Browse our anti-MME (MME) Antibodies

Full name:
anti-Membrane Metallo-Endopeptidase Antibodies (MME)
On are 642 Membrane Metallo-Endopeptidase (MME) Antibodies from 37 different suppliers available. Additionally we are shipping MME Kits (43) and MME Proteins (39) and many more products for this protein. A total of 747 MME products are currently listed.
6030454K05Rik, AV378681, C85356, CAK, CALLA, CD10, CD167, DDR, EDDR1, HGK2, MCK10, MME, Mmel, Nep, NTRK4, PTK3, PTK3A, RTK6, SFE, TRKE

All available anti-MME Antibodies

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Top referenced anti-MME Antibodies

  1. Human Polyclonal MME Primary Antibody for FACS, IHC (p) - ABIN391499 : Dakka, Bellaoui, Bouzid, Khattab, Bakri, Benjouad: CD10 AND CD34 expression in childhood acute lymphoblastic leukemia in Morocco: clinical relevance and outcome. in Pediatric hematology and oncology 2009 (PubMed)
    Show all 4 references for 391499

  2. Human Polyclonal MME Primary Antibody for IF, WB - ABIN391500 : Shipp, Vijayaraghavan, Schmidt, Masteller, DAdamio, Hersh, Reinherz: Common acute lymphoblastic leukemia antigen (CALLA) is active neutral endopeptidase 24.11 ("enkephalinase"): direct evidence by cDNA transfection analysis. in Proceedings of the National Academy of Sciences of the United States of America 1989 (PubMed)
    Show all 4 references for 391500

  3. Human Monoclonal MME Primary Antibody for FACS - ABIN119106 : Biddle, Haruta, Seon, Henderson, Sarcione: In vitro and in vivo cytotoxic activity of anti-human leukemia monoclonal antibodies SN5c and SN6 daunorubicin conjugates. in Leukemia research 1989 (PubMed)
    Show all 4 references for 119106

  4. Human Polyclonal MME Primary Antibody for IHC (p), WB - ABIN654151 : Wang, Wang, Chen, Bennett, Dickson, Wang: Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain. in Journal of neurochemistry 2010 (PubMed)
    Show all 2 references for 654151

  5. Human Monoclonal MME Primary Antibody for IHC (p) - ABIN1687426 : Seracchioli, Raimondo, Di Donato, Leonardi, Spagnolo, Paradisi, Montanari, Caprara, Zannoni: Histological evaluation of ureteral involvement in women with deep infiltrating endometriosis: analysis of a large series. in Human reproduction (Oxford, England) 2015 (PubMed)
    Show all 2 references for 1687426

  6. Human Monoclonal MME Primary Antibody for WB - ABIN659195 : Ikenaga, Ohuchida, Mizumoto, Cui, Kayashima, Morimatsu, Moriyama, Nakata, Fujita, Tanaka: CD10+ pancreatic stellate cells enhance the progression of pancreatic cancer. in Gastroenterology 2010 (PubMed)
    Show all 2 references for 659195

  7. Human Monoclonal MME Primary Antibody for FACS, IHC (fro) - ABIN119108 : Matsuzaki, Haruta, Fukukawa, Barcos, Seon: Unique epitopes of common acute lymphoblastic leukemia antigen detected by new monoclonal antibodies. in Cancer research 1987 (PubMed)
    Show all 2 references for 119108

  8. Human Monoclonal MME Primary Antibody for FACS - ABIN1105723 : Pan, Cardarelli, Nieder, Pickford, Gangwar, King, Yarranton, Buckman, Roscoe, Zhou, Salles, Chen, Horgan, Wang, Nguyen, Bebbington: CD10 is a key enzyme involved in the activation of tumor-activated peptide prodrug CPI-0004Na and novel analogues: implications for the design of novel peptide prodrugs for the therapy of CD10+ tumors. in Cancer research 2003 (PubMed)

More Antibodies against MME Interaction Partners

Pig (Porcine) Membrane Metallo-Endopeptidase (MME) interaction partners

  1. Neutral endopeptidase 24.11 and DPP-IV (show DPP4 Antibodies) is superior to DPP-IV (show DPP4 Antibodies) inhibition alone in preserving intact GLP-1 (show GCG Antibodies), which implies possibility that the combination has therapeutic potential.

  2. This study provides evidence that NEP 24.11 is an important mediator of the degradation of both endogenous and exogenous glucagon (show GCG Antibodies) in vivo.

Human Membrane Metallo-Endopeptidase (MME) interaction partners

  1. CD10 is a necessary component conferring the L1 effects in CRC (show CALR Antibodies) cells. The identification of gene expression patterns of L1-domain-specific point mutations may provide novel markers and targets for interfering with L1-mediated CRC (show CALR Antibodies) progression.

  2. High CD10 expression is associated with lymphoma in Waldeyer ring.

  3. Rare Variants in MME, Encoding Metalloprotease (show ADAM8 PLURAL_@27060@) Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies

  4. Reduced DDR1 (show DDR1 Antibodies) expression may be implicated in impaired melanocyte adhesion process involved in vitiligo (show MITF Antibodies) pathogenesis

  5. CD10 down expression in follicular lymphoma correlates with gastrointestinal lesion involving the stomach and large intestine

  6. data demonstrate that TGF-beta1 (show TGFB1 Antibodies) favors linear invadosome formation through the expressions of both the inducers, such as collagen and LOXL2 (show LOXL2 Antibodies), and the components such as DDR1 (show DDR1 Antibodies) and MT1-MMP (show MMP14 Antibodies) of linear invadosomes in cancer cells. Meanwhile, our data uncover a new TGF-beta1 (show TGFB1 Antibodies)-dependent regulation of DDR1 (show DDR1 Antibodies) expression.

