Browse our Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Proteins (NPM1)

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Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Proteins (NPM1)
On are 24 Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) Proteins from 10 different suppliers available. Additionally we are shipping Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Antibodies (373) and Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Kits (15) and many more products for this protein. A total of 428 Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) products are currently listed.
B23, B23NP, CG7917, Crp1, Dmel\\CG7917, dNLP, dNLP-S, NO38, Npm, npm4, p22
list all proteins Gene Name GeneID UniProt
NPM1 4869 P06748
NPM1 25498 P13084
NPM1 18148 Q61937

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Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Proteins (NPM1) by Origin

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Top referenced Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Proteins

  1. Human NPM1 Protein expressed in Escherichia coli (E. coli) - ABIN1098300 : Ovcharenko, Stölzel, Poitz, Fierro, Schaich, Neubauer, Kelnar, Davison, Müller-Tidow, Thiede, Bornhäuser, Ehninger, Brown, Illmer: miR-10a overexpression is associated with NPM1 mutations and MDM4 downregulation in intermediate-risk acute myeloid leukemia. in Experimental hematology 2011 (PubMed)
    Show all 2 references for 1098300

  2. Human NPM1 Protein expressed in Wheat germ - ABIN1312882 : Xu, Fang, Dhar, St Clair, Kasarskis, St Clair: The role of a single-stranded nucleotide loop in transcriptional regulation of the human sod2 gene. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for 1312882

  3. Human NPM1 Protein expressed in Escherichia coli (E. coli) - ABIN2001975 : Chan, Chan, Morris, Xie: Isolation and characterization of the human nucleophosmin/B23 (NPM) gene: identification of the YY1 binding site at the 5' enhancer region. in Nucleic acids research 1997 (PubMed)
    Show all 2 references for 2001975

More Proteins for Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Interaction Partners

Human Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) interaction partners

  1. Data suggest that C11orf98 microprotein, NPM1, and nucleolin (show NCL Proteins) interact and colocalize in the cell nucleolus. (C11orf98 = chromosome 11 open reading frame 98 protein; NPM1 = nucleophosmin 1)

  2. data suggest that NPM1 mutations are a secondary or late event in the pathogenesis of AML (show RUNX1 Proteins) and are preceded by founder mutations in genes that may be associated with recently described preclinical states such as clonal hematopoiesis of indeterminate potential or clonal cytopenias of undetermined significance.

  3. Mutations of NPM1 gene is associated with Acute myeloid leukemia (show BCL11A Proteins).

  4. RQ-PCR of the NPM1 type A mutation was more sensitive and reliable than MFC for determination of minimal residual disease , which might have clinical implications.

  5. The results demonstrated that NPM downregulation markedly reversed the effects of multidrug resistance in in human hepatoma cells. In addition, NPM downregulation reduced P-glycoprotein expression, as well as MDR1 expression.

  6. Only karyotype and mutated NPM1 (NPM1mut) were independent predictors of survival in acute myeloid leukemia (show BCL11A Proteins)

  7. Our study provides a method for systematic characterization of NPM1 oligomer formation changes and for screening inhibitors of NPM1 oligomerization.

  8. Mutation of NPM1 determined by the widely available and inexpensive Immunohistochemical(IHC )agrees closely with results of the standard molecular methods. Thus, technically and financially not well endowed laboratories can provide the prognostically and potentially therapeutically important information on NPM1 mutation using IHC.

  9. In pediatric patients with AML (show RUNX1 Proteins) from Argentina, a favorable prognosis of AML (show RUNX1 Proteins) with genotype NPM1-mutated/FLT3 (show FLT3 Proteins)-ITD-negative was confirmed.

  10. This study investigated the expression level of miR-1 (show FSD1 Proteins), miR (show MLXIP Proteins)-486, and let-7a in 45 CN-AML (show RUNX1 Proteins) patients well characterized for FLT3 (show FLT3 Proteins) and/or NPM1 mutations using real-time quantitative RT-PCR and evaluated the association between candidate miRs expression and clinical features

Cow (Bovine) Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) interaction partners

  1. Results suggest that some polymorphisms in NPM1 are associated with body weight at some ages and may be used as candidates for marker-assisted selection and management in beef cattle breeding programmes.

