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Browse our NOS2 Proteins (NOS2)

Full name:
Nitric Oxide Synthase 2, Inducible Proteins (NOS2)
On are 21 Nitric Oxide Synthase 2, Inducible (NOS2) Proteins from 7 different suppliers available. Additionally we are shipping NOS2 Antibodies (292) and NOS2 Kits (66) and many more products for this protein. A total of 389 NOS2 products are currently listed.
HEP-NOS, i-NOS, INO1, iNos, IPS, IPS-1, IPS 1, NOS, Nos-2, NOS-II, NOS2, NOS2a
list all proteins Gene Name GeneID UniProt
NOS2 51477 Q9NPH2
NOS2 18126 P29477
NOS2 24599 Q06518

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Rabbit Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. Ulinastatin (show AMBP Proteins) effectively inhibited the increased expression of MMP-2 (show MMP2 Proteins), MMP-3 (show MMP3 Proteins), and iNOS in degenerated NP cells induced by IL-1beta (show IL1B Proteins) in vitro.

  2. Data suggest distinct localizations of iNOS along the radial arteries and eNOS (show NOS3 Proteins) at the spiral arteries/arterial sinuses in the developing placenta.

  3. Pulmonary ischaemia-reperfusion up-regulates inducible nitric oxide synthesis and/activity, which coincides with reduced endothelial nitric oxide synthase (show NOS3 Proteins) activity.

  4. amyloid and oxidative stress-related disease proteins like NOS 2 is increased in expression and form localized accumulations in diabetic muscle in this rabbit model of diabetes.

  5. The result demonstrate that mechanical stress on synovial cells induces gene expressions of iNOS.

  6. In heart failure, increased iNOS and arginase II (show ARG2 Proteins) expression results in unchanged NO species and protein S-nitrosylation; with substrate limitation, uncoupled iNOS produces superoxide anions and contributes to contractile dysfunction.

  7. The hypotestosteronemia observed in diabetic rabbits could be a consequence of the increased expression of iNOS and could contribute to the hyperreactivity of the rabbit carotid artery to testosterone.

Pig (Porcine) Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. Our results suggest that the presence of low mycotoxin doses in feed slows down the mRNA expression of both nitric oxide synthase isomers, which probably lowers the concentrations of nitric oxide, a common precursor of inflammation.

  2. In swine, IL-8 (show IL8 Proteins), TNF-ALPHA (show TNF Proteins), INOS AND MIP-1BETA (show CCL4 Proteins) were increased during mechanical ventilation in a time-related fashion.

  3. Data suggest that pig sperm contain bNOS (show NOS1 Proteins), iNOS, and eNOS (show NOS3 Proteins); up-regulation of NOS by leptin (show LEP Proteins) during acrosome reaction and inhibition of acrosome reaction by inhibitors of nitric oxide synthases suggests these enzymes are involved in acrosome reaction.

  4. Periodic acceleration (pGz) acutely increases endothelial and neuronal nitric oxide synthase (show NOS1 Proteins) expression in endomyocardium of normal swine.

  5. Regional difference in blood flow has no effect on iNOS protein content in different size conduit arteries.

  6. Along with several single loci, the epistatic QTLs, SLC9A3R1 and NOS2 control for total number of piglets born and number of piglets born alive in a F(2) Iberian by Meishan intercross.

  7. expression of inducible nitric-oxide synthase by infected mucosa was without detriment to overall barrier function and may serve to promote clearance of infected enterocytes

  8. In this study, neuronal iNOS expression and increase of NO production were found in the acute phase of hypoxia-ischemia. Brain biopterin did not increase in hypoxia-ischemia although plasma biopterin was five-fold elevated.

  9. Immunoreactivity of eNOS (show NOS3 Proteins) was similar to NADPH-d (show NQO1 Proteins) staining. Clear iNOS immunoreactivity was detected in the luminal epithelium, endometrial stroma and individual endometrial glands.

