Browse our anti-IGF1R (IGF1R) Antibodies

Full name:
anti-Insulin-Like Growth Factor 1 Receptor Antibodies (IGF1R)
On are 487 Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies from 33 different suppliers available. Additionally we are shipping IGF1R Kits (53) and IGF1R Proteins (42) and many more products for this protein. A total of 598 IGF1R products are currently listed.
A330103N21Rik, CD221, D930020L01, DKFZp469I0618, hyft, igf-1r, igf-ir, IGF1R, IGFIR, IGFIRC, IGFR, IGFR1, JTK13, xIGF-1R, xigf1r, xIGFR
list all antibodies Gene Name GeneID UniProt
IGF1R 3480 P08069
IGF1R 25718 P24062
IGF1R 16001 Q60751

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Top referenced anti-IGF1R Antibodies

  1. Human Polyclonal IGF1R Primary Antibody for EIA, IHC (p) - ABIN359877 : Song, Barnes, Zhang, Bao, Kumar, Santen: The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 5 references for 359877

  2. Human Polyclonal IGF1R Primary Antibody for IHC (p), WB - ABIN391990 : Zhao, Dupont, Yakar, Karas, LeRoith: PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells. in Oncogene 2004 (PubMed)
    Show all 5 references for 391990

  3. Human Monoclonal IGF1R Primary Antibody for Func, FACS - ABIN111141 : Hantel, Lewrick, Schneider, Zwermann, Perren, Reincke, Süss, Beuschlein: Anti insulin-like growth factor I receptor immunoliposomes: a single formulation combining two anticancer treatments with enhanced therapeutic efficiency. in The Journal of clinical endocrinology and metabolism 2010 (PubMed)
    Show all 4 references for 111141

  4. Human Monoclonal IGF1R Primary Antibody for FACS, IHC (p) - ABIN181732 : Hantel, Lewrick, Reincke, Süss, Beuschlein: Liposomal doxorubicin-based treatment in a preclinical model of adrenocortical carcinoma. in The Journal of endocrinology 2012 (PubMed)
    Show all 4 references for 181732

  5. Human Monoclonal IGF1R Primary Antibody for FACS - ABIN319437 : Li, Kato, Paz, Kasuya, Fujita-Yamaguchi: Two new monoclonal antibodies against the alpha subunit of the human insulin-like growth factor-I receptor. in Biochemical and biophysical research communications 1993 (PubMed)
    Show all 3 references for 319437

  6. Human Polyclonal IGF1R Primary Antibody for FACS, IF - ABIN652374 : Lu, Zi, Zhao, Pollak: Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells. in Biochemical and biophysical research communications 2003 (PubMed)
    Show all 3 references for 652374

  7. Human Polyclonal IGF1R Primary Antibody for IF (p), IHC (p) - ABIN802203 : Tang, Liao, Xu, Zhang, Liu, Deng, Jiang, Fu, Chen, Zhou: Estrogen and insulin-like growth factor 1 synergistically promote the development of lung adenocarcinoma in mice. in International journal of cancer. Journal international du cancer 2013 (PubMed)
    Show all 2 references for 802203

  8. Human Polyclonal IGF1R Primary Antibody for WB - ABIN616037 : Adams, Epa, Garrett, Ward: Structure and function of the type 1 insulin-like growth factor receptor. in Cellular and molecular life sciences : CMLS 2000 (PubMed)
    Show all 2 references for 616037

  9. Cow (Bovine) Polyclonal IGF1R Primary Antibody for IF, IHC - ABIN2792087 : Urano, Narusawa, Shiraki, Usui, Sasaki, Hosoi, Ouchi, Nakamura, Inoue: Association of a single nucleotide polymorphism in the insulin-like growth factor-1 receptor gene with spinal disc degeneration in postmenopausal Japanese women. in Spine 2008 (PubMed)
    Show all 2 references for 2792087

