Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Human VEGFC Protein expressed in CHO Cells - ABIN2666942
Cai, Ma, Gu, Zu, Qu, Zheng: Survivin regulates the expression of VEGF-C in lymphatic metastasis of breast cancer. in Diagnostic pathology 2012
Show all 6 references for ABIN2666942
Human VEGFC Protein expressed in Escherichia coli (E. coli) - ABIN413872
Werchau, Toberer, Enk, Dammann, Helmbold: Merkel cell carcinoma induces lymphatic microvessel formation. in Journal of the American Academy of Dermatology 2011
Show all 6 references for ABIN413872
Mouse (Murine) VEGFC Protein expressed in Escherichia coli (E. coli) - ABIN1047898
Fitz, Morris, Towler, Long, Burgess, Greco, Wang, Gassaway, Nickbarg, Kovacic, Ciarletta, Giannotti, Finnerty, Zollner, Beier, Leak, Turner, Wood: Characterization of murine Flt4 ligand/VEGF-C. in Oncogene 1997
Show all 3 references for ABIN1047898
Human VEGFC Protein expressed in Escherichia coli (E. coli) - ABIN1047897
Lee, Gray, Yuan, Luoh, Avraham, Wood: Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4. in Proceedings of the National Academy of Sciences of the United States of America 1996
Show all 2 references for ABIN1047897
Rat (Rattus) VEGFC Protein expressed in Human Cells - ABIN2009156
Mandriota, Pepper: [Lymphangiogenesis and biological activity ov vascular endothelial growth factor-C]. in Journal de la Société de biologie 1999
Human VEGFC Protein expressed in Wheat germ - ABIN1324984
Singh, Tiem, Watkins, Cho, Wang, Olsen, Uehara, Mamalis, Luo, Oakey, Ambati: Soluble vascular endothelial growth factor receptor 3 is essential for corneal alymphaticity. in Blood 2013
data not only reveal a non-canonical function of Mt2 (show MT2 Proteins) in angiogenesis, but also propose Mt2 (show MT2 Proteins) as a novel regulator of vegfc expression.
Vegfc signaling increases mafba (show MAFB Proteins) expression to control downstream transcription
Vegfc is dispensable for facial lymphatic sprouting but not for the complete development of the facial lymphatic network.
In the embryo, phenotypes driven by increased Vegfc are suppressed in the absence of Ccbe1 (show CCBE1 Proteins), and Vegfc-driven sprouting is enhanced by local Ccbe1 (show CCBE1 Proteins) overexpression. Moreover, Vegfc- and Vegfr3 (show FLT4 Proteins)-dependent Erk (show MAPK1 Proteins) signaling is impaired in the absence of Ccbe1 (show CCBE1 Proteins).
Vegfc has an essential role in lymphangiogenesis [review]
The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 (show FLT4 Proteins) signaling in zebrafish.
Vegfc acts in two distinct modes during development: as a paracrine factor secreted from arteries to guide closely associated lymphatic vasculature and as an autocrine factor to drive migratory persistence during angiogenesis.
Rspo1-Wnt-VegfC-Vegfr3 signaling plays a crucial role as an endothelial-autonomous permissive cue for developmental angiogenesis.
Here, we show that vascular endothelial growth factor C (Vegfc), an angiogenic as well as a lymphangiogenic factor, is unexpectedly involved in this process in zebrafish.
The development of lymphatic vessels in zebrafish embyros depends on Vegfc signaling.
VEGF-C and VEGF-C156S genes have roles in the pro-lymphangiogenic growth factor therapy of lymphedema
Transcription of the vascular endothelial growth factor C gene (VEGF-C) and translation of the corresponding protein were significantly up-regulated in swine umbilical vein endothelial cells with classical swine fever virus acute infection.
No difference in bioactivity was detected between porcine relaxin-1 (show RLN1 Proteins) and recombinant human relaxin-2 (show RLN1 Proteins) in either mice or rats.
