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PTK7 Protein (AA 39-712) (His tag)

PTK7 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274039
  • Target See all PTK7 Proteins
    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 39-712
    Origin
    • 15
    • 6
    • 3
    • 1
    • 1
    • 1
    Cynomolgus
    Source
    • 13
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PTK7 protein is labelled with His tag.
    Purpose
    Cynomolgus PTK7/CCK4 Protein
    Sequence
    Ala39-Thr712
    Characteristics
    Recombinant Cynomolgus PTK7/CCK4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala39-Thr712.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product PTK7 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
    Alternative Name
    PTK7 (PTK7 Products)
    Synonyms
    PTK7 Protein, CCK-4 Protein, CCK4 Protein, Srf Protein, 8430404F20Rik Protein, chz Protein, mPTK7/CCK4 Protein, KLG Protein, protein tyrosine kinase 7 (inactive) Protein, protein tyrosine kinase 7 Protein, PTK7 protein tyrosine kinase 7 Protein, PTK7 Protein, Ptk7 Protein
    Background
    Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling.
    Molecular Weight
    75.73 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
    UniProt
    A0A2K5VNI5
    Pathways
    RTK Signaling, Tube Formation
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