  2. The NPM1 gene is a candidate gene for growth traits in cattle.

Mouse (Murine) Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) interaction partners

  1. study suggests that although neurons need NPM1 (show GJA1 Proteins) for survival, an increase in its expression beyond physiological levels and its translocation to the cytoplasm leads to death through abortive cell cycle induction.

  2. The levels of B23 expression are directly regulated by EGR1 (show EGR1 Proteins).

  3. IDH2 (show IDH2 Proteins) and NPM1 (show GJA1 Proteins) mutations synergize in the development and maintenance of acute myeloid leukemia (show BCL11A Proteins) stem-like cells.

  4. Lrrc34, a novel nucleolar protein (show MCRS1 Proteins), interacts with npm1 (show GJA1 Proteins) and ncl (show NCL Proteins) and has an impact on pluripotent stem cells

  5. a function of NPM1 (show GJA1 Proteins) in the spatial organization of nucleolus-associated heterochromatin through DNA methyltransferase (show DNMT1 Proteins) DNMT3A (show DNMT3A Proteins)

  6. The data presented here support a novel role for NPM1 (show GJA1 Proteins) as a multilevel modulator of the base excision repair pathway.

  7. The mechanism of G-CSF's neuroprotection may be related in part to attenuating neuronal apoptosis by NPM1 (show GJA1 Proteins).

  8. In conclusion, we successfully established xenotransplantation model of human FLT3 (show FLT3 Proteins)-ITD (mut (show MUT Proteins)) /NPM1 (show GJA1 Proteins) (-) CN-AML (show RUNX1 Proteins) in NOD/SCID (show PRKDC Proteins) mice.

  9. This in vivo model of Flt3 (show FLT3 Proteins)/ITD+/NPMc+ leukemia closely recapitulates human disease and will therefore serve as a tool for the investigation of the biology of this common disease entity

  10. HOPS acts as a functional bridge in the interaction between NPM and p19(Arf)

Fruit Fly (Drosophila melanogaster) Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) interaction partners

  1. NLP is essential for the positioning of centromeres during cell division in Drosophila.

Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) Protein Profile

Protein Summary

This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1)

  • nucleophosmin-like (LOC100059112)
  • nucleophosmin/nucleoplasmin, 1b (npm1b)
  • Nucleophosmin (npm)
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1)
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin) (npm1)
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin) (Npm1)
  • nucleophosmin 1 (Npm1)
  • nucleophosmin-like (LOC100525313)
  • Nucleoplasmin (Nlp)
  • B23 protein
  • B23NP protein
  • CG7917 protein
  • Crp1 protein
  • Dmel\\CG7917 protein
  • dNLP protein
  • dNLP-S protein
  • NO38 protein
  • Npm protein
  • npm4 protein
  • p22 protein

Protein level used designations for NPM1

nucleophosmin , nucleophosmin/nucleoplasmin, 4 , Nucleophosmin , nucleolar protein NO38 , nucleophosmin/nucleoplasmin family, member 1 , NPM , nucleolar phosphoprotein B23 , nucleoplasmin , numatrin , nucleolar protein B23.1 , nucleophosmin 1 , CG7917-PA , CG7917-PB , Nlp-PA , Nlp-PB , Nucleoplasmin-like , chromatin decondensation protein 1 , nucleoplasmin-1

100059112 Equus caballus
553507 Danio rerio
100195119 Salmo salar
4869 Homo sapiens
379194 Xenopus laevis
396203 Gallus gallus
25498 Rattus norvegicus
479292 Canis lupus familiaris
614028 Bos taurus
100328693 Oryctolagus cuniculus
740704 Pan troglodytes
18148 Mus musculus
100525313 Sus scrofa
43560 Drosophila melanogaster
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