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Browse our ROR1 Proteins (ROR1)

Full name:
Receptor Tyrosine Kinase-Like Orphan Receptor 1 Proteins (ROR1)
On are 43 Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) Proteins from 13 different suppliers available. Additionally we are shipping ROR1 Antibodies (124) and ROR1 Kits (9) and many more products for this protein. A total of 186 ROR1 products are currently listed.
2810404D04Rik, 9530021D13Rik, dJ537F10.1, mRor1, nmf267, Nr1f1, Ntrkr1, RGD1559469, ROR1, ROR2, ROR3, sg, staggerer, tmgc26
list all proteins Gene Name GeneID UniProt
ROR1 19883 P51448
ROR1 4919 Q01973
ROR1 362550  

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ROR1 Proteins (ROR1) by Origin

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Top referenced ROR1 Proteins

  1. Human ROR1 Protein expressed in HEK-293 Cells - ABIN2181700 : Reddy, Phatak, Pleasure: Human neural tissues express a truncated Ror1 receptor tyrosine kinase, lacking both extracellular and transmembrane domains. in Oncogene 1996 (PubMed)
    Show all 4 references for ABIN2181700

  2. Mouse (Murine) ROR1 Protein expressed in HEK-293 Cells - ABIN2181703 : Greenman, Stephens, Smith, Dalgliesh, Hunter, Bignell, Davies, Teague, Butler, Stevens, Edkins, OMeara, Vastrik, Schmidt, Avis, Barthorpe, Bhamra, Buck, Choudhury, Clements, Cole, Dicks, Forbes, Gray et al.: Patterns of somatic mutation in human cancer genomes. ... in Nature 2007 (PubMed)
    Show all 4 references for ABIN2181703

  3. Human ROR1 Protein expressed in HEK-293 Cells - ABIN2731082 : Hojjat-Farsangi, Jeddi-Tehrani, Daneshmanesh, Mozaffari, Moshfegh, Hansson, Razavi, Sharifian, Rabbani, Österborg, Mellstedt, Shokri: Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia. in PLoS ONE 2015 (PubMed)

  4. Human ROR1 Protein expressed in Baculovirus infected Insect Cells - ABIN2006026 : Rose, Herskovic, Behm, Westman: Precessation treatment with nicotine patch significantly increases abstinence rates relative to conventional treatment. in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2009 (PubMed)

More Proteins for ROR1 Interaction Partners

Mouse (Murine) Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) interaction partners

  1. Ror1 is crucial for spiral ganglion neurons to innervate auditory hair cells. Impairment of ROR1 function largely affects development of the inner ear and hearing in humans and mice.

  2. Although Ror1-mutant mice show no apparent defects in ureteric bud (UB) formation, Ror1; Ror2 (show ROR2 Proteins)-double-mutant mice exhibit either defects in UB outgrowth and branching morphogenesis, associated with the loss of the MM from the UB domain, or ectopic formation of the UB.

  3. RORalpha regulates pathologic retinal angiogenesis by modulating SOCS3 (show SOCS3 Proteins)-dependent inflammation

  4. This study showed that spontaneous Rora (show RORA Proteins) mutations causing cerebellar pathology are impaired in motor functions during the neonatal period.

  5. the inhibition of NF-kappaB (show NFKB1 Proteins) by melatonin, but not that of NLRP3 (show NLRP3 Proteins), was blunted in RORalpha (sg/sg) mice, indicating that functional RORalpha transcription factor is necessary for the initiation of the innate immune response against inflammation.

  6. Rora (show RORA Proteins) induces the mRNA level of antioxidant enzymes, superoxide dismutase 2 (show SOD2 Proteins) and glutathione peroxidase 1 (show GPX1 Proteins), through the Rora (show RORA Proteins) response elements located in the upstream promoters of Sod2 (show SOD2 Proteins) and Gpx1 (show GPX1 Proteins).

