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Browse our anti-IGF1R (IGF1R) Antibodies

Full name:
anti-Insulin-Like Growth Factor I Receptor Antibodies (IGF1R)
On www.antibodies-online.com are 44 Insulin-Like Growth Factor I Receptor (IGF1R) Antibodies from 6 different suppliers available. Additionally we are shipping IGF1R Kits (4) and and many more products for this protein. A total of 49 IGF1R products are currently listed.
Synonyms:
A330103N21Rik, CD221, D930020L01, hyft, IGF-1R, igf-ir, IGFIR, IGFIRC, IGFR, JTK13
list all antibodies Gene Name GeneID UniProt
IGF1R 3480 P08069
IGF1R 25718 P24062
IGF1R 16001 Q60751

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Most Popular Reactivities for anti-IGF1R (IGF1R) Antibodies

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anti-Human IGF1R Antibodies:

anti-Rat (Rattus) IGF1R Antibodies:

anti-Mouse (Murine) IGF1R Antibodies:

All available anti-IGF1R Antibodies

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Top referenced anti-IGF1R Antibodies

  1. Human Polyclonal IGF1R Primary Antibody for IHC, WB - ABIN363154 : Counillon, Pouysségur: The expanding family of eucaryotic Na(+)/H(+) exchangers. in The Journal of biological chemistry 2000 (PubMed)
    Show all 5 references for ABIN363154

  2. Human Polyclonal IGF1R Primary Antibody for IHC, WB - ABIN363153 : OConnor, Kauffmann-Zeh, Liu, Lehar, Evan, Baserga, Blättler: Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis. in Molecular and cellular biology 1997 (PubMed)
    Show all 5 references for ABIN363153

  3. Human Polyclonal IGF1R Primary Antibody for WB - ABIN871427 : Adams, Epa, Garrett, Ward: Structure and function of the type 1 insulin-like growth factor receptor. in Cellular and molecular life sciences : CMLS 2000 (PubMed)
    Show all 4 references for ABIN871427

  4. Human Polyclonal IGF1R Primary Antibody for IF, IHC - ABIN1355850 : Kasuya, Paz, Maddux, Goldfine, Hefta, Fujita-Yamaguchi: Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification. in Biochemistry 1994 (PubMed)
    Show all 3 references for ABIN1355850

  5. Human Polyclonal IGF1R Primary Antibody for WB - ABIN362638 : Li, Ferber, Miura, Baserga: Mitogenicity and transforming activity of the insulin-like growth factor-I receptor with mutations in the tyrosine kinase domain. in The Journal of biological chemistry 1995 (PubMed)
    Show all 3 references for ABIN362638

  6. Human Polyclonal IGF1R Primary Antibody for IF, WB - ABIN362040 : Han, Quirion, Zheng: WITHDRAWN: Glutamate Attenuates IGF-1 Receptor Signaling via NR2B containing NMDA Receptors 3 and neuronal Nitric Oxide Synthase. in Biochemical and biophysical research communications 2011 (PubMed)
    Show all 2 references for ABIN362040

  7. Human Polyclonal IGF1R Primary Antibody for IF, IHC - ABIN362636 : Yamamoto, Oshima, Yoshihara, Nishi, Arai, Inui, Kaneko, Nozawa, Adachi, Rino, Masuda, Imada: Clinical significance of immunohistochemical expression of insulin-like growth factor-1 receptor and matrix metalloproteinase-7 in resected non-small cell lung cancer. in Experimental and therapeutic medicine 2012 (PubMed)
    Show all 2 references for ABIN362636

More Antibodies against IGF1R Interaction Partners

Human Insulin-Like Growth Factor I Receptor (IGF1R) interaction partners

  1. these results demonstrated that miR (show MLXIP Antibodies)-217 plays a tumor suppressor role in human epithelial ovarian cancer by directly targeting IGF1R gene, suggesting a new potential therapeutic target in epithelial ovarian cancer .

  2. IGF1R overexpression lead to an increase of cell survival and suppressed cell apoptosis, IGF1R silencing mediated by RNAi abrogate this response of NCI-H446 cells.

  3. mTORC2 (show CRTC2 Antibodies) promotes rapamycin- and ligand-induced type I insulin (show INS Antibodies)-like growth factor receptor (show RYK Antibodies) / insulin receptor (show INSR Antibodies) phosphorylation.

