to the development of the acute inflammatory response to injury, is also necessary to control the late phase response to bleomycin.

  5. IFNgamma-dependent expression of NOS2 in the brain contributes to BBB breakdown and early mortality in murine PM.

  6. these results suggest that IL-17 (show IL17A Proteins) intensified IFN-gamma-induced (show SAMHD1 Proteins) NOS2 upregulation and NO production by increasing the transcription activity of p-STAT1 (show STAT1 Proteins)(Y701) and NF-kappaB (show NFKB1 Proteins) in RAW 264.7 cells.

  7. 14. These findings indicated that an upregulation of nNOS (show NOS1 Proteins) and iNOS in the spinal cord is associated with bone cancer pain and suggests that exogenously administered L-NMMA may have beneficial effects to alleviate bone cancer pain.

  8. The role of NO and/or iNOS in rabies infection in mice and its effects on other immune molecules

  9. Inhibition of iNOS expression enhanced the therapeutic efficacy of alpha-galactosylceramide by increasing tumor antigen-specific immune response and the suppression of MDSCs.

  10. Amomum tsao-ko fruit extract suppresses lipopolysaccharide-induced inducible nitric oxide synthase by inducing heme oxygenase-1 (show HMOX1 Proteins) in macrophages and in septic mice.

Cow (Bovine) Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. polymorphism of the NOS2 gene may contribute to the susceptibility of Holstein cattle to bovine tuberculosis

  2. Vitamin D receptor (show VDR Proteins) activation, and inducible nitric oxide synthase (NOS2), were strongly induced during Cooperia oncophora reinfection. Several canonical pathways associated with NOS2 were impacted.

  3. The expression, localization, and distribution of 3 nitric oxide synthase enzymes through the estrous cycle in bovien fallopian tubes are reported.

  4. These results provide evidence for a high prevalence of subclinical endometritis in repeat breeding cows as well as the involvement of TNFalpha (show TNF Proteins) and iNOS pathways in the regulation of this pathological condition.

  5. Differential cell-specific and spatiotemporal expression of the EDN1 system and NOS in the bovine utero-placental unit may be associated with regulation of vascular and cellular functions during pregnancy.

  6. All infected calves had an increased number of cells expressing iNOS, nitrotyrosine and manganese superoxide dismutase (show SOD2 Proteins) in the inflamed lung tissue

  7. iNOS is expressed in ruminant granulosa cells and is regulated by gonadotrophins and oestradiol

  8. Expression level of NOS2 mRNA in endometrial biopsies from cows with puerperal endometritis is high. Highest expression of is found in cows with clinical endometritis.

  9. data suggest that the transcriptional inducible NOS response to octacalcium phosphate crystals involved both the p38 and the JNK MAPK pathways, probably under the control of activator protein-1

  10. The expression of iNOS and NRAMP1 (show SLC11A1 Proteins) in the lymph nodes, lungs, and tuberculous granulomas in 8 bovine tuberculosis cases is reported.

Guinea Pig Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. The expression of iNOS participates in the pathogenesis of cochlear damage caused by acoustic trauma.

  2. Our data demonstrate that both iNOS and nNOS (show NOS1 Proteins) represent sources for nitric oxide overproduction in ileal myenteric plexus during ischemia and reperfusion

  3. Salvia miltiorrhiza injection had no effect on the expression of nNOS (show NOS1 Proteins) and eNOS (show NOS3 Proteins), but could inhibit iNOS in choclea.

  4. iNOS and AChE expression increases in spiral ganglia treated with streptomycin. Salvia miltiorrhiza injection reduces ototoxicity by reducing the levels of iNOS and AChE.

  5. The auditory brainstem response threshold increases and the expression of iNOS strengthens in streptomycin ototoxicity.

NOS2 Protein Profile

Protein Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.

Alternative names and synonyms associated with NOS2

  • nitric oxide synthase 2, inducible (NOS2)
  • inducible nitric oxide synthase (INOS)
  • inducible nitric oxide synthase (LOC100008833)
  • inducible nitric oxide synthase (nos2)
  • inducible nitric-oxide synthase (LOC396821)
  • inositol-3-phosphate synthase 1 (ISYNA1)
  • nitric oxide synthase 2, inducible (Nos2)
  • HEP-NOS protein
  • i-NOS protein
  • INO1 protein
  • iNos protein
  • IPS protein
  • IPS-1 protein
  • IPS 1 protein
  • NOS protein
  • Nos-2 protein
  • NOS-II protein
  • NOS2 protein
  • NOS2a protein

Protein level used designations for NOS2

nitric oxide synthase 2A (inducible, hepatocytes) , inducible nitric oxide synthase , NOS type II , inducible NO synthase , inducible NOS , nitric oxide synthase, inducible , peptidyl-cysteine S-nitrosylase NOS2 , MI-1-P synthase , MIP synthase , myo-inositol 1-phosphate synthase A1 , NOS, type II , hepatocyte NOS , nitric oxide synthase, macrophage , MAC-NOS , macrophage NOS , nitric oxide synthase 2, inducible, macrophage , Nitric oxide synthase, inducible , NOSII , iNOS , nitric oxide synthase 2, inducible , nitric oxide synthase 2A

GENE ID SPECIES
455026 Pan troglodytes
791246 Equus caballus
100008833 Oryctolagus cuniculus
100136036 Oncorhynchus mykiss
396821 Sus scrofa
51477 Homo sapiens
4843 Homo sapiens
18126 Mus musculus
24599 Rattus norvegicus
403822 Canis lupus familiaris
100009437 Oryctolagus cuniculus
282876 Bos taurus
395807 Gallus gallus
100135576 Cavia porcellus
100860742 Capra hircus
443078 Ovis aries
396859 Sus scrofa
706921 Macaca mulatta
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