Browse our PTK7 Proteins (PTK7)

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PTK7 Protein tyrosine Kinase 7 Proteins (PTK7)
On are 20 PTK7 Protein tyrosine Kinase 7 (PTK7) Proteins from 7 different suppliers available. Additionally we are shipping PTK7 Antibodies (146) and PTK7 Kits (1) and many more products for this protein. A total of 175 PTK7 products are currently listed.
8430404F20Rik, CCK-4, CCK4, chz, KLG, mPTK7/CCK4, PTK7, Srf
list all proteins Gene Name GeneID UniProt
PTK7 5754 Q13308
PTK7 301242  
PTK7 71461 Q8BKG3

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PTK7 Proteins (PTK7) by Origin

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Top referenced PTK7 Proteins

  1. Human PTK7 Protein expressed in Wheat germ - ABIN1316785 : Li, Wang, Feng, Tong, Tang: Highly sensitive and homogeneous detection of membrane protein on a single living cell by aptamer and nicking enzyme assisted signal amplification based on microfluidic droplets. in Analytical chemistry 2014 (PubMed)

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Human PTK7 Protein tyrosine Kinase 7 (PTK7) interaction partners

  1. Our data indicate that PTK7 protein expression is associated with the prognosis of oral tongue squamous cell carcinoma

  2. PTK7 expression was correlated with tumor differentiation (P=0.027), lymph node metastasis (P=0.005), distant metastasis (P=0.001) and TNM (show ODZ1 Proteins) stage (P=0.028) of colorectal cancer patients

  3. High PTK7 expression is associated with radioresistance in esophageal squamous cell carcinoma.

  4. PTK7 enriches in self-renewing, multipotent stem cells of the human colon.

  5. findings implicate PTK7 as a risk factor for NTDs and provide additional evidence for a pathogenic role of PCP (show PRCP Proteins) signaling in these malformations

  6. overexpression in PTK7-negative cancer cells led to increased metastatic events. PTK7 expression thus represents a potential prognostic biomarker and a novel therapeutic target in CRC (show CALR Proteins).

  7. data demonstrates that PTK7 regulates the activity of KDR (show KDR Proteins) biphasically by inducing oligomerization of KDR (show KDR Proteins) molecules at lower concentrations and by surrounding KDR (show KDR Proteins) molecules at higher concentrations.

  8. PTK7 regulates Id1 (show ID1 Proteins) expression in CD44 (show CD44 Proteins)-high glioma cell lines. Targeting PTK7 could be an effective strategy for treating glioma with high CD44 (show CD44 Proteins) expression.

  9. The results suggest that N-acylethanolamine acid amidase (show NAAA Proteins) and protein tyrosine kinase 7 may be used as potential tissue biomarkers to avoid overtreatment of non-aggressive prostate cancer

  10. Expression level of PTK7 was significantly decreased from benign to malignant ovarian epithelial tumors. survival analysis showed that patients with negative expression of PTK7 protein had poorer outcome than those with positive expression.

Mouse (Murine) PTK7 Protein tyrosine Kinase 7 (PTK7) interaction partners

  1. In a Ptk7-deficient mouse strain, loss of Ptk7 leads to a diminished pool of hematopoietic stem cells but does not affect in vitro or in vivo differentiation. This is correlated with increased quiescence and reduced homing abilities of Ptk7-deficient hematopoietic stem and progenitor cells.

  2. Data suggest that protein tyrosine kinase 7 (PTK7) is essential for Wolffian duct morphogenesis and male fertility.

  3. data demonstrates that PTK7 regulates the activity of KDR (show KDR Proteins) biphasically by inducing oligomerization of KDR (show KDR Proteins) molecules at lower concentrations and by surrounding KDR (show KDR Proteins) molecules at higher concentrations.

  4. PTK7 expression plays an important role in the invasiveness of intrahepatic cholangiocarcinoma cells.

  5. Planar polarity of neural cell motility and intercalation requires Ptk7 function.

  6. acts in conjunction with the noncanonical Wnt pathway to orient epithelial planar cell polarity through modulation of myosin II-based contractile tension between supporting cells and hair cells

  7. The tyrosine kinase receptor (show KDR Proteins), PTK7, is implicated in beta-catenin (show CTNNB1 Proteins)-dependent developmental processes.

  8. These findings illustrate a novel and pivotal role for Cdx (show CDX1 Proteins) function upstream of Ptk7 and neural tube closure in vertebrates.

  9. Chuzhoi mutation, that causes multiple abnormalities maps, to Chromosome 17 and carries a splice site mutation in Ptk7 and causes disruption of Ptk7 protein expression.

  10. Ptk7 mRNA was expressed at high levels in lung and un-pregnant uterus among adult tissues, and in the tail, limbs, somites, gut (show GUSB Proteins), and craniofacial regions among embryonic tissues, and suggest that PTK7 plays multiple roles in embryonic development.

PTK7 Protein Profile

Protein Summary

This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with PTK7

  • PTK7 protein tyrosine kinase 7 (PTK7)
  • protein tyrosine kinase 7 (PTK7)
  • protein tyrosine kinase 7 (Ptk7)
  • PTK7 protein tyrosine kinase 7 (Ptk7)
  • 8430404F20Rik protein
  • CCK-4 protein
  • CCK4 protein
  • chz protein
  • KLG protein
  • mPTK7/CCK4 protein
  • PTK7 protein
  • Srf protein

Protein level used designations for PTK7

PTK7 protein tyrosine kinase 7 , inactive tyrosine-protein kinase 7 , tyrosine-protein kinase-like 7-like , colon carcinoma kinase 4 , pseudo tyrosine kinase receptor 7 , tyrosine-protein kinase-like 7 , serum response factor , protein chuzhoi , protein-tyrosine kinase 7 , receptor tyrosine kinase-like protein , kinase-like protein

462708 Pan troglodytes
481808 Canis lupus familiaris
514819 Bos taurus
699791 Macaca mulatta
100067287 Equus caballus
100401966 Callithrix jacchus
100435506 Pongo abelii
100484485 Ailuropoda melanoleuca
100598905 Nomascus leucogenys
5754 Homo sapiens
301242 Rattus norvegicus
71461 Mus musculus
421257 Gallus gallus
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