  7. The nuclear receptors retinoic acid receptor (show RARA Proteins)-related orphan receptors-alpha and gammat (RORalpha and RORgammat) play critical roles in the development of TH17 cells.

  8. RORalpha is a transcriptional activator of insulin (show INS Proteins).

  9. Corl2/Skor2 has a role in regulating cerebellar Purkinje cell differentiation in a pathway involving RORalpha

  10. RORalpha is a key regulator of diurnal rhythm and fasting induction of CYP8B1 (show CYP8B1 Proteins), which regulates bile acid composition and serum and liver cholesterol levels.

Human Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) interaction partners

  1. Data show that ROR1 contributes to melanoma progression by promoting cell growth and migration.

  2. High ROR1-DNAJC6 (show DNAJC6 Proteins) expression is associated with neoplasms.

  3. we aim to present an overview of the efforts and scientific achievements in targeting ROR family, particularly ROR-1, for the diagnosis and treatment of chronic lymphocytic leukemia --{REVIEW}

  4. that strong ROR1 expression might be an independent adverse prognostic factor in triple negative breast cancer

  5. Ror1 is crucial for spiral ganglion neurons to innervate auditory hair cells. Impairment of ROR1 function largely affects development of the inner ear and hearing in humans and mice.

  6. targeting ROR1 can induce differentiation of cancer stem cells and inhibit metastasis in glioblastoma; in addition, ROR1 may be used as a potential marker for glioblastoma stem cells as well as a potential target for glioblastoma stem cell therapy

  7. expression of ROR1 was significantly higher in colorectal carcinoma tissues than in tumor-adjacent tissues

  8. these findings revealed that miR382 inhibits migration and invision by targeting ROR1 through regulating EMT (show ITK Proteins) in ovarian cancer, and might serve as a tumor suppressor in ovarian cancer.

  9. Data show that silencing receptor tyrosine kinases (RTKs) ROR2 (show ROR2 Proteins) and ROR1 has a strong inhibitory effect on the ability of ovarian cancer cells to proliferate, migrate and invade.

  10. the b-catenin-independent WNT (show WNT2 Proteins) score correlated with reduced overall survival only in the metastasized situation . This is in line with the in vitro results of the alternative WNT (show WNT2 Proteins) receptors ROR1 and ROR2 (show ROR2 Proteins), which foster invasion

ROR1 Protein Profile

Protein Summary

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with ROR1

  • receptor tyrosine kinase-like orphan receptor 1 (ROR1)
  • RAR-related orphan receptor alpha (Rora)
  • receptor tyrosine kinase-like orphan receptor 1 (Ror1)
  • 2810404D04Rik protein
  • 9530021D13Rik protein
  • dJ537F10.1 protein
  • mRor1 protein
  • nmf267 protein
  • Nr1f1 protein
  • Ntrkr1 protein
  • RGD1559469 protein
  • ROR1 protein
  • ROR2 protein
  • ROR3 protein
  • sg protein
  • staggerer protein
  • tmgc26 protein

Protein level used designations for ROR1

tyrosine kinase orphan receptor 1 , tyrosine-protein kinase transmembrane receptor ROR1 , receptor tyrosine kinase-like orphan receptor 1 , tyrosine-protein kinase transmembrane receptor ROR1-like , nuclear receptor ROR-alpha , nuclear receptor RZR-alpha , nuclear receptor subfamily 1 group F member 1 , retinoid-related orphan receptor-alpha , neurotrophic tyrosine kinase, receptor-related 1 , neurotrophic tyrosine kinase, receptor related 1

395179 Gallus gallus
456910 Pan troglodytes
489557 Canis lupus familiaris
700760 Macaca mulatta
783965 Bos taurus
100415610 Callithrix jacchus
100477806 Ailuropoda melanoleuca
100598117 Nomascus leucogenys
19883 Mus musculus
4919 Homo sapiens
26563 Mus musculus
362550 Rattus norvegicus
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