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Browse our anti-IGF1R (IGF1R) Antibodies

Full name:
anti-Insulin-Like Growth Factor 1 Receptor Antibodies (IGF1R)
On are 427 Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies from 29 different suppliers available. Additionally we are shipping IGF1R Kits (37) and IGF1R Proteins (32) and many more products for this protein. A total of 512 IGF1R products are currently listed.
A330103N21Rik, CD221, D930020L01, DKFZp469I0618, hyft, IGF-1R, IGF1R, IGFIR, IGFIRC, IGFR, IGFR1, JTK13, xIGF-1R, xigf1r, xIGFR
list all antibodies Gene Name GeneID UniProt
IGF1R 3480 P08069
IGF1R 25718 P24062
IGF1R 16001 Q60751

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Top referenced anti-IGF1R Antibodies

  1. Human Polyclonal IGF1R Primary Antibody for EIA, IHC (p) - ABIN359877 : Song, Barnes, Zhang, Bao, Kumar, Santen: The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 5 references for ABIN359877

  2. Human Polyclonal IGF1R Primary Antibody for IHC (p), WB - ABIN391990 : Zhao, Dupont, Yakar, Karas, LeRoith: PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells. in Oncogene 2004 (PubMed)
    Show all 5 references for ABIN391990

  3. Human Monoclonal IGF1R Primary Antibody for Func, FACS - ABIN111141 : Hantel, Lewrick, Schneider, Zwermann, Perren, Reincke, Süss, Beuschlein: Anti insulin-like growth factor I receptor immunoliposomes: a single formulation combining two anticancer treatments with enhanced therapeutic efficiency. in The Journal of clinical endocrinology and metabolism 2010 (PubMed)
    Show all 4 references for ABIN111141

  4. Human Monoclonal IGF1R Primary Antibody for FACS, IHC (p) - ABIN181732 : Hantel, Lewrick, Reincke, Süss, Beuschlein: Liposomal doxorubicin-based treatment in a preclinical model of adrenocortical carcinoma. in The Journal of endocrinology 2012 (PubMed)
    Show all 3 references for ABIN181732

  5. Human Monoclonal IGF1R Primary Antibody for FACS - ABIN319437 : Li, Kato, Paz, Kasuya, Fujita-Yamaguchi: Two new monoclonal antibodies against the alpha subunit of the human insulin-like growth factor-I receptor. in Biochemical and biophysical research communications 1993 (PubMed)
    Show all 3 references for ABIN319437

  6. Human Polyclonal IGF1R Primary Antibody for FACS, IF - ABIN652374 : Lu, Zi, Zhao, Pollak: Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells. in Biochemical and biophysical research communications 2003 (PubMed)
    Show all 3 references for ABIN652374

  7. Human Polyclonal IGF1R Primary Antibody for WB - ABIN616037 : Adams, Epa, Garrett, Ward: Structure and function of the type 1 insulin-like growth factor receptor. in Cellular and molecular life sciences : CMLS 2000 (PubMed)
    Show all 2 references for ABIN616037

  8. Chicken Polyclonal IGF1R Primary Antibody for IHC, WB - ABIN2792087 : Urano, Narusawa, Shiraki, Usui, Sasaki, Hosoi, Ouchi, Nakamura, Inoue: Association of a single nucleotide polymorphism in the insulin-like growth factor-1 receptor gene with spinal disc degeneration in postmenopausal Japanese women. in Spine 2008 (PubMed)
    Show all 2 references for ABIN2792087

  9. Human Polyclonal IGF1R Primary Antibody for IF (p), IHC (p) - ABIN726575 : Hu, Li, Hu, Wu, Li, Meng: MicroRNA let-7a and let-7f as novel regulatory factors of the sika deer (Cervus nippon) IGF-1R gene. in Growth factors (Chur, Switzerland) 2014 (PubMed)
    Show all 2 references for ABIN726575

  10. Human Polyclonal IGF1R Primary Antibody for WB - ABIN197244 : Li, Ferber, Miura, Baserga: Mitogenicity and transforming activity of the insulin-like growth factor-I receptor with mutations in the tyrosine kinase domain. in The Journal of biological chemistry 1995 (PubMed)

More Antibodies against IGF1R Interaction Partners

Horse (Equine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. This study evaluated the expression of IGF-1 (show IGF1 Antibodies) receptor, insulin receptor (show INSR Antibodies) AND IGF-1 (show IGF1 Antibodies) in the lammelar tissue of horses with insulin (show INS Antibodies)-induced hyperinsulinemia.

  2. The laminar cell types expressing insulin receptor (show INSR Antibodies) and/or insulin-like growth factor-1 receptor and the effect of dietary carbohydrates on their expression are reported.

  3. Somatomedin (IGF-I (show IGF1 Antibodies)) is localized in equine spermatogenic and Leydig cells, and IGF-I receptor is present in spermatogonia, spermatocytes and Leydig cells.[IGF-I receptor]

Human Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. Positive correlations indicated probable cross-talk between the IGF-IR-mediated and adiponectin (show ADIPOQ Antibodies)-mediated signaling pathways.