During progressive ischemia, functional and metabolic benefits of intramyocardial VEGF-C gene transfer were apparent. VEGF-C-induced collateral formation occurred at the site of gene transfer
Our data suggested that IL-6 (show IL6 Proteins) mediates the singnal pathway of JAK (show JAK3 Proteins)-STAT3 (show STAT3 Proteins)-VEGF-C promoting the growth, invasion and lymphangiogenesis in gastric cancer
The most extensively accepted signaling pathways promoting lymphangiogenesis in tumors include the secreted lymphangiogenic proteins: VEGF-C and VEGF-D (show Figf Proteins), and their cognate receptor on lymphatic endothelium VEGF receptor (show FLT1 Proteins)-3 (VEGFR-3 (show FLT4 Proteins)).
the concurrent high expression of VEGF-C and NRP2 (show NELL2 Proteins) is predictive of the unfavorable prognosis in glioblastoma.
VEGF family members may have important roles in myocardial lymphatics in healthy and in cardiac disease.
a significant decrease in miR101 levels, accompanied with an increased expression of vascular endothelial growth factor (VEGF)C in cisplatinresistant SGC7901 gastric cancer cells.
MTA1 (show MTA1 Proteins) is up-regulated in CRC (show CALR Proteins); its expression is inversely associated with lymphatic metastases and the expression of VEGFC, VEGFD (show Figf Proteins) and VEGFR3 (show FLT4 Proteins)
miR (show MLXIP Proteins)-27b, miR (show MLXIP Proteins)-101 and miR (show MLXIP Proteins)-128 inhibit angiogenesis by down-regulating VEGF-C expression in gastric cancers.
VEGF-C/D score correlated neither with peypher lymphatic vessel density (LVD) nor with LVD in the tumor center
study suggests that both VEGF-C and VEGF-D (show Figf Proteins) in tumor cells promote lymph node metastasis
Human lung-resident macrophages express CB1 (show CNR1 Proteins) and CB2 (show CNR2 Proteins) receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors
The authors show that VEGF-C is necessary for perinatal lymphangiogenesis, but required for adult lymphatic vessel maintenance only in the intestine.
MT1-MMP (show MMP14 Proteins) directly cleaves LYVE-1 (show LYVE1 Proteins) on lymphatic endothelial cells to inhibit LYVE-1 (show LYVE1 Proteins)-mediated lymphangiogenic responses and restrains the production of VEGF-C.
HA increases lymphangiogenesis in renal fibrosis model and also stimulates vascular endothelial cell growth factor (show FGF1 Proteins)-C production from macrophages through Toll-like receptor 4 (show TLR4 Proteins)-dependent signal pathway
Results showed that the VEGF-C/VEGFR-3 (show FLT4 Proteins) system underlies the protective effect of ischemic preconditioning against forebrain ischemia in the mouse hippocampus
Vascular endothelial growth factor C/VEGFR-3 (show FLT4 Proteins) signaling modifies HS and CCL21 (show CCL21 Proteins) gradients around lymphatics, regulating lymphocyte migration.
Coronary artery stem development first requires VEGF-C to stimulate vessel growth around the outflow tract.
Data show that the expression of lymphatic vessel endothelial hyaluronan receptor 1 (LYVE 1 (show LYVE1 Proteins)) was similar with vascular endothelial growth factor C (VEGF-C), but its peak appeared 1-2 d later than that of VEGF-C.
reveal the evolutionary conservation of the lymphatic-like phenotype of the Schlemm's canal (SC), implicate VEGF-C and VEGFR-3 (show FLT4 Proteins) as critical regulators of SC lymphangiogenesis
Sinus venosus-derived and endocardial-derived migratory routes unite to form the coronary vasculature, with the former requiring VEGFC - a tissue-specific mediator of blood endothelial development.
suggest that correction of defective lymphatic function with VEGF-C has potential as a therapeutic strategy for inflammatory bowel disease.
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
vascular endothelial growth factor C
, vascular endothelial growth factor c
, FLT4 ligand DHM
, vascular endothelial growth factor-related protein
, flt4 ligand
, vascular endothelial growth factor C isoform 129
, vascular endothelial growth factor C isoform 184