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MBD2 Proteins

(Methyl-CpG Binding Domain Protein 2 (MBD2))

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].

recommended

MBD2 Protein (AA 1-411) (Strep Tag) (ABIN3083393)

Crystallography grade MBD2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA

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recommended

MBD2 Protein (AA 1-414) (Strep Tag) (ABIN3120369)

Crystallography grade MBD2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA

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recommended

MBD2 Protein (AA 145-411) (His tag) (ABIN7417450)

MBD2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC

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MBD2 Proteins by Grade

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MBD2 Proteins by Origin

Find MBD2 Proteins for a variety of species such as anti-Human MBD2, anti-Mouse MBD2. The species listed below are among those available. Click on a link to go to the corresponding products.

MBD2 Proteins by Source

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MBD2 Proteins by Protein Type

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MBD2 Proteins by Application

Find MBD2 Proteins validated for a specific application such as SDS, WB, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular MBD2 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

MBD2 Protein (AA 1-411) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3083393

Quantity 1 mg

Datasheet Datasheet

MBD2 Protein (AA 1-414) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3120369

Quantity 1 mg

Datasheet Datasheet

MBD2 Protein (AA 145-411) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7417450

Quantity 100 μg

Datasheet Datasheet

Aliases for MBD2 Proteins

methyl-CpG binding domain protein 2 (MBD2) Proteins
methyl-CpG binding domain protein 2 (Mbd2) Proteins
methyl-CpG binding domain protein 2 (mbd2) Proteins
methyl-CpG binding domain protein 2 S homeolog (mbd2.S) Proteins
DMTase Proteins
MBD2 Proteins
MBD2a Proteins
NY-CO-41 Proteins
wu:fa97f06 Proteins
zgc:111862 Proteins

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MBD2 Proteins by Grade

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Popular MBD2 Proteins

Aliases for MBD2 Proteins

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