  10. The increase in NOS protein seen in both the endothelium and vascular smooth muscle in response to cerebral vasospasm is enhanced by dopamine in a D(2)R-dependent mechanism

Human Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. The role of iNOS during tumor development is very complex, with both promoting and inhibiting actions having been described. (Review)

  2. Outcome after BCG (show SLC11A1 Proteins) treatment for urinary bladder cancer may be influenced by polymorphisms in the NOS2 (show NANOS2 Proteins) and NOS3 (show NANOS3 Proteins) genes.

  3. the polymorphisms in iNOS gene (C150T(Ser (show SIGLEC1 Proteins)(608) Leu) polymorphism and polymorphic (CCTTT)n repeats) had no association with cancer risk for all genetic models.

  4. A significant increase in the expression of the p53 (show TP53 Proteins) was observed when iNOS expression was knocked down. The immunoexpression of iNOS is correlated with tumorigenesis and prognosis of OSCC and may serve as a prognostic marker.

  5. we highlight RNS formation and reactive nitrogen species-mediated modifications and their signaling ramifications as a function primarily of NOS2 activation.

  6. These results indicated that b-arr1 regulated ER stress/PUMA-induced mucosal epithelial apoptosis through suppression of the TNF-a/p65/iNOS signaling pathway activation and that b-arr1 is a potential therapeutic target for Portal hypertensive gastropathy.

  7. Dehydroandrographolide, an iNOS inhibitor, extracted from Andrographis paniculata (Burm.f.) Nees, induces autophagy in human oral cancer cells.

  8. These data suggest that tumour-derived iNOS is an important mediator of tumour growth and vessel maturation, hence a promising target for anti-vascular cancer therapies

  9. coactivator p300 (show EP300 Proteins) mediates cytokine-induced hiNOS transactivation by forming a distant DNA loop between its enhancer and core promoter region

  10. hsa (show CD24 Proteins)-miR (show MLXIP Proteins)-26a-5p is a direct regulator of iNOS expression in human chondrocytes

Mouse (Murine) Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. Amomum tsao-ko fruit extract suppresses lipopolysaccharide-induced inducible nitric oxide synthase by inducing heme oxygenase-1 (show HMOX1 Proteins) in macrophages and in septic mice.

  2. Alcohol induces upregulation of iNOS in the intestine and iNOS signaling is required for muR-212 overexpression.

  3. In mice, Collagen-induced arthritis appears to increase the presence of iNOS in aorta, as well as in heart and in kidney microcirculation.

  4. iNOS activity controls inflammation, angiogenesis, and fibrogenesis in polyether-polyurethane synthetic implants.

  5. The findings demonstrated a substantial role of mitochondrial dysfunction in mediating the downregulation of NKCC2 and ENaCalpha in obstructive kidney disease, possibly via iNOS-derived nitric oxide and BNP.

  6. oxLDL induced iNOS expression inhibits macrophage-derived foam cell migration

  7. COX-2 is necessary to protect against tubular injury and apoptosis after unilateral ureteral obstruction but not necessary to protect against oxidative stress

  8. Glabridin downregulated iNOS mRNA expression and activity in LPS (show TLR4 Proteins)-stimulated macrophage-like cells under chronic glucose stress.

  9. Calmodulin (CaM (show Calm2 Proteins)) is essential but not indispensible for the assembly of iNOS and such CaM (show Calm2 Proteins)-free iNOS may help in elucidating the role of CaM (show Calm2 Proteins) on iNOS catalysis.

  10. novel roles for Ifngamma and Nos2 in regulating Actin, Tubulin (show TUBB Proteins), CD11b (show ITGAM Proteins), motility and morphology during the aggregation response of adherent peritoneal exudate

Cow (Bovine) Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. Vitamin D receptor (show VDR Proteins) activation, and inducible nitric oxide synthase (NOS2), were strongly induced during Cooperia oncophora reinfection. Several canonical pathways associated with NOS2 were impacted.

  2. The expression, localization, and distribution of 3 nitric oxide synthase enzymes through the estrous cycle in bovien fallopian tubes are reported.

  3. These results provide evidence for a high prevalence of subclinical endometritis in repeat breeding cows as well as the involvement of TNFalpha (show TNF Proteins) and iNOS pathways in the regulation of this pathological condition.

