Browse our Amphiregulin Proteins (AREG)

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Amphiregulin Proteins (AREG)
On are 22 Amphiregulin (AREG) Proteins from 12 different suppliers available. Additionally we are shipping Amphiregulin Kits (95) and Amphiregulin Antibodies (89) and many more products for this protein. A total of 211 Amphiregulin products are currently listed.
list all proteins Gene Name GeneID UniProt
AREG 11839 P31955
AREG 374 P15514
AREG 29183 P24338

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Amphiregulin Proteins (AREG) by Origin

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Top referenced Amphiregulin Proteins

  1. Mouse (Murine) Amphiregulin Protein expressed in Escherichia coli (E. coli) - ABIN2666769 : Plowman, Green, McDonald, Neubauer, Disteche, Todaro, Shoyab: The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity. in Molecular and cellular biology 1990 (PubMed)
    Show all 9 references for 2666769

More Proteins for Amphiregulin Interaction Partners

Mouse (Murine) Amphiregulin (AREG) interaction partners

  1. activated alveolar macrophages also exerted a protective effect on the lung tissues by producing high-level amphiregulin in lipopolysaccharide-induced acute lung injury

  2. AREG overexpression in osteoblasts induces a transient high bone mass phenotype in the trabecular compartment of the appendicular skeleton by a growth-related, non-cell autonomous mechanism

  3. AREG-silenced keratinocytes plays an important role in regulation cell proliferation.

  4. Hepatic CD206 (show MRC1 Proteins)-positive macrophages express amphiregulin to promote the immunosuppressive activity of regulatory T cells in HBV infection.

  5. Areg may have a role in classically activated macrophages

  6. After activation with IL-33 (show IL33 Proteins), expression of AREG is a dominant functional signature of gut (show GUSB Proteins)-associated IL-33 (show IL33 Proteins)-dependent group 2 innate lymphoid cells. The frequency and number of AREG-expressing ILC2s increases following intestinal injury.

  7. AR induces hHSC fibrogenic activity via multiple mitogenic signaling pathways, and is upregulated in murine and human NASH, suggesting that AR antagonists may be clinically useful anti-fibrotics in NAFLD.

  8. hormones and/or factors in addition to E that upregulate AREG can promote mammary gland development and have the potential to affect breast cancer risk associated with pubertal mammary gland development

  9. Our data show that AREG is essential for ultraviolet therapy-induced contact hypersensitivity suppression.

  10. Pre-maturation with cAMP modulators in conjunction with EGF (show EGF Proteins)-like peptides during in vitro maturation enhances mouse oocyte developmental competence.

Pig (Porcine) Amphiregulin (AREG) interaction partners

  1. LH and AREG decrease BNP and CNP (show NPPC Proteins) production in granulosa cells and down-regulate NPR2 (show NPRL2 Proteins) expression in cumulus cells, which together decreased oocyte cGMP to levels that permit meiotic resumption.

  2. cloning the complete coding region; comparison of endometrial amphiregulin mRNA expression in Meishan and White composite pigs

Human Amphiregulin (AREG) interaction partners

  1. AREG expression may be useful for identifying CRTC1-MAML2-positive mucoepidermoid carcinomas and as a marker for favorable prognosis.

  2. Amphiregulin enhances VEGF-A (show VEGFA Proteins) production in human chondrosarcoma cells and promotes angiogenesis by inhibiting miR (show MLXIP Proteins)-206 via FAK (show PTK2 Proteins)/c-Src (show SRC Proteins)/PKCdelta (show PKCd Proteins) pathway.

  3. Amphiregulin plays an important role in lung neoplasm resistance to amrubicinol

  4. EREG (show EREG Proteins) and AREG are strongly regulated by methylation, and their expression is associated with CIMP status and primary tumour site.

  5. These findings demonstrate the posttranslational regulation of Foxp3 (show FOXP3 Proteins) expression by AREG in cancer patients through AREG/EGFR (show EGFR Proteins)/GSK-3beta signaling, which could lead to Foxp3 (show FOXP3 Proteins) protein degradation in Treg cells and a potential therapeutic target for cancer treatment.

  6. blocking soluble amphiregulin with a neutralizing antibody also significantly increased apoptotic cell death of HepG2 cells due to treatment with methyl methanesulfonate, cisplatin, or a recombinant p53 (show TP53 Proteins) adenovirus, suggesting that the function of amphiregulin involved in inhibiting apoptosis may be a common mechanism by which hepatoma cells escape from stimulus-induced apoptosis

  7. Low AREG expression is associated with gastric cancer.

  8. RYR2, PTDSS1 (show PTDSS1 Proteins) and AREG are autism susceptibility genes that are implicated in a Lebanese population-based study of copy number variations in this disease.

  9. High Amphiregulin enhances intercellular adhesion molecule-1 (show ICAM1 Proteins) expression and promotes tumor metastasis in osteosarcoma.

  10. results demonstrate that AREG controls G2/M progression and cytokinesis in keratinocytes via activation of a FoxM1 (show FOXM1 Proteins)-dependent transcriptional program, suggesting new avenues for treatment of epithelial cancer

Cow (Bovine) Amphiregulin (AREG) interaction partners

  1. Amphiregulin co-operates with bone morphogenetic protein 15 (show BMP15 Proteins) to increase bovine oocyte developmental competence.

  2. Data suggest that epidermal growth factor receptor (show EGFR Proteins) B [ErbB (show EGFR Proteins)] isoforms and their ligands (epidermal growth factor (show EGF Proteins) [EGF (show EGF Proteins)], amphiregulin [AREG], and neuregulin-1 (show NRG1 Proteins) [NRG1 (show NRG1 Proteins)]) are expressed in uteroplacental tissues in mid- and late-phases of pregnancy.

Amphiregulin (AREG) Protein Profile

Protein Summary

Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.

Alternative names and synonyms associated with Amphiregulin (AREG)

  • amphiregulin (Areg)
  • amphiregulin (AREG)
  • amphiregulin B (AREGB)
  • amphiregulin preproprotein-like (LOC100354550)
  • amphiregulin-like (LOC538751)
  • amphiregulin-like (LOC100050528)
  • amphiregulin-like (LOC100732447)
  • AR protein
  • AREG protein
  • AREG/SDGF protein
  • AREGB protein
  • CRDGF protein
  • SDGF protein

Protein level used designations for Amphiregulin Proteins (AREG)

schwannoma-derived growth factor , amphiregulin (schwannoma-derived growth factor) , amphiregulin long form , colorectum cell-derived growth factor , AR , SDGF , Schwannoma-derived growth factor , amphiregulin , amphiregulin B

11839 Mus musculus
397668 Sus scrofa
374 Homo sapiens
29183 Rattus norvegicus
443427 Ovis aries
727738 Homo sapiens
428752 Gallus gallus
475176 Canis lupus familiaris
100354550 Oryctolagus cuniculus
538751 Bos taurus
100050528 Equus caballus
100732447 Cavia porcellus
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