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Browse our anti-IGF1R (IGF1R) Antibodies

Full name:
anti-Insulin-Like Growth Factor I Receptor Antibodies (IGF1R)
On www.antibodies-online.com are 0 Insulin-Like Growth Factor I Receptor (IGF1R) Antibodies from different suppliers available. A total of 0 IGF1R products are currently listed.
Synonyms:
A330103N21Rik, CD221, D930020L01, hyft, IGF-1R, igf-ir, IGFIR, IGFIRC, IGFR, JTK13
list all antibodies Gene Name GeneID UniProt
Anti-Human IGF1R IGF1R 3480 P08069
Anti-Rat IGF1R IGF1R 25718 P24062
Anti-Mouse IGF1R IGF1R 16001 Q60751

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More Antibodies against IGF1R Interaction Partners

Human Insulin-Like Growth Factor I Receptor (IGF1R) interaction partners

  1. Previously characterized disease-causing mutations in IGF2, IGF1R, IGF2R (show IGF2R Antibodies), or IGFALS (show IGFALS Antibodies) all were found in the general population but with allele frequencies of <1:30,000.

  2. These results indicate that mutagenesis and skin carcinogenesis in IGF-1 (show IGF1 Antibodies)-deficient geriatric skin may be caused by defects in multiple cellular responses to UVB-induced DNA damage, including through a failure to properly suppress DNA synthesis on UVB-damaged DNA templates.

  3. Authors identified Insulin (show INS Antibodies) Growth Factor (IGF)1 (show IGF1 Antibodies) receptor as the signal positively regulated by TGFbeta (show TGFB1 Antibodies) implicated in ovarian tumor cell proliferation.

  4. IGF-1R downregulation may have a regulatory impact after initiation of hepatic lineage commitment.

  5. Our findings imply that APBB1 (show APBB1 Antibodies) plays an important role in the maintenance of EMT (show ITK Antibodies)-associated CSC-like properties and gamma-radiation resistance via activation of IGF1Rbeta/AKT (show AKT1 Antibodies)/GSK3beta (show GSK3b Antibodies) pathway in lung cancer cells, highlighting APBB1 (show APBB1 Antibodies) as a potential target for therapeutic cancer treatment.

  6. a straightforward protocol for production of recombinant IGF-II and prepared six IGF-II analogs with IGF-I-like mutations. All modified molecules exhibit significantly reduced affinity toward IR-A, particularly the analogs with a Pro-Gln insertion in the C-domain. Moreover, one of the analogs has enhanced binding affinity for IGF-1R due to a synergistic effect of the Pro-Gln insertion and S29N point mutation.

  7. These results indicate that miR (show MLXIP Antibodies)-139 is capable of inhibiting chondrocyte proliferation and migration, thus being a possible therapeutic target for OA. The mechanism of miR (show MLXIP Antibodies)-139 in chondrocytes may be related to its regulation on EIF4G2 (show EIF4G2 Antibodies) and IGF1R.

  8. Results indicate that recombinant lentiviral vectors provided an efficient and stable knockdown of insulin-like growth factor 1 receptor (IGF-1R) providing useful tool for IGF-1R pathway studies.

  9. Findings indicated both cezanne (show OTUD7B Antibodies)-1 and IGF1R expressions were negative independent predictive factors for the prognosis of lung adenocarcinoma, respectively. There was a close positive interrelationship between cezanne (show OTUD7B Antibodies)-1 and IGF1R expression.

  10. an IGF-1 (show IGF1 Antibodies)/IGF-1R loop could play a role in the tumorigenesis and progression of schwannomas via an autocrine-paracrine mechanism.

Mouse (Murine) Insulin-Like Growth Factor I Receptor (IGF1R) interaction partners

  1. MicroRNA-99a inhibits insulin (show INS Antibodies)-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting IGF-1R and mTOR (show FRAP1 Antibodies) signaling.

  2. These results indicated that IGF1R may increase cell viability under hypoxic conditions by promoting autophagy and scavenging reactive oxygen species production, which is closed with PI3K/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway.

  3. When charged with hypoxia-ischemia, mutant brains with deleted IGF-1 (show IGF1 Antibodies) receptor were broadly protected from cell damage, neuroinflammation and cerebral edema.

  4. Suggest that overexpression of IGF-IR or IRA (show INSR Antibodies) isoform, as homodimers or as part of IRA (show INSR Antibodies)/IGF-IR hybrid receptors, confers a stronger migratory capability to vascular smooth muscle cells and might occur in early stages of atherosclerotic process.

  5. Macrophage IGF1R signaling suppresses macrophage and foam cell accumulation in lesions and reduces plaque vulnerability, providing a novel mechanism whereby IGF-1 (show IGF1 Antibodies) exerts antiatherogenic effects in ApoE (show APOE Antibodies) knockout mice.

  6. study recognized the promotion of miR (show MLXIP Antibodies)-223 level by AGE-BSA treatment in osteoblast-like MC3T3-E1 cells. The promoted miR (show MLXIP Antibodies)-223 targeted IGF-1R and mediated the AGE-BSA-induced apoptosis in MC3T3-E1 cells.

  7. osterix (show SP7 Antibodies) is a downstream target of IGF1R in chondrocytes.

  8. NF-kappaB (show NFKB1 Antibodies)-miR (show MLXIP Antibodies)-195/497-Igf1r/Insr (show INSR Antibodies)-Ccnd2 (show CCND2 Antibodies)/Ccne1 (show CCNE1 Antibodies) plays important roles in myogenesis.

  9. this study, we have characterized epigenetic changes following pregnancy and found that Igf1r and other IGF family members are hypermethylated and downregulated.

  10. IGF1R signaling was necessary for DC-mediated T-ALL survival.

IGF1R Antigen Profile

Antigen Summary

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

Alternative names and synonyms associated with IGF1R

  • insulin-like growth factor I receptor (LOC780503) antibody
  • insulin-like growth factor I receptor (igf-ir) antibody
  • insulin-like growth factor 1 receptor (IGF1R) antibody
  • insulin-like growth factor 1 receptor (Igf1r) antibody
  • insulin-like growth factor I receptor (Igf1r) antibody
  • A330103N21Rik antibody
  • CD221 antibody
  • D930020L01 antibody
  • hyft antibody
  • IGF-1R antibody
  • igf-ir antibody
  • IGFIR antibody
  • IGFIRC antibody
  • IGFR antibody
  • JTK13 antibody

Protein level used designations for IGF1R

insulin-like growth factor I receptor , IGF-I receptor , soluble IGF1R variant 1 , soluble IGF1R variant 2 , insulin-like growth factor 1 receptor , line 186

GENE ID SPECIES
780503 Ovis aries
100136427 Salmo salar
3480 Homo sapiens
25718 Rattus norvegicus
16001 Mus musculus
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