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PTPN11 Proteins

(Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].

recommended

PTPN11 Protein (AA 1-460) (GST tag) (ABIN1316822)

PTPN11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

PTPN11 Protein (His tag) (ABIN7197591)

PTPN11 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active

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recommended

PTPN11 Protein (AA 2-521) (His tag) (ABIN7505167)

PTPN11 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.

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PTPN11 Proteins by Origin

Find PTPN11 Proteins for a variety of species such as anti-Human PTPN11, anti-Rat PTPN11, anti-Mouse PTPN11. The species listed below are among those available. Click on a link to go to the corresponding products.

PTPN11 Proteins by Source

Here you will find PTPN11 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PTPN11 Proteins by Protein Type

Here you can find PTPN11 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

PTPN11 Proteins by Application

Find PTPN11 Proteins validated for a specific application such as SDS, WB, ELISA, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PTPN11 Proteins by Biological Activity

Find PTPN11 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular PTPN11 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

PTPN11 Protein (AA 1-460) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1316822

Quantity 10 μg

Datasheet Datasheet

PTPN11 Protein (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7197591

Quantity 200 μg

Datasheet Datasheet

PTPN11 Protein (AA 2-521) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7505167

Quantity 100 μg

Datasheet Datasheet

PTPN11 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7579078

Quantity 100 μg

Datasheet Datasheet

PTPN11 Protein (His tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7397573

Quantity 100 μg

Datasheet Datasheet

PTPN11 Protein (AA 1-460) (His tag)

Reactivity Human

Source Baculovirus infected Insect Cells

Validations

Cat. No. ABIN5855056

Quantity 50 μg

Datasheet Datasheet

PTPN11 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2730110

Quantity 20 μg

Datasheet Datasheet

PTPN11 Protein

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6382351

Quantity 1 mg

Datasheet Datasheet

PTPN11 Protein (AA 2-597) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1474246

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our PTPN11 Proteins

Jo, Park, Lee, Ahn, Kim, Park, Choi: "SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes." in: PLoS ONE, Vol. 9, Issue 3, pp. e91582, (2014) (PubMed).

Aliases for PTPN11 Proteins

protein tyrosine phosphatase, non-receptor type 11 (PTPN11) Proteins
protein tyrosine phosphatase, non-receptor type 11 (Ptpn11) Proteins
protein tyrosine phosphatase, non-receptor type 11 S homeolog (ptpn11.S) Proteins
protein tyrosine phosphatase, non-receptor type 11, a (ptpn11a) Proteins
protein tyrosine phosphatase, non-receptor type 11, b (ptpn11b) Proteins
2700084A17Rik Proteins
AW536184 Proteins
BPTP3 Proteins
bptp3 Proteins
CFC Proteins
cfc Proteins
fa14b09 Proteins
NS1 Proteins
ns1 Proteins
PTP-1D Proteins
ptp-2 Proteins
PTP1D Proteins
PTP2C Proteins
ptp2c Proteins
ptpn11 Proteins
ptpn11-a Proteins
ptpn11-b Proteins
SAP-2 Proteins
SH-PTP2 Proteins
SH-PTP3 Proteins
SHP-2 Proteins
shp-2 Proteins
SHP2 Proteins
Shp2 Proteins
shp2 Proteins
Syp Proteins
SYP Proteins
wu:fa14b09 Proteins
wu:fi24f03 Proteins
zgc:55388 Proteins
zgc:63553 Proteins

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PTPN11 Proteins by Origin

PTPN11 Proteins by Source

PTPN11 Proteins by Protein Type

PTPN11 Proteins by Application

PTPN11 Proteins by Biological Activity

Popular PTPN11 Proteins

Latest Publications for our PTPN11 Proteins

Aliases for PTPN11 Proteins

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