Browse our Methionine Adenosyltransferase II, alpha Proteins (MAT2A)

On are 16 Methionine Adenosyltransferase II, alpha (MAT2A) Proteins from 9 different suppliers available. Additionally we are shipping Methionine Adenosyltransferase II, alpha Antibodies (90) and Methionine Adenosyltransferase II, alpha Kits (17) and many more products for this protein. A total of 127 Methionine Adenosyltransferase II, alpha products are currently listed.
D630045P18Rik, fd12a12, m(2)21ab, mat2a, MATA2, MATII, MGC76253, MGC79598, Sams2, si:ch73-340n8.1, wu:fb95e01, wu:fd12a12
list all proteins Gene Name GeneID UniProt
MAT2A 4144 P31153
MAT2A 232087 Q3THS6
MAT2A 171347 P18298

Methionine Adenosyltransferase II, alpha Proteins (MAT2A) by Origin

More Proteins for Methionine Adenosyltransferase II, alpha Interaction Partners

Human Methionine Adenosyltransferase II, alpha (MAT2A) interaction partners

  1. METTL16 (show METTL16 Proteins) that controls MAT2A intron retention in response to intracellular SAM (show TTN Proteins) levels; splicing of the MAT2A retained intron is rapidly induced upon Met depletion, and this effect requires a conserved hairpin which is a METTL16 (show METTL16 Proteins) m6A (show GPM6A Proteins) substrate.

  2. S-adenosyl-L-methionine (show AS3MT Proteins) diminishes hepatitis C virus expression by altering MAT1A (show MAT1A Proteins)/2A signaling in hepatocytes.

  3. methionine adenosyltransferase II alpha (MAT2A), and the arginine methyltransferase, PRMT5 (show PRMT5 Proteins), as vulnerable enzymes in cells with MTAP (show MTAP Proteins) deletion.

  4. acet (show EP300 Proteins)ylation decreased in hepatocellular cancer

  5. The data presented here support the conclusion that rare genetic variants in MAT2A predispose individuals to thoracic aortic disease.

  6. Results suggest that MAT2A is downregulated in cancer tissues of renal cell carcinomas patients and has function of tumor suppressor though repressing the expression of heme oxygenase-1 (show HMOX1 Proteins).

  7. Liver-specific isoenzyme MAT1A (show MAT1A Proteins) is genetically linked with an inborn metabolic disorder of hypermethioninemia, as well as a ubiquitously expressed isoenzyme MAT2A, whose enzymatic activity is regulated by an associated subunit MAT2B (show MAT2B Proteins).

  8. Differential gene expression of BACE1 (show BACE Proteins) and PSEN1 (show PSEN1 Proteins) in the knockdown cells, which is possibly a consequence of MAT2A deregulation and may indicate a self regulatory mechanism.

  9. we found for the first time a post-transcriptional regulation of MAT1A (show MAT1A Proteins) and MAT2A by AUF1 (show HNRNPD Proteins) and HuR (show ELAVL1 Proteins) in hepatocellular carcinoma.

  10. hypoxia-induced MAT2A expression is HIF-1alpha (show HIF1A Proteins) dependent

Mouse (Murine) Methionine Adenosyltransferase II, alpha (MAT2A) interaction partners

  1. P300 (show NOTCH1 Proteins) acetylates MAT IIalpha at lysine residue 81 and destabilizes MAT IIalpha by promoting its ubiquitylation and subsequent proteasomal degradation.

  2. MATIIalpha represses the expression of cyclooxygenase 2 (COX-2 (show PTGS2 Proteins)), encoded by Ptgs2 (show PTGS2 Proteins), by specifically interacting with histone H3K9 methyltransferase SETDB1 (show SETDB1 Proteins).

  3. Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf (show MAF Proteins) oncoprotein

  4. MAT2A and MAT2beta (show MAT2B Proteins) genes are induced during hepatic stellate cell activation

  5. up-regulation of MAT2A also provides a growth advantage and s-adenosylmethionine and methylthioadenosine can block mitogenic signaling in colon cancer cells.

Methionine Adenosyltransferase II, alpha (MAT2A) Protein Profile

Protein Summary

The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes.

Alternative names and synonyms associated with Methionine Adenosyltransferase II, alpha (MAT2A)

  • methionine adenosyltransferase II, alpha (mat2a)
  • methionine adenosyltransferase II, alpha (MAT2A)
  • methionine adenosyltransferase II, alpha (Mat2a)
  • methionine adenosyltransferase II, alpha a (mat2aa)
  • D630045P18Rik protein
  • fd12a12 protein
  • m(2)21ab protein
  • mat2a protein
  • MATA2 protein
  • MATII protein
  • MGC76253 protein
  • MGC79598 protein
  • Sams2 protein
  • si:ch73-340n8.1 protein
  • wu:fb95e01 protein
  • wu:fd12a12 protein

Protein level used designations for MAT2A

methionine adenosyltransferase II, alpha , S-adenosylmethionine synthetase isoform type-2-like , MAT 2 , MAT-II , S-adenosylmethionine synthase isoform type-2 , adoMet synthase 2 , adoMet synthetase 2 , methionine adenosyltransferase 2 , S-adenosylmethionine synthetase isoform type-2 , non-hepatic-type S-adenosylmethionine synthetase

379867 Xenopus laevis
395032 Xenopus (Silurana) tropicalis
459363 Pan troglodytes
475770 Canis lupus familiaris
695362 Macaca mulatta
100339456 Oryctolagus cuniculus
100412649 Callithrix jacchus
4144 Homo sapiens
100173772 Pongo abelii
232087 Mus musculus
171347 Rattus norvegicus
100312974 Sus scrofa
527403 Bos taurus
323329 Danio rerio
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