  7. DDR1 (show DDR1 Antibodies) overexpression promoted GC cell proliferation (p < 0.05), migration (p < 0.01), and invasion (p < 0.01), and accelerated the growth (p < 0.05) as well as the microvessel formation (p < 0.01) of transplantation tumor in nude mice.

  8. Our results suggest that DDR1 (show DDR1 Antibodies) is both a prognostic marker for renal clear cell carcinoma and a potential functional target for therapy

  9. High CD10 expression is associated with Basal cell carcinoma of the skin.

  10. Study concludes that non-canonical DDR1 (show DDR1 Antibodies) signaling enables breast cancer cells to exploit the ubiquitous interstitial matrix component collagen I to undergo metastatic reactivation in multiple target organs.

Mouse (Murine) Membrane Metallo-Endopeptidase (MME) interaction partners

  1. Mmp12 (show MMP12 Antibodies) is expressed early following corneal epithelial injury with highest expression levels at 8 h after injury and lower expression levels at 4 and 8 days after injury. We investigated whether MMP12 (show MMP12 Antibodies) has an effect on the rate of epithelial repair and cell migration using in vivo and in vitro scratch assays performed on WT and Mmp12 (show MMP12 Antibodies)(-/-) mice

  2. Rare Variants in MME, Encoding Metalloprotease (show ADAMTS7 PLURAL_@27060@) Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies

  3. MMP-12 (show MMP12 Antibodies) produced by macrophages infiltrating into glomeruli contributed to the degradation of collagen type IV (show COL4 Antibodies) and fibronectin (show FN1 Antibodies).

  4. MMP12 (show MMP12 Antibodies) causes arterial stiffening in mice and suggest that it functions similarly in humans.

  5. These results suggest that MMP-12 (show MMP12 Antibodies) production during emphysema exacerbation results in increased mortality and disease progression.

  6. study found significant increases of MMP-3 (show MMP3 Antibodies) and MMP-12 (show MMP12 Antibodies) mRNA levels and MMP12 (show MMP12 Antibodies) zymographic activities in response to Cryptococcus neoformans infection but not C. gattii infection

  7. The results suggest that pulmonary C fiber involvement in long-term airway inflammation and airway hyperresponsiveness occurred at least partially via modulating MMP-12 (show MMP12 Antibodies), and the activation of PAR2 (show F2RL1 Antibodies) might be related to MMP-12 (show MMP12 Antibodies) production.

  8. MMP-12 (show MMP12 Antibodies) up-regulation mediated by SARM (show SARM1 Antibodies)-TRIF (show RNF138 Antibodies) signaling pathway contributes to IFN-gamma (show IFNG Antibodies)-independent airway inflammation and AHR (show AHR Antibodies) post RSV infection in nude mice.

  9. MMP-12 (show MMP12 Antibodies) and MMP-13 (show MMP13 Antibodies) alter strain K infection in mice and play a role in inflammatory regulation by modulating cytokine levels.

  10. Amyloid beta (Abeta (show APP Antibodies))-degrading effects of overexpressed neprilysin can block deleterious BACE1 (show BACE Antibodies)-elevating mechanisms that accelerate Abeta (show APP Antibodies) production

MME Antigen Profile

Antigen Summary

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.

Alternative names and synonyms associated with MME

  • membrane metallo-endopeptidase (MME) antibody
  • discoidin domain receptor tyrosine kinase 1 (DDR1) antibody
  • matrix metallopeptidase 12 (Mmp12) antibody
  • membrane metallo endopeptidase (Mme) antibody
  • membrane metallo-endopeptidase (Mme) antibody
  • 6030454K05Rik antibody
  • AV378681 antibody
  • C85356 antibody
  • CAK antibody
  • CALLA antibody
  • CD10 antibody
  • CD167 antibody
  • DDR antibody
  • EDDR1 antibody
  • HGK2 antibody
  • MCK10 antibody
  • MME antibody
  • Mmel antibody
  • Nep antibody
  • NTRK4 antibody
  • PTK3 antibody
  • PTK3A antibody
  • RTK6 antibody
  • SFE antibody
  • TRKE antibody

Protein level used designations for MME

membrane metallo-endopeptidase , enkephalinase , neutral endopeptidase , membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase) , membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) , neprilysin , neprilysin-410 short isoform , CD167 antigen-like family member A , PTK3A protein tyrosine kinase 3A , cell adhesion kinase , epithelial discoidin domain-containing receptor 1 , mammary carcinoma kinase 10 , neuroepithelial tyrosine kinase , neurotrophic tyrosine kinase, receptor, type 4 , protein-tyrosine kinase RTK-6 , tyrosine kinase DDR , tyrosine-protein kinase CAK , MME , MMP-12 , macrophage elastase , macrophage metalloelastase , macrophage-metalloelastase , matrix metalloproteinase 12 , matrix metalloproteinase-12 , atriopeptidase , common acute lymphoblastic leukemia antigen , neutral endopeptidase 24.11 , skin fibroblast elastase , common acute lymphocytic leukemia antigen , membrane metallo-endopeptidase variant 1 , membrane metallo-endopeptidase variant 2 , membrane metallo endopeptidase , membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase) , NEP

497058 Sus scrofa
425031 Gallus gallus
477120 Canis lupus familiaris
780 Homo sapiens
17381 Mus musculus
17380 Mus musculus
4311 Homo sapiens
24590 Rattus norvegicus
100511536 Sus scrofa
100009251 Oryctolagus cuniculus
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