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FGF10 Protein (AA 62-209)

FGF10 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Catalog No. ABIN2017799
  • Target See all FGF10 Proteins
    FGF10 (Fibroblast Growth Factor 10 (FGF10))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 62-209
    Origin
    • 12
    • 4
    • 3
    Mouse
    Source
    • 16
    • 2
    • 1
    Escherichia coli (E. coli)
    Characteristics
    ED50 < 10 ng/mL, measured by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of > 1.0x 10^5 units/mg.
    Purity
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product FGF10 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant mouse Fibroblast Growth Factor-10 (rmFGF-10) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmFGF-10 remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    Expiry Date
    6 months
  • Target
    FGF10 (Fibroblast Growth Factor 10 (FGF10))
    Alternative Name
    Fibroblast Growth Factor-10 (FGF-10) (FGF10 Products)
    Synonyms
    fgf10 Protein, fgf-10 Protein, wu:fd11d03 Protein, zgc:109774 Protein, FGF10 Protein, AEY17 Protein, BB213776 Protein, Fgf-10 Protein, Gsfaey17 Protein, FGF-10 Protein, fibroblast growth factor 10a Protein, fibroblast growth factor 10 Protein, fgf10a Protein, FGF10 Protein, fgf10 Protein, Fgf10 Protein
    Background
    Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF, and both KGF and FGF-10 activate the receptor FGFR2-IIIb. However, unlike KGF, which induces the proliferation and differentiation of various epithelial cells, FGF-10 is an essential factor for the budding and branching morphogenesis during multi-organ development via mesenchymal-epithelial interactions. FGF-10 is crucial for lung and limb development and is regulated by Shh during early development. Recombinant mouse Fibroblast Growth Factor-10 (rmFGF-10) produced in E. coli is a single non-glycosylated polypeptide chain containing 148 amino acids. A fully biologically active molecule, rmFGF-10 has a molecular mass of 17.0 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2
    Molecular Weight
    17.0 kDa, observed by reducing SDS-PAGE.
    UniProt
    O35565
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
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