VEGFC Protein (AA 102-227)
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- Target See all VEGFC Proteins
- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 102-227
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Origin
- Human
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Source
- HEK-293T Cells
- Characteristics
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Measured in a cell proliferation assay using HMVEC human microvascular endothelial cells. The ED50 for this effect is < 0.5 μg/mL.
AA 102-227 with an N-terminal Met. - Purity
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product VEGFC Protein
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Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) protein (His-Avi Tag)
VEGFC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) protein (His-Avi Tag,Biotin)VEGFC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Vascular Endothelial Growth Factor C (VEGFC) (AA 1-419) protein (GST tag)VEGFC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) protein (His tag)VEGFC Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227) protein (GST tag)VEGFC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227) protein (His tag)Crystallography grade VEGFC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227), (full length) protein (GST tag)VEGFC Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant Human Vascular Endothelial Growth Factor C remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Vascular Endothelial Growth Factor C should be stable up to 1 week at 4 °C or up to 3 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
- Alternative Name
- Vascular Endothelial Growth Factor C (VEGF-C) (VEGFC Products)
- Synonyms
- VEGFC Protein, vegf-c Protein, xvegf-c Protein, Flt4-L Protein, VRP Protein, AW228853 Protein, VEGF-C Protein, vascular endothelial growth factor c Protein, vascular endothelial growth factor C Protein, vascular endothelial growth factor C S homeolog Protein, vegfc Protein, VEGFC Protein, vegfc.S Protein, Vegfc Protein
- Background
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Vascular endothelial growth factor C (VEGF-C) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis, lymphangiogenesis and endothelial cell growth and survival, and can also affect the permeability of blood vessels. VEGF-C is expressed in various tissues, however it is not produced in peripheral blood lymphocytes. It forms cell surface-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. The structure and function of VEGF-C is similar to those of vascular endothelial growth factor D (VEGF-D).Recombinant human VEGF-C produced in HEK293 cells is a polypeptide chain containing 126 amino acids. A fully biologically active molecule, rhVEGF-C has a molecular mass of 16-19 kDa analyzed by reducing SDS-PAGE.
Synonyms: Flt4 ligand, VRP - Molecular Weight
- 16-19 kDa, observed by reducing SDS-PAGE.
- UniProt
- P14844
- Pathways
- RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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