  4. Differential cell-specific and spatiotemporal expression of the EDN1 system and NOS in the bovine utero-placental unit may be associated with regulation of vascular and cellular functions during pregnancy.

  5. All infected calves had an increased number of cells expressing iNOS, nitrotyrosine and manganese superoxide dismutase (show SOD2 Proteins) in the inflamed lung tissue

  6. iNOS is expressed in ruminant granulosa cells and is regulated by gonadotrophins and oestradiol

  7. Expression level of NOS2 mRNA in endometrial biopsies from cows with puerperal endometritis is high. Highest expression of is found in cows with clinical endometritis.

  8. data suggest that the transcriptional inducible NOS response to octacalcium phosphate crystals involved both the p38 and the JNK MAPK pathways, probably under the control of activator protein-1

  9. The expression of iNOS and NRAMP1 (show SLC11A1 Proteins) in the lymph nodes, lungs, and tuberculous granulomas in 8 bovine tuberculosis cases is reported.

  10. identified a 3471bp transcript for iNOS, isolated from RNA from alveolar macrophages stimulated with the intracellular pathogen Mycobacterium bovis

Guinea Pig Nitric Oxide Synthase 2, Inducible (NOS2) interaction partners

  1. The expression of iNOS participates in the pathogenesis of cochlear damage caused by acoustic trauma.

  2. Our data demonstrate that both iNOS and nNOS (show NOS1 Proteins) represent sources for nitric oxide overproduction in ileal myenteric plexus during ischemia and reperfusion

  3. Salvia miltiorrhiza injection had no effect on the expression of nNOS (show NOS1 Proteins) and eNOS (show NOS3 Proteins), but could inhibit iNOS in choclea.

  4. iNOS and AChE expression increases in spiral ganglia treated with streptomycin. Salvia miltiorrhiza injection reduces ototoxicity by reducing the levels of iNOS and AChE.

  5. The auditory brainstem response threshold increases and the expression of iNOS strengthens in streptomycin ototoxicity.

NOS2 Protein Profile

Protein Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.

Alternative names and synonyms associated with NOS2

  • nitric oxide synthase 2, inducible (NOS2)
  • inducible nitric oxide synthase (INOS)
  • inducible nitric oxide synthase (LOC100008833)
  • inducible nitric oxide synthase (nos2)
  • inducible nitric-oxide synthase (LOC396821)
  • inositol-3-phosphate synthase 1 (ISYNA1)
  • nitric oxide synthase 2, inducible (Nos2)
  • HEP-NOS protein
  • i-NOS protein
  • INO1 protein
  • iNos protein
  • IPS protein
  • IPS-1 protein
  • IPS 1 protein
  • NOS protein
  • Nos-2 protein
  • NOS-II protein
  • NOS2 protein
  • NOS2a protein

Protein level used designations for NOS2

nitric oxide synthase 2A (inducible, hepatocytes) , inducible nitric oxide synthase , NOS type II , inducible NO synthase , inducible NOS , nitric oxide synthase, inducible , peptidyl-cysteine S-nitrosylase NOS2 , MI-1-P synthase , MIP synthase , myo-inositol 1-phosphate synthase A1 , NOS, type II , hepatocyte NOS , nitric oxide synthase, macrophage , MAC-NOS , macrophage NOS , nitric oxide synthase 2, inducible, macrophage , Nitric oxide synthase, inducible , NOSII , iNOS , nitric oxide synthase 2, inducible , nitric oxide synthase 2A

455026 Pan troglodytes
791246 Equus caballus
100008833 Oryctolagus cuniculus
100136036 Oncorhynchus mykiss
396821 Sus scrofa
51477 Homo sapiens
4843 Homo sapiens
18126 Mus musculus
24599 Rattus norvegicus
403822 Canis lupus familiaris
100009437 Oryctolagus cuniculus
282876 Bos taurus
395807 Gallus gallus
100135576 Cavia porcellus
100860742 Capra hircus
443078 Ovis aries
396859 Sus scrofa
706921 Macaca mulatta
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