  10. Human Polyclonal IGF1R Primary Antibody for FACS, IF (p) - ABIN726575 : Hu, Li, Hu, Wu, Li, Meng: MicroRNA let-7a and let-7f as novel regulatory factors of the sika deer (Cervus nippon) IGF-1R gene. in Growth factors (Chur, Switzerland) 2014 (PubMed)
    Show all 2 references for 726575

More Antibodies against IGF1R Interaction Partners

Horse (Equine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. This study evaluated the expression of IGF-1 (show IGF1 Antibodies) receptor, insulin receptor (show INSR Antibodies) AND IGF-1 (show IGF1 Antibodies) in the lammelar tissue of horses with insulin (show INS Antibodies)-induced hyperinsulinemia.

  2. The laminar cell types expressing insulin receptor (show INSR Antibodies) and/or insulin-like growth factor-1 receptor and the effect of dietary carbohydrates on their expression are reported.

  3. Somatomedin (IGF-I (show IGF1 Antibodies)) is localized in equine spermatogenic and Leydig cells, and IGF-I receptor is present in spermatogonia, spermatocytes and Leydig cells.[IGF-I receptor]

Human Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. We found that the thyroid hormone receptor (show THRA Antibodies) (TRalpha (show THRA Antibodies) 3) has a differential expression profile. Thyroid hormone (show PTH Antibodies) is critical for normal brain development. Our results showed that there is a possible link between IGF1 (show IGF1 Antibodies)/IGF1R and the TRalpha (show THRA Antibodies) 3 and that over expression of IGF1R in RTT cells may be the cause of neurites improvement in neural RTT-derived neurons.

  2. Data show that the let-7c/miR (show MLXIP Antibodies)-99a/miR (show MLXIP Antibodies)-125b cluster controlled tumorigenesis by targeting IL-6 (show IL6 Antibodies), IL-6R and IGF1R.

  3. IGF1R expression may have prognostic relevance in penile squamous cell carcinoma

  4. High IGF1R expression is associated with bone metastasis in prostate cancer.

  5. the Runx2 (show RUNX2 Antibodies) knockdown cells displayed activation of AMP-activated protein kinase (AMPKalpha (show GRK4 Antibodies)), the sensor of cellular metabolism. Importantly, the Runx2 (show RUNX2 Antibodies) knockdown in bone-derived cells resulted in increased sensitivity to both Erk1/2 (show MAPK1/3 Antibodies) inhibition and AMPKalpha (show GRK4 Antibodies) activation by PD184161 and metformin, respectively, despite increased IGF-1Rbeta and AMPKalpha (show GRK4 Antibodies) levels.

  6. Overexpression of mutated K-RAS in gastrointestinal cancer cell lines led to more aggressive phenotypes, with increased proliferation, decreased apoptosis, and increased motility and invasion. IGF-1R blockade suppressed cell growth, colony formation, migration, and invasion, and up-regulated chemotherapy-induced apoptosis of gastrointestinal cancer cells, even when mutated K-RAS was over-expressed.

  7. IFITM2 (show IFITM2 Antibodies) promotes gastric cancer growth and metastasis via IGF1 (show IGF1 Antibodies)/IGF1R/STAT3 (show STAT3 Antibodies) signaling pathway.

  8. The authors found low levels of IGF1R expression and PTEN (show PTEN Antibodies)-negative status to correlate with resistance to IGF1R inhibition as a treatment for Human T-Cell Acute Lymphoblastic Leukemias.

  9. miR (show MLXIP Antibodies)-15b inhibits the progression of glioblastoma cells through targeting IGF1R, and miR (show MLXIP Antibodies)-15b can be recommended as a tumor suppressor in the progression of glioblastoma.

