Browse our anti-CHD7 (CHD7) Antibodies

Full name:
anti-Chromodomain Helicase DNA Binding Protein 7 Antibodies (CHD7)
On www.antibodies-online.com are 42 Chromodomain Helicase DNA Binding Protein 7 (CHD7) Antibodies from 11 different suppliers available. A total of 45 CHD7 products are currently listed.
Synonyms:
A730019I05Rik, CHD7, Cycn, Cyn, Dz, Edy, fd19h06, Flo, GENA 47, Gena 52, GENA 60, HH5, IS3, KAL5, Lda, metis, Mt, Obt, si:ch211-197o6.2, Todo, WBE1, Whi, wu:cegs2051, wu:fb37f10, wu:fb39h04, wu:fd19h06
list all antibodies Gene Name GeneID UniProt
CHD7 55636 Q9P2D1
CHD7 320790 A2AJK6
CHD7 312974  

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anti-Human CHD7 Antibodies:

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anti-Rat (Rattus) CHD7 Antibodies:

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Top referenced anti-CHD7 Antibodies

  1. Human Polyclonal CHD7 Primary Antibody for ICC, IF - ABIN4297899 : Colbert, Petrova, Fisher, Pantazides, Madden, Hardy, Warren, Pan, Nagaraju, Liu, Saka, Hall, Shelton, Gandhi, Pauly, Kowalski, Kooby, El-Rayes, Staley, Adsay, Curran, Landry, Maithel, Yu: CHD7 expression predicts survival outcomes in patients with resected pancreatic cancