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MAT2A Products

(Methionine Adenosyltransferase II, alpha (MAT2A))
The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011].

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Featured MAT2A Categories

MAT2A Antibodies

High quality antibodies with extensive validation data.

MAT2A ELISA Kits

Reliable ELISA kits for a wide range of species.

MAT2A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MAT2A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (3)
Cat. No. ABIN7168530
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (3)
Cat. No. ABIN2782513
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN1912293
Quantity 200 μL
Datasheet Datasheet

Recommended MAT2A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968590
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957792
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957793
Quantity 96 tests
Datasheet Datasheet

Recommended MAT2A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3083670
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3121811
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310438
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our MAT2A products

Stone, El-Brolosy, Wilhelm, Liu, Romão, Grillo, Lai, Günther, Jeratsch, Kuenne, Lee, Braun, Santoro, Locasale, Potente, Stainier: "Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells." in: Nature communications, Vol. 9, Issue 1, pp. 4077, (2019) (PubMed).

Wang, Fang, Liu, Gao, Wang, Zhu, Zhu, Ji, Wu, Ma, Hu, Shen, Gao, Zhu, Liu, Zhou: "TGF-β1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM." in: EBioMedicine, Vol. 42, pp. 458-469, (2019) (PubMed).

Tomasi, Cossu, Spissu, Floris, Ryoo, Iglesias-Ara, Wang, Pandol, Bhowmick, Seki, Posadas, Lu: "S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting microRNA 34a/b-methionine adenosyltransferase 2A/2B axis." in: Oncotarget, Vol. 8, Issue 45, pp. 78851-78869, (2018) (PubMed).

Zhong, Liu, Lin, Hu, Yuan, Liu, Zhou, Xu, Hu, Wang, Guan, Hao, Lui, Guo, Mai, Chen, Han, Xia, Grandis, Zhang, Zeng: "The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 3, pp. 659-673, (2018) (PubMed).

Scotton, Bovolenta, Schwartz, Falzarano, Martoni, Passarelli, Armaroli, Osman, Rodolico, Messina, Pegoraro, DAmico, Bertini, Gualandi, Neri, Selvatici, Boffi, Maioli, Lochmüller, Straub, Bushby et al.: "Deep RNA profiling identified CLOCK and molecular clock genes as pathophysiological signatures in collagen VI myopathy. ..." in: Journal of cell science, Vol. 129, Issue 8, pp. 1671-84, (2016) (PubMed).

Phuong, Kim, Im, Yang, Choi, Lim, Lee, Kim, Yoon, Kang: "Induction of methionine adenosyltransferase 2A in tamoxifen-resistant breast cancer cells." in: Oncotarget, Vol. 7, Issue 12, pp. 13902-16, (2016) (PubMed).

Ramani, Donoyan, Tomasi, Park: "Role of methionine adenosyltransferase α2 and β phosphorylation and stabilization in human hepatic stellate cell trans-differentiation." in: Journal of cellular physiology, Vol. 230, Issue 5, pp. 1075-85, (2015) (PubMed).

Rho, Lampe: "High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays." in: Journal of proteome research, Vol. 12, Issue 5, pp. 2311-20, (2013) (PubMed).

Ramani, Tomasi: "Transcriptional regulation of methionine adenosyltransferase 2A by peroxisome proliferator-activated receptors in rat hepatic stellate cells." in: Hepatology (Baltimore, Md.), Vol. 55, Issue 6, pp. 1942-53, (2012) (PubMed).

Nordgren, Peng, Pelleymounter, Moon, Abo, Feng, Eckloff, Yee, Wieben, Weinshilboum: "Methionine adenosyltransferase 2A/2B and methylation: gene sequence variation and functional genomics." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 39, Issue 11, pp. 2135-47, (2011) (PubMed).

Synonyms and alternative names related to MAT2A

methionine adenosyltransferase 2A (MAT2A), methionine adenosyltransferase 2A (Mat2a), methionine adenosyltransferase II, alpha (Mat2a), methionine adenosyltransferase II, alpha a (mat2aa), methionine adenosyltransferase II, alpha L homeolog (mat2a.L), methionine adenosyltransferase II, alpha (mat2a), methionine adenosyltransferase II, alpha b (mat2ab), D630045P18Rik, fd12a12, m(2)21ab, mat2a, MATA2, MATII, MGC76253, MGC79598, SAMS2, Sams2, si:ch73-340n8.1, wu:fb95e01, wu:fd12a12, zgc:110847

Protein level used designations for MAT2A

  • MAT 2
  • MAT-II
  • S-adenosylmethionine synthase isoform type-2
  • adoMet synthase 2
  • adoMet synthetase 2
  • methionine adenosyltransferase 2
  • S-adenosylmethionine synthetase isoform type-2
  • non-hepatic-type S-adenosylmethionine synthetase
  • methionine adenosyltransferase II, alpha
  • S-adenosylmethionine synthetase isoform type-2-like
  • S-adenosylmethionine synthase
  • S-adenosylmethionine synthetase isoform type 2
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