PTPN11 Proteins
(Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
| Catalog no. | Product | Reactivity | Host / Clonality | Application | Price & lead time |
|---|---|---|---|---|---|
| PTPN11 Protein (AA 1-460) (GST tag) | Human | Wheat germ |
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$475.39
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| PTPN11 Protein (AA 1-460) (His tag) | Human | Baculovirus infected Insect Cells |
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$676.92
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| PTPN11 Protein (AA 1-593) (His tag) | Mouse | HEK-293 Cells |
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$1,388.86
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| PTPN11 Protein (Q257L, T253M) (GST tag) | Human | Baculovirus infected Insect Cells |
|
$327.08
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| PTPN11 Protein (GST tag) | Human | Escherichia coli (E. coli) |
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$327.08
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| PTPN11 Protein (GST tag) | Human | Baculovirus infected Insect Cells |
|
$327.08
View price
|
|
| PTPN11 Protein (AA 1-593) (His tag) | Human | Baculovirus infected Insect Cells |
|
$734.62
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|
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| PTPN11 Protein (AA 219-525) (His tag) | Human | Escherichia coli (E. coli) |
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$510.30
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| PTPN11 Protein (AA 1-525) (His tag) | Human | Escherichia coli (E. coli) |
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$449.07
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| PTPN11 Protein (AA 2-521) (His tag) | Human | Escherichia coli (E. coli) |
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$1,902.46
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| PTPN11 Protein (Myc-DYKDDDDK Tag) | Human | HEK-293 Cells |
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$956.40
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| PTPN11 Protein (AA 2-597) (His tag) | Rat | Yeast |
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$1,773.34
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| PTPN11 Protein (AA 1-593) (His tag) | Human | Bacteria |
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$500.50
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| PTPN11 Protein (His tag) | Human | Escherichia coli (E. coli) |
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$478.00
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| PTPN11 Protein (His tag) | Rat | Escherichia coli (E. coli) |
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$534.26
View price
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Protein
- AP (Affinity Purification: Listed application)
- AA (Antibody Array: Listed application)
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
1 reference - Origin
- Human
- Host
- Wheat germ
- Protein Type
- Recombinant
Catalog No. ABIN1316822
$475.39
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
(More quantities available)
Shipping to:
United States
Delivery in 11 to 14 Business Days
Protein
- SDS (SDS-PAGE: Validation image available)
- Origin
- Human
- Host
- Baculovirus infected Insect Cells
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN5855056
$676.92
Plus shipping costs $50.00, if applicable $20.00 dry ice
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 18 Business Days
Protein
- WB (Western Blotting: Validation image available)
- Origin
- Mouse
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Biological Activity
- Active
Catalog No. ABIN7197591
$1,388.86
Plus shipping costs $50.00
200 μg
Shipping to:
United States
Delivery in 11 to 15 Business Days
Protein
- WB (Western Blotting: Listed application)
- PAA (Phosphatase Activity Assay: Listed application)
- Origin
- Human
- Host
- Baculovirus infected Insect Cells
- Protein Type
- Recombinant
- Biological Activity
- Active
Catalog No. ABIN7857155
$327.08
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
Protein
- WB (Western Blotting: Listed application)
- PAA (Phosphatase Activity Assay: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Biological Activity
- Active
Catalog No. ABIN7857157
