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Human Angiopoietin 1 Protein expressed in Escherichia coli (E. coli) - ABIN667576
Kopczyńska, Makarewicz, Biedka, Kaczmarczyk, Kardymowicz, Tyrakowski: Plasma concentration of angiopoietin-1, angiopoietin-2 and Tie-2 in cervical cancer. in European journal of gynaecological oncology 2010
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Zebra fish (Danio rerio) morphants showed that mild knock down of Ang-1 produces a small-brained phenotype that could be rescued with Ang-1 mRNA.
COMP (show COMP Proteins)-Ang1 can enhance BMP2 (show BMP2 Proteins)-induced cranial bone regeneration with increased pericyte recruitment. Combined delivery of the proteins might be a therapeutic strategy to repair cranial bone damage.
Hematopoietic stem cells regulate the regeneration of their niche by secreting Angpt1.
Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart.
Ang-1 strongly enhances skeletal muscle regeneration in response to fiber injury and that this effect is mediated through induction of the myogenesis program in muscle progenitor cells and the angiogenesis program in endothelial cells.
These results suggest that PRP extract prevents endotoxin-induced pulmonary edema mainly through Ang (show ANG Proteins)-Tie2 (show TEK Proteins) signaling, and PRP extract could be a potential therapeutic strategy for sepsis-induced pulmonary edema
E2 increases Ang-1 and enhances capillary density in brain under basal conditions through estrogen receptor-alpha (show ESR1 Proteins), priming the middle cerebral artery territory for survival after experimental focal ischemia
The important role of Ang-1 in the activation of mast cells, and a potential therapeutic effect of Ang-1 on anaphylaxis diseases.
findings report that Ang-1 induces arteriolar vasodilation via release of NO, suggesting that Ang-1 is an important regulator of microvascular tone.
Sonic hedgehog secreted by neurons regulates ang-1 and ang-2 expression in neighboring fibroblasts.
The Ang-1, Ang-2 (show ANGPT2 Proteins), Tie-2 (show TEK Proteins) system takes part in the pathologic processes in the brains that suffered acute carbon monoxide poisoning by participating in neovascularization.
Plasma Ang-1 levels were diminished in Behcet's disease patients, especially in patients with vascular involvement.
Ang2 (show ANGPT2 Proteins)/Ang1 ratio might constitute a useful tool for monitoring the progression of chronic liver disease towards cirrhosis and play an important role as therapeutic target.
Data suggest that ANGPT1 is active in tight junctions and adherens junctions in the up-regulation of pathophysiological angiogenesis in ovarian follicles in ovarian hyperstimulation syndrome. Follicular fluid from women at risk of ovarian hyperstimulation syndrome in Argentina was used in these studies.
the results of the present study suggest that aHSCs increased the expression of Ang-1, resulting in angiogenesis in HCC (show FAM126A Proteins) tissues, thus promoting the growth and metastasis of HCC (show FAM126A Proteins).
Results found that MCT (show MCAT Proteins) contributes to endothelial cell growth and tube formation via up-regulation of angiopoietin-1 expression suggesting that MCT (show MCAT Proteins) plays an important role in pancreatic cancer angiogenesis and tumor growth via activating the angiopoietin-1 pathway.
Angiopoietin 1 levels were significantly higher in nasopharyngeal cancer patients.
High Ang 1 expression in hilar cholangiocarcinoma and infiltration of TIE2-expressing monocytes (TEMs) defines a subgroup of patients with beneficial tumor characteristics and prolonged survival. Low Ang 2 levels tended to inversely correlate with TEMs invasion.
GTPCH (show GCH1 Proteins)/Ang-1 interaction in stromal fibroblasts and activation of Tie2 (show TEK Proteins) on breast tumor cells could play an important role in supporting breast cancer growth.
the homeostasis of vascular endothelial function by Ang-1 and Ang-2 (show ANGPT2 Proteins) is disrupted in macrophage activation syndrome (MAS (show MAS1 Proteins)); the Ang-2 (show ANGPT2 Proteins)/1 ratio was significantly elevated in the active phase of s-JIA; serum Ang-1 levels were significantly decreased in MAS (show MAS1 Proteins), whereas the serum Ang-2 (show ANGPT2 Proteins) levels and the Ang-2 (show ANGPT2 Proteins)/1 ratio were significantly elevated in MAS (show MAS1 Proteins)
ANGPT1 may be associated with taxol resistance of nasopharyngeal carcinoma cells.
Angiopoietin 1 was predominantly present in the maturing glomeruli.
The expression of ANGPT1 has already been studied during metanephric glomerulogenesis, but it remains to be elucidated during the development of the embryonic mesonephros.
Attenuates H2O2-induced stress-activated protein kinase (show CDK7 Proteins) (SEK)1 (show MAP2K4 Proteins)/JNK (show MAPK8 Proteins) phosphorylation through the PI 3 (show PI3 Proteins)-kinase/Akt (show AKT1 Proteins) pathway and inhibits the apoptosis of vascular endothelial cells induced by oxidative stress.
Estrogen-dependent control of Ang-1 expression plays an important role in stabilizing meningeal microvessel and maintaining healthy microvascular networks.
Angiopoietin-1 receptor Tie2 (show TEK Proteins) distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells.
inhibition of NO production by Ang-1, via phosphorylation of eNOS (show NOS3 Proteins) on Thr (show TRH Proteins)(497) by PKC zeta (show PRKCZ Proteins), is responsible, at least in part, for inhibition of VEGF (show VEGFA Proteins)-stimulated endothelial permeability by Ang-1.
Involved in the conversion of lanosterol to cholesterol.
, angiopoietin 1
, C-14 sterol reductase
, another new gene 1 protein
, delta(14)-sterol reductase
, putative sterol reductase SR-1
, sterol C14-reductase