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Full name:
Preferentially Expressed Antigen in Melanoma ELISA Kits (PRAME)
On www.antibodies-online.com are 8 Preferentially Expressed Antigen in Melanoma (PRAME) ELISA Kits from 6 different suppliers available. Additionally we are shipping PRAME Antibodies (70) and PRAME Proteins (18) and many more products for this protein. A total of 108 PRAME products are currently listed.
Synonyms:
4930534P07Rik, CT130, MAPE, OIP-4, OIP4, PRAME
list all ELISA KIts Gene Name GeneID UniProt
PRAME 23532 P78395
Mouse PRAME PRAME 75829  
Rat PRAME PRAME 680000  

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PRAME (PRAME) ELISA Kits by Reactivity

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Cow (Bovine) Preferentially Expressed Antigen in Melanoma (PRAME) interaction partners

  1. the expansion of the PRAME family occurred in both autosomes and sex chromosomes

Human Preferentially Expressed Antigen in Melanoma (PRAME) interaction partners

  1. Results support the potential utility of NY-ESO-1, PRAME, and MAGEA4 as targets for immunotherapy and as ancillary prognostic parameters in synovial sarcomas.

  2. PRAME plays a role in preventing the invasion and metastasis of lung adenocarcinoma

  3. PRAME is expressed in many primary and metastatic UMs (show TBX3 ELISA Kits), and about half of the metastatic UMs (show TBX3 ELISA Kits) coexpress PRAME and HLA class I (show MICA ELISA Kits).

  4. PRAME is a downstream factor of SOX17 (show SOX17 ELISA Kits) and LIN28 (show LIN28A ELISA Kits) in regulating pluripotency and suppressing somatic/germ cell differentiation in primordial germ cells, germ cell neoplasia in situ, and seminomas.

  5. In line with its roles in controlling cell growth, RPAME regulates multiple critical cell-growth related genes, including IGF1R (show IGF1R ELISA Kits) oncogene (show RAB1A ELISA Kits). IGF1R (show IGF1R ELISA Kits) up-regulation contributes to increase of cell growth upon the knockdown of PRAME.

  6. This study demonstrates that PRAME functions as a tumor suppressor in breast cancer.

  7. PRAME is an independent prognostic biomarker in Uveal melanoma , which identifies increased metastatic risk in patients with Class 1 or disomy 3 tumors.

  8. Leukemias expressing high levels of PRAME had higher levels of cell death by regulating S100A4 (show S100A4 ELISA Kits)/p53 (show TP53 ELISA Kits) signaling.

  9. Our results suggest that the leukemias expressing high levels of PRAME has favorable prognosis

  10. PRAME expression is considered as a poor prognostic parameter in HL.

PRAME Antigen Profile

Antigen Summary

This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene.

Alternative names and synonyms associated with PRAME

  • preferentially expressed antigen in melanoma (PRAME) Elisa Kit
  • preferentially expressed antigen in melanoma (Prame) Elisa Kit
  • 4930534P07Rik Elisa Kit
  • CT130 Elisa Kit
  • MAPE Elisa Kit
  • OIP-4 Elisa Kit
  • OIP4 Elisa Kit
  • PRAME Elisa Kit

Protein level used designations for PRAME

preferentially expressed antigen in melanoma , Opa-interacting protein OIP4 , cancer/testis antigen 130 , melanoma antigen preferentially expressed in tumors , opa-interacting protein 4 , preferentially expressed antigen of melanoma

GENE ID SPECIES
528601 Bos taurus
23532 Homo sapiens
785023 Bos taurus
75829 Mus musculus
680000 Rattus norvegicus
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