  4. The results suggest that severe intra-uterine growth differences (birth weight discordance >20%) are associated with methylation changes in the IGF1R gene in adulthood, independent of genetic effects

  5. Our study demonstrates that the IGF1R/p110b/AKT (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) axis confers resistance to BYL719 in PIK3CA (show PIK3CA Antibodies) mutant breast cancers.

  6. we found a SNP (rs2016347) in IGF1R as a potential predictive marker for chemotherapy efficacy in breast cancer patients treated with TAC (show IL2RA Antibodies)

  7. HRD1 (show SYVN1 Antibodies) interacted with IGF-1R and promoted its ubiquitination and degradation by the proteasome

  8. High expression of IGF1R is associated with breast cancer.

  9. Anoikis resistance of oestrogen-responsive breast cancer cells depends upon IGF activation of the type I IGF receptor and PI3-kinase (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway.

  10. Data suggest that temozolomide (TMZ) resistance associates with insulin like growth factor 1 (show IGF1 Antibodies) (IGF-1R) activation, and that simultaneous or prior IGF-1R inhibitors (IGF-1Ri) caused less effective chemo-sensitization.

Mouse (Murine) Insulin-Like Growth Factor I Receptor (IGF1R) interaction partners

  1. osterix (show SP7 Antibodies) is a downstream target of IGF1R in chondrocytes.

  2. NF-kappaB (show NFKB1 Antibodies)-miR (show MLXIP Antibodies)-195/497-Igf1r/Insr (show INSR Antibodies)-Ccnd2 (show CCND2 Antibodies)/Ccne1 (show CCNE1 Antibodies) plays important roles in myogenesis.

  3. this study, we have characterized epigenetic changes following pregnancy and found that Igf1r and other IGF family members are hypermethylated and downregulated.

  4. IGF1R signaling was necessary for DC-mediated T-ALL survival.

  5. mitochondria, activated by IGF-1R signaling, constitute a critical regulator of information processing in hippocampal neurons.

  6. IGF1R is involved in osteoblast differentiation during fracture repair and it plays an important role in coordinating chondrocyte, osteoclast, and endothelial responses that contribute to endochondral bone formation required for normal fracture repair

  7. ectopic down-regulation of IGF1R reversed the protective effect of miR (show MLXIP Antibodies)-100 down-regulation on H2O2-induced apoptosis, revealing that miR (show MLXIP Antibodies)-100 regulates cardiomyocyte apoptosis through the association of IGF1R.

  8. Data (including data from studies in knockout mice) suggest that Igf1r plays role in cardiomyocytes during ventricular remodeling of aging; deletion of Igf1r in cardiomyocytes attenuates cardiac aging in male mice.

  9. The IGF1R ectodomain maintains an autoinhibited state in which the transmembrane domains are held apart.

  10. Data (including data from studies in knockout mice) suggest that, in aging and metabolic stress such as insulin (show INS Antibodies) resistance/pregnancy, pancreatic beta-cells exhibit sex differences in Igf2/Igf1r signaling during beta-cell expansion/mass adaptation.

IGF1R Antigen Profile

Antigen Summary

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

Alternative names and synonyms associated with IGF1R

  • insulin-like growth factor I receptor (LOC780503) antibody
  • insulin-like growth factor I receptor (igf-ir) antibody
  • insulin-like growth factor 1 receptor (IGF1R) antibody
  • insulin-like growth factor 1 receptor (Igf1r) antibody
  • insulin-like growth factor I receptor (Igf1r) antibody
  • A330103N21Rik antibody
  • CD221 antibody
  • D930020L01 antibody
  • hyft antibody
  • IGF-1R antibody
  • igf-ir antibody
  • IGFIR antibody
  • IGFIRC antibody
  • IGFR antibody
  • JTK13 antibody

Protein level used designations for IGF1R

insulin-like growth factor I receptor , IGF-I receptor , soluble IGF1R variant 1 , soluble IGF1R variant 2 , insulin-like growth factor 1 receptor , line 186

GENE ID SPECIES
780503 Ovis aries
100136427 Salmo salar
3480 Homo sapiens
25718 Rattus norvegicus
16001 Mus musculus
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