  2. IGF1R is a direct target of miR (show MLXIP Antibodies)-494 in epithelial ovarian carcinoma cells. miR (show MLXIP Antibodies)-494 overexpression inhibited IGF1R expression and its downstream signal protein (show KLK7 Antibodies) expression. IGF1R downregulation has similar effects to miR (show MLXIP Antibodies)-494 overexpression on EOC cells, and overexpression of IGF1R effectively rescued the inhibition of overexpressed miR (show MLXIP Antibodies)-494 in EOC cells. miR (show MLXIP Antibodies)-494 directly binds the IGF1R 3'-UTR (show UTS2R Antibodies).

  3. identification of IGF-1R in odontogenic myxoma is shared with numerous tumours and indicates the ability of these tumour cells to respond to growth factors

  4. NANOG (show NANOG Antibodies) was regulated by extracellular IGF signaling pathway via STAT3 (show STAT3 Antibodies) phosphorylation in colorectal cancer (CRC (show CALR Antibodies)). This coincides with that IGF receptor IGF-1R is often increasing expressed in malignant metastasis colon cancer. Taken together, our data define the crucial functions of IGF/STAT3 (show STAT3 Antibodies)/NANOG (show NANOG Antibodies)/Slug (show SNAI2 Antibodies) signaling axis in the progression of CRC (show CALR Antibodies)

  5. This study suggests IGF1R as a potential biomarker of improved clinical outcome in HR+ve breast cancer patients treated with exemestane. Adding metformin to exemestane treatment may add to this effect

  6. We present multiplexed RO assays for an IGF1R-EGFR (show EGFR Antibodies) bispecific antibody (Bs-Ab) and a CTLA4 (show CTLA4 Antibodies)-Ig recombinant fusion protein to demonstrate key considerations for accurate RO assessment.

  7. IGF1 (show IGF1 Antibodies) pro-forms can induce breast cancer cell proliferation via the IGF1R, independent from the mature IGF1 (show IGF1 Antibodies) form.

  8. p53 (show TP53 Antibodies) R273H mutation unleashes the inhibition effect of miR (show MLXIP Antibodies)-30a on IGF-1R expression, thus leading to elevated activation of IGF-1R-AKT (show AKT1 Antibodies) signaling cascade in tumor cells.

  9. miR (show MLXIP Antibodies)-214 significantly blocked IGF-1R-forced renal cancer cell proliferation, which was reversed by expression of 3'UTR (show UTS2R Antibodies)-less IGF-1R and constitutively active mTORC1.

  10. The findings suggest that miR (show MLXIP Antibodies)-98 inhibits cancer cell growth and metastasis by direct targeting IGF1R, implicating miR (show MLXIP Antibodies)-98 as a novel potential therapeutic target for oral squamous cell carcinoma (OSCC).

Pig (Porcine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. IGF-I (show IGF1 Antibodies), IGF-II, and IGFBP-3 (show IGFBP3 Antibodies) mRNA were positively correlated with IGF-IR from 50E to 180D, suggesting that the expression of IGF-system genes exhibits specific developmental patterns in the skeletal muscle tissues.

  2. IL-1beta (show IL1B Antibodies) impaired the actions of IGF-I (show IGF1 Antibodies) at a point distal to the IGF receptor

  3. IGF-1R is expressed in porcine somatostatin (show SST Antibodies)-containing islet D-cells

  4. This study suggests an association between the affinity of insulin (show INS Antibodies) receptors and number of IGF-1 (show IGF1 Antibodies) receptors with placental and/or fetal growth.

  5. mRNA expression of IGF-I receptor

Cow (Bovine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. study determined IGFR1 and PAPP-A (show PAPPA Antibodies) expression both in follicles at different stages of development and in ovarian cysts; data indicate that animals with cystic ovarian disease (COD (show SNRPB Antibodies)) have an altered regulation of the IGF system in the ovary and thus allow postulating IGFR1 expression and PAPP-A (show PAPPA Antibodies) secretion as a modulator of IGF1 (show IGF1 Antibodies) in cattle with COD (show SNRPB Antibodies)

  2. Results of the present study showed, for the first time, that the polymorphism in IGF1R is associated with superovulation traits, and indicated that the IGFIR gene can be used as a potential marker for donor selection.

  3. two SNPs in the coding region of the insulin-like growth factor 1 receptor gene may have a role in growth of Angus cattle

  4. insulin (show INS Antibodies)-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization

  5. The objective of this study was to estimate the allele and genotype frequencies of the IGF-IR/TaqI, m-calpain (show CAPN2 Antibodies)/HhaI, and UCP-3 (show UCP3 Antibodies)/BglI polymorphisms and to determine association between these polymorphisms and growth traits in Chinese indigenous cattle breed.

  6. Data describes the long-term changes to skeletal muscle growth and IGF1 (show IGF1 Antibodies), 2, 1R, and 2R mRNA expression in progeny after exposure to high and low levels of maternal nutrient intake during the first two trimesters of gestation in the bovine.

