VEGFC Protein (AA 102-227)
Quick Overview for VEGFC Protein (AA 102-227) (ABIN2018451)
Target
See all VEGFC ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 102-227
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Characteristics
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Measured in a cell proliferation assay using HMVEC human microvascular endothelial cells. The ED50 for this effect is < 0.5 μg/mL.
AA 102-227 with an N-terminal Met. -
Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) (Active) protein (His-Avi Tag)
VEGFC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) (Active) protein (Biotin,His-Avi Tag)VEGFC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Vascular Endothelial Growth Factor C (VEGFC) (AA 1-419) protein (GST tag)VEGFC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227) protein (His tag)VEGFC Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227), (full length) protein (GST tag)VEGFC Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant Human Vascular Endothelial Growth Factor C remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Vascular Endothelial Growth Factor C should be stable up to 1 week at 4 °C or up to 3 months at -20 °C.
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Expiry Date
- 6 months
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- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
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Alternative Name
- Vascular Endothelial Growth Factor C (VEGF-C)
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Background
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Vascular endothelial growth factor C (VEGF-C) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis, lymphangiogenesis and endothelial cell growth and survival, and can also affect the permeability of blood vessels. VEGF-C is expressed in various tissues, however it is not produced in peripheral blood lymphocytes. It forms cell surface-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. The structure and function of VEGF-C is similar to those of vascular endothelial growth factor D (VEGF-D).Recombinant human VEGF-C produced in HEK293 cells is a polypeptide chain containing 126 amino acids. A fully biologically active molecule, rhVEGF-C has a molecular mass of 16-19 kDa analyzed by reducing SDS-PAGE.
Synonyms: Flt4 ligand, VRP -
Molecular Weight
- 16-19 kDa, observed by reducing SDS-PAGE.
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UniProt
- P14844
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Pathways
- RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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