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FGF10 Protein

FGF10 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90% as determined by Tris-Bis PAGE
Catalog No. ABIN7274614
  • Target See all FGF10 Proteins
    FGF10 (Fibroblast Growth Factor 10 (FGF10))
    Protein Type
    Recombinant
    Origin
    • 11
    • 4
    • 4
    Human
    Source
    • 16
    • 2
    • 1
    Escherichia coli (E. coli)
    Sequence
    Gln38-Ser208
    Purity
    > 90% as determined by Tris-Bis PAGE
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 0.299 nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product FGF10 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in 20 mM Tris, 150 mM NaCl ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    4 °C,-80 °C
    Storage Comment
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    FGF10 (Fibroblast Growth Factor 10 (FGF10))
    Alternative Name
    FGF10 (FGF10 Products)
    Synonyms
    fgf10 Protein, fgf-10 Protein, wu:fd11d03 Protein, zgc:109774 Protein, FGF10 Protein, AEY17 Protein, BB213776 Protein, Fgf-10 Protein, Gsfaey17 Protein, FGF-10 Protein, fibroblast growth factor 10a Protein, fibroblast growth factor 10 Protein, fgf10a Protein, FGF10 Protein, fgf10 Protein, Fgf10 Protein
    Background
    FGF-10, KGF2,Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease.
    Molecular Weight
    19.3 kDa. The protein migrates to 25 kDa based on Tris-Bis PAGE result.
    UniProt
    O15520
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
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