  7. Results do not support the premise that increased apoptosis associated with high levels of IGF1 (show IGF1 Antibodies) is mediated via downregulation of the IGF1R as previously found in preimplantation mouse embryos.

  8. IGF-I (show IGF1 Antibodies) down-regulated functional IGF-I receptor via GSK-3beta (show GSK3b Antibodies) inhibition and mTOR (show FRAP1 Antibodies) activation; constitutive activity of GSK-3beta (show GSK3b Antibodies) maintained IGF-I receptor level in nonstimulated cells.

  9. IGF-1 (show IGF1 Antibodies) and IGF-1r gene polymorphisms in East Anatolian Red and South Anatolian Red cattle breeds.

  10. granulosa cell clustering is accompanied by marked increases in FSHr (show FSHR Antibodies), IGF-1r, and p450 arom (show CYP19A1 Antibodies) expression, and precedes induction and subsequent peak E2 production

Mouse (Murine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. Macrophage IGF1R signaling suppresses macrophage and foam cell accumulation in lesions and reduces plaque vulnerability, providing a novel mechanism whereby IGF-1 (show IGF1 Antibodies) exerts antiatherogenic effects in ApoE (show APOE Antibodies) knockout mice.

  2. study recognized the promotion of miR (show MLXIP Antibodies)-223 level by AGE-BSA treatment in osteoblast-like MC3T3-E1 cells. The promoted miR (show MLXIP Antibodies)-223 targeted IGF-1R and mediated the AGE-BSA-induced apoptosis in MC3T3-E1 cells.

  3. osterix (show SP7 Antibodies) is a downstream target of IGF1R in chondrocytes.

  4. NF-kappaB (show NFKB1 Antibodies)-miR (show MLXIP Antibodies)-195/497-Igf1r/Insr (show INSR Antibodies)-Ccnd2 (show CCND2 Antibodies)/Ccne1 (show CCNE1 Antibodies) plays important roles in myogenesis.

  5. this study, we have characterized epigenetic changes following pregnancy and found that Igf1r and other IGF family members are hypermethylated and downregulated.

  6. IGF1R signaling was necessary for DC-mediated T-ALL survival.

  7. mitochondria, activated by IGF-1R signaling, constitute a critical regulator of information processing in hippocampal neurons.

  8. IGF1R is involved in osteoblast differentiation during fracture repair and it plays an important role in coordinating chondrocyte, osteoclast, and endothelial responses that contribute to endochondral bone formation required for normal fracture repair

  9. ectopic down-regulation of IGF1R reversed the protective effect of miR (show MLXIP Antibodies)-100 down-regulation on H2O2-induced apoptosis, revealing that miR (show MLXIP Antibodies)-100 regulates cardiomyocyte apoptosis through the association of IGF1R.

  10. Data (including data from studies in knockout mice) suggest that Igf1r plays role in cardiomyocytes during ventricular remodeling of aging; deletion of Igf1r in cardiomyocytes attenuates cardiac aging in male mice.

IGF1R Antigen Profile

Antigen Summary

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

Alternative names and synonyms associated with IGF1R

  • insulin-like growth factor 1 receptor (IGF1R) antibody
  • insulin-like growth factor 1 receptor (igf1r) antibody
  • insulin-like growth factor 1 receptor (Igf1r) antibody
  • insulin-like growth factor I receptor (Igf1r) antibody
  • A330103N21Rik antibody
  • CD221 antibody
  • D930020L01 antibody
  • DKFZp469I0618 antibody
  • hyft antibody
  • IGF-1R antibody
  • IGF1R antibody
  • IGFIR antibody
  • IGFIRC antibody
  • IGFR antibody
  • IGFR1 antibody
  • JTK13 antibody
  • xIGF-1R antibody
  • xigf1r antibody
  • xIGFR antibody

Protein level used designations for IGF1R

insulin-like growth factor 1 receptor , IGF-I receptor , insulin-like growth factor I receptor , soluble IGF1R variant 1 , soluble IGF1R variant 2 , insulin-like growth factor-1 receptor beta subunit , xIGF-1R , xIGFR , insulin-like growth factor receptor tyrosine kinase , insulin-like growth factor-I receptor , type 1 IGF receptor , tyrosine kinase , IGF-1 receptor , insulin-like growth factor 1 receptor beta subunit , insulin-like growth factor receptor 1 , insulin-like growth factor-1 receptor , receptor tyrosine kinase , line 186

100055698 Equus caballus
453676 Pan troglodytes
100172156 Pongo abelii
100329112 Xenopus (Silurana) tropicalis
100020095 Monodelphis domestica
3480 Homo sapiens
25718 Rattus norvegicus
398022 Xenopus laevis
395889 Gallus gallus
397350 Sus scrofa
281848 Bos taurus
442951 Canis lupus familiaris
100734840 Cavia porcellus
16001 Mus musculus
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