Amphiregulin Protein (AREG) (AA 100-248) (hFc Tag)
Quick Overview for Amphiregulin Protein (AREG) (AA 100-248) (hFc Tag) (ABIN7273805)
Target
See all Amphiregulin (AREG) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 100-248
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Purification tag / Conjugate
- This Amphiregulin protein is labelled with hFc Tag.
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Purpose
- Mouse AREG Protein
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Sequence
- Val100-Ala248
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Characteristics
- Recombinant Mouse AREG Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Val100-Ala248.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Mouse AREG on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse AREG is greater than 95% as determined by SEC-HPLC.
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Amphiregulin (AREG) (Active) protein
AREG Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Amphiregulin (AREG) (AA 101-187) (Active) protein (hFc Tag)AREG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Amphiregulin (AREG) (AA 1-252) protein (GST tag)AREG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Amphiregulin (AREG) (AA 101-198) protein (His tag)AREG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Amphiregulin (AREG) (AA 20-187) protein (Fc Tag)AREG Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- Amphiregulin (AREG)
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Alternative Name
- AREG
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Background
- Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor.
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Molecular Weight
- 38.6 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.
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UniProt
- P31955
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Pathways
- RTK Signaling, EGFR Signaling Pathway
Target
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