$327.08
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
Protein
- WB (Western Blotting: Listed application)
- PAA (Phosphatase Activity Assay: Listed application)
- Origin
- Human
- Host
- Baculovirus infected Insect Cells
- Protein Type
- Recombinant
- Biological Activity
- Active
Catalog No. ABIN7857156
$327.08
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- EAA (Enzyme Activity Assay: Listed application)
- Origin
- Human
- Host
- Baculovirus infected Insect Cells
- Protein Type
- Recombinant
- Purity
- > 90 %
- Biological Activity
- Active
Catalog No. ABIN7677205
$734.62
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 18 Business Days
Protein
- WB (Western Blotting: Listed application)
- ELISA (ELISA: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7665139
$510.30
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 15 to 20 Business Days
Protein
- WB (Western Blotting: Listed application)
- ELISA (ELISA: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7665140
$449.07
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 15 to 20 Business Days
Protein
- Imm (Immunogen: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669501
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to:
United States
Delivery in 11 to 15 Business Days
Protein
- WB (Western Blotting: Validation image available)
- AbP (Antibody Production: Listed application)
- STD (Standard: Listed application)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2730110
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to:
United States
Delivery in 11 to 12 Business Days
Protein
- ELISA (ELISA: Listed application)
- Origin
- Rat
- Host
- Yeast
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN7585767
$1,773.34
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 60 to 72 Business Days
Catalog No. ABIN7818368
$500.50
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to:
United States
Delivery in 7 to 10 Business Days
Protein
- WB (Western Blotting: Listed application)
- ELISA (ELISA: Listed application)
- SDS (SDS-PAGE: Listed application)
- Imm (Immunogen: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
Catalog No. ABIN7943957
$478.00
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 8 to 12 Business Days
Protein
- WB (Western Blotting: Listed application)
- SDS (SDS-PAGE: Listed application)
- Origin
- Rat
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN6382351
$534.26
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 10 to 20 Business Days
Latest Publications for our PTPN11 Proteins
: "SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes." in: PLoS ONE, Vol. 9, Issue 3, pp. e91582, (2014) (PubMed).
Aliases for PTPN11 Proteins
protein tyrosine phosphatase, non-receptor type 11 (PTPN11) Proteinsprotein tyrosine phosphatase, non-receptor type 11 (Ptpn11) Proteins
protein tyrosine phosphatase, non-receptor type 11 S homeolog (ptpn11.S) Proteins
protein tyrosine phosphatase, non-receptor type 11, a (ptpn11a) Proteins
protein tyrosine phosphatase, non-receptor type 11, b (ptpn11b) Proteins
2700084A17Rik Proteins
AW536184 Proteins
BPTP3 Proteins
bptp3 Proteins
CFC Proteins
cfc Proteins
fa14b09 Proteins
NS1 Proteins
ns1 Proteins
PTP-1D Proteins
ptp-2 Proteins
PTP1D Proteins
PTP2C Proteins
ptp2c Proteins
ptpn11 Proteins
ptpn11-a Proteins
ptpn11-b Proteins
SAP-2 Proteins
SH-PTP2 Proteins
SH-PTP3 Proteins
SHP-2 Proteins
shp-2 Proteins
SHP2 Proteins
Shp2 Proteins
shp2 Proteins
Syp Proteins
SYP Proteins
wu:fa14b09 Proteins
wu:fi24f03 Proteins
zgc:55388 Proteins
zgc:63553 Proteins
Did you look for something else?
- PTPN1 Proteins
- PTPMT1 Proteins
- PTPLB Proteins
- PTPLAD1 Proteins
- PTPLA Proteins
- PTPDC1 Proteins
- PTP4A3 Proteins
- PTP4A2 Proteins
- PTP4A1 Proteins
- PTOV1 Proteins
- PTMA Proteins
- PTK7 Proteins
- PTK6 Proteins
- PTK2B Proteins
- PTH1R Proteins
- PTH Proteins
- PTGS1 Proteins
- PTGR2 Proteins
- PTGR1 Proteins
- PTGIS Proteins
- PTPN12 Proteins
- PTPN13 Proteins
- PTPN14 Proteins
- PTPN18 Proteins
- PTPN2 Proteins
- PTPN20 Proteins
- PTPN21 Proteins
- PTPN22 Proteins
- PTPN3 Proteins
- PTPN4 Proteins
- PTPN5 Proteins
- PTPN7 Proteins
- PTPN9 Proteins
- PTPRA Proteins
- PTPRB Proteins
- PTPRD Proteins
- PTPRE Proteins
- PTPRF Proteins
- PTPRG Proteins
- PTPRH Proteins
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