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Human FGF10 Protein expressed in Escherichia coli (E. coli) - ABIN2666429
El Agha, Bellusci et al.: Walking along the Fibroblast Growth Factor 10 Route: A Key Pathway to Understand the Control and Regulation of Epithelial and Mesenchymal Cell-Lineage Formation during Lung Development and Repair ... in Scientifica 2014
Show all 7 references for ABIN2666429
Human FGF10 Protein expressed in Escherichia coli (E. coli) - ABIN2667400
Benjamin, Carver, Plosa, Yamamoto, Miller, Liu, van der Meer, Blackwell, Prince: NF-kappaB activation limits airway branching through inhibition of Sp1-mediated fibroblast growth factor-10 expression. in Journal of immunology (Baltimore, Md. : 1950) 2010
Show all 6 references for ABIN2667400
Human FGF10 Protein expressed in Escherichia coli (E. coli) - ABIN668016
Entesarian, Matsson, Klar, Bergendal, Olson, Arakaki, Hayashi, Ohuchi, Falahat, Bolstad, Jonsson, Wahren-Herlenius, Dahl: Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands. in Nature genetics 2005
Show all 2 references for ABIN668016
Human FGF10 Protein expressed in Escherichia coli (E. coli) - ABIN2003082
Gupte, Ramasamy, Reddy, Lee, Weinreb, Violette, Guenther, Warburton, Driscoll, Minoo, Bellusci: Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice. in American journal of respiratory and critical care medicine 2009
Fgf3 (show FGF3 Proteins) and Fgf10a work in concert to promote maturation of the epibranchial placodes in zebrafish.
Fgf10 and Fgf3 (show FGF3 Proteins) secreted from the forming neurohypophysis exert direct guidance effects on hypothalamic neurosecretory axons.
through the analysis of fgf10(-/-); fgf24(-/-) embryos, the specific role of these two FGF ligands in the induction of the ventral pancreas and in the repression of the hepatic fate was revealed.
fgf10a, which is expressed in the mesenchyme surrounding non-hepatic endodermal cells, negatively impacts the regulative capacity of endodermal tissues.
Functional investigation of a subset of these genes, fgf10a, tgfb2 (show TGFB2 Proteins), pax9 (show PAX9 Proteins), and smad5 (show SMAD5 Proteins) revealed their necessity in zebrafish palatogenesis.
Data show that the Ihha-Fgf10 regulatory interaction is realized through a signaling feedback loop between the Ihha-expressing epithelium and Fgf10-expressing mesenchyme.
These data provide in vivo evidence that endodermal cells outside the liver-forming region retain hepatic competence and show that an extrinsic signal, Fgf10a, negatively regulates hepatic competence.
Positional cloning identifies fgf10 as the gene disrupted in daedalus.
Fgf10 signaling from the adjacent mesenchyme is responsible for refining the boundaries
Fgf10 acts redundantly with Fgf24 in the pancreatic lateral plate mesoderm and they are both required to specify the ventral pancreas.
data suggest that the strongest signal of association at 5p12 is mediated through coordinated activation of FGF10 and MRPS30 (show MRPS30 Proteins), two candidate genes for breast cancer pathogenesis
Fgf10 signaling has an essential role in the formation of lipofibroblasts during late lung development
Expression of Fibroblast Growth Factor 10 is correlated with poor prognosis in gastric adenocarcinoma.
FGF10 has a role in protecting neuron against oxygen-glucose deprivation injury through inducing heme oxygenase-1 (show HMOX1 Proteins)
Data identify autocrine activation of FGF signaling as an essential mechanism in promoting Pten-deficient skin tumors.
precursor of the hormone Irisin (show FNDC5 Proteins) (FNCD5) were abundantly expressed in all three fat depots, along with fibroblast growth factors (FGF) FGF1 (show FGF1 Proteins), FGF7 (show FGF7 Proteins) and FGF10, whereas, FGF19 (show FGF19 Proteins) and FGF21 (show FGF21 Proteins) were undetectable.
The therapeutic potential of the FGF10 treatment.
FGF10 plays an important role for tumor growth by both paracrine and autocrine manner.
The findings show that immunohistochemistry with FGF10, FGFR2b, or SHH (show SHH Proteins) could be useful in differentiating CCAM (show CEACAM1 Proteins) from type I PPB (show HTN1 Proteins), when a child presents with a focal cystic lung lesion.
Paracrine FGF10 signaling stimulates the differentiation of human stem cell into urothelial cells.
Decreased Fgf10 mRNA levels lead to congenital lung defects, which are compatible with postnatal survival, but which compromise the ability of the lungs to cope with sub-lethal hyperoxic injury.
Fgf10 enhances the formation of tissue-engineered small intestine.
Lhx9 (show LHX9 Proteins) expression overlapped markedly with FGF10 expression cells in the limb mesenchyme and was associated with proliferative cells of the progress zone.
Hypoplasia of the salivary glands led to a significant reduction in saliva (show RAG1AP1 Proteins) production in Fgf10 heterozygous adult mice
Hoxc8 (show HOXC8 Proteins) initiates an ectopic mammary program by regulating Fgf10 and Tbx3 (show TBX3 Proteins) expression and Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling
BMP4 (show BMP4 Proteins) promotes activation of FGF7 (show FGF7 Proteins) and FGF10 signaling, leading to an increase in proliferative basal cell population in developing skin.
novel allele of Alx4 (show ALX4 Proteins) results in reduced Fgf10 expression and failure of eyelid fusion in mice
regulates regional cardiomyocyte proliferation in the foetal heart through a FOXO3 (show FOXO3 Proteins)/p27(kip1 (show CDKN1B Proteins)) pathway
Stromal Fgf10 and Bmp8a (show BMP8A Proteins) serve as potential paracrine factors for estrogen-dependent regulation of epithelial proliferation in the uterus.
We found no difference between treatments regarding embryo production, developmental speed, and gene expression. CONCLUSION: In conclusion, the presence of FGF10 during IVM had no effect on embryo production, developmental speed, and gene expression.
The present data suggest a role for FGF10 in the control of fetal folliculogenesis in cattle.
BMP15 (show BMP15 Proteins) and FGF10 stimulate expansion of in cumulus-oocyte complexes by driving glucose metabolism toward hyaluronic acid production and controlling gene expression in the ovulatory cascade.
FGF10 and its receptor FGFR2b are more expressed in subordinate follicles; FGF10 acts as an important regulator of follicular growth in cattle.
These data support a role for FGF10 and fibroblast growth factor receptor 2B in signaling to granulosa cells from theca cells and/or the oocyte.(fibroblast growth factor receptor 2B)
FGF10 mRNA expression did not change during functional luteolysis, whereas FGFR2B mRNA abundance decreased significantly at 2, 4, and 12 hr after PGF2alpha, and returned to pretreatment levels for the period 24-64 hr post-PGF2alpha
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.
, fibroblast growth factor 10
, keratinocyte growth factor 2
, produced by fibroblasts of urinary bladder lamina propria
, obg-like ATPase 1