  10. our findings suggested that miR (show MLXIP Antibodies)-205 serves as a prognostic factor and suppresses proliferation and invasion by targeting insulin (show INS Antibodies)-like growth factor receptor (show RYK Antibodies) 1 in human cervical cancer. Thus, miR (show MLXIP Antibodies)-205/insulin (show INS Antibodies)-like growth factor receptor (show RYK Antibodies) 1 pathway may be of great benefit to cervical cancer patients

Pig (Porcine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. IGF-I (show IGF1 Antibodies), IGF-II, and IGFBP-3 (show IGFBP3 Antibodies) mRNA were positively correlated with IGF-IR from 50E to 180D, suggesting that the expression of IGF-system genes exhibits specific developmental patterns in the skeletal muscle tissues.

  2. IL-1beta (show IL1B Antibodies) impaired the actions of IGF-I (show IGF1 Antibodies) at a point distal to the IGF receptor

  3. IGF-1R is expressed in porcine somatostatin (show SST Antibodies)-containing islet D-cells

  4. This study suggests an association between the affinity of insulin (show INS Antibodies) receptors and number of IGF-1 (show IGF1 Antibodies) receptors with placental and/or fetal growth.

  5. mRNA expression of IGF-I receptor

Cow (Bovine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. A total of 1169 cows of 4 pure breeds (Polish Holstein Friesian, Montbeliarde, Jersey and Holstein Friesian) were genotyped. The T (IGF1R/e2/MspI) and G (IGF1R/e2/TaqI) alleles were found to be prevalent. 3 combinations of genotypes (TT/GG, TT/AG and CT/GG) were associated with the highest productivity (milk, protein and fat yields) among the breeds studied, as opposed to individuals carrying the worst CC/AA combination.

  2. study determined IGFR1 and PAPP-A (show PAPPA Antibodies) expression both in follicles at different stages of development and in ovarian cysts; data indicate that animals with cystic ovarian disease (COD (show SNRPB Antibodies)) have an altered regulation of the IGF system in the ovary and thus allow postulating IGFR1 expression and PAPP-A (show PAPPA Antibodies) secretion as a modulator of IGF1 (show IGF1 Antibodies) in cattle with COD (show SNRPB Antibodies)

  3. Results of the present study showed, for the first time, that the polymorphism in IGF1R is associated with superovulation traits, and indicated that the IGFIR gene can be used as a potential marker for donor selection.

  4. two SNPs in the coding region of the insulin-like growth factor 1 receptor gene may have a role in growth of Angus cattle

  5. insulin (show INS Antibodies)-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization

  6. The objective of this study was to estimate the allele and genotype frequencies of the IGF-IR/TaqI, m-calpain (show CAPN2 Antibodies)/HhaI, and UCP-3 (show UCP3 Antibodies)/BglI polymorphisms and to determine association between these polymorphisms and growth traits in Chinese indigenous cattle breed.

  7. Data describes the long-term changes to skeletal muscle growth and IGF1 (show IGF1 Antibodies), 2, 1R, and 2R mRNA expression in progeny after exposure to high and low levels of maternal nutrient intake during the first two trimesters of gestation in the bovine.

  8. Results do not support the premise that increased apoptosis associated with high levels of IGF1 (show IGF1 Antibodies) is mediated via downregulation of the IGF1R as previously found in preimplantation mouse embryos.

  9. IGF-I (show IGF1 Antibodies) down-regulated functional IGF-I receptor via GSK-3beta (show GSK3b Antibodies) inhibition and mTOR (show FRAP1 Antibodies) activation; constitutive activity of GSK-3beta (show GSK3b Antibodies) maintained IGF-I receptor level in nonstimulated cells.

  10. IGF-1 (show IGF1 Antibodies) and IGF-1r gene polymorphisms in East Anatolian Red and South Anatolian Red cattle breeds.

Mouse (Murine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. SUMOylation of IGF1R affects upstream mechanisms that control and coordinate expression of cell cycle regulators to increase cell cycle progression and proliferation.

  2. findings demonstrated that significant resistance of the brain to amyloid-beta can be achieved lifelong by suppressing neuronal IGF1R.

  3. Results found that glioblastoma tumors resistant to PDGFR (show PDGFRB Antibodies) inhibition required the expression and activation of the insulin receptor (IR (show INSR Antibodies))/insulin (show INS Antibodies) growth-like factor receptor (IGF1R) for tumor cell proliferation and survival.

  4. Conditional deletion of synaptotagmin-10 (show SYT10 Antibodies), the Ca(2 (show CA2 Antibodies)+) sensor for IGF1 (show IGF1 Antibodies) secretion from mitral cells, or deletion of IGF1 (show IGF1 Antibodies) receptor in the olfactory bulb prevented the socially relevant GABAergic long-term potentiation and impaired memory formation after social transmission of food preference.

  5. These results support the role of Igf1r in controlling the kinetics of cell proliferation and differentiation during pulmonary airway epithelial regeneration after injury.

  6. Although smaller than WT (wild type) mice, old-aged Igf1r(+/-) had increased adiposity and exhibit increased lipogenesis. We hypothesize that IGF-1 (show IGF1 Antibodies) resistance initially causes a transient increase in insulin (show INS Antibodies) signaling thereby promoting a lipogenic phenotype, which subsequently leads to insulin (show INS Antibodies) resistance.

  7. HASF is a novel ligand of IGF1R.

  8. Under nonpathological conditions, IGF-1 (show IGF1 Antibodies) regulates brain IGF-1R. Because baseline IGF-1R levels are rapidly restored, a tight control of brain IGF-1R expression seems to operate under physiological conditions.

  9. These findings highlight the sex-dependent and potentially detrimental effects of in utero smoke exposure on DNA methylation (show HELLS Antibodies) and Igf1 (show IGF1 Antibodies) and Igf1r mRNA levels.

  10. MicroRNA-99a inhibits insulin (show INS Antibodies)-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting IGF-1R and mTOR (show FRAP1 Antibodies) signaling.

IGF1R Antigen Profile

Antigen Summary

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

Alternative names and synonyms associated with IGF1R

  • insulin-like growth factor 1 receptor (IGF1R) antibody
  • insulin-like growth factor 1 receptor (Igf1r) antibody
  • insulin-like growth factor 1 receptor (igf1r) antibody
  • insulin-like growth factor I receptor (Igf1r) antibody
  • insulin-like growth factor I receptor (LOC780503) antibody
  • insulin-like growth factor I receptor (igf-ir) antibody
  • A330103N21Rik antibody
  • CD221 antibody
  • D930020L01 antibody
  • DKFZp469I0618 antibody
  • hyft antibody
  • igf-1r antibody
  • igf-ir antibody
  • IGF1R antibody
  • IGFIR antibody
  • IGFIRC antibody
  • IGFR antibody
  • IGFR1 antibody
  • JTK13 antibody
  • xIGF-1R antibody
  • xigf1r antibody
  • xIGFR antibody

Protein level used designations for IGF1R

IGF-I receptor , insulin-like growth factor I receptor , soluble IGF1R variant 1 , soluble IGF1R variant 2 , insulin-like growth factor receptor tyrosine kinase , insulin-like growth factor-I receptor , type 1 IGF receptor , tyrosine kinase , IGF-1 receptor , insulin-like growth factor 1 receptor beta subunit , insulin-like growth factor receptor 1 , insulin-like growth factor-1 receptor , receptor tyrosine kinase , insulin-like growth factor 1 receptor , line 186 , insulin-like growth factor-1 receptor beta subunit , xIGF-1R , xIGFR

3480 Homo sapiens
25718 Rattus norvegicus
281848 Bos taurus
395889 Gallus gallus
397350 Sus scrofa
442951 Canis lupus familiaris
453676 Pan troglodytes
100172156 Pongo abelii
100329112 Xenopus (Silurana) tropicalis
16001 Mus musculus
100020095 Monodelphis domestica
780503 Ovis aries
100136427 Salmo salar
398022 Xenopus laevis
100055698 Equus caballus
100734840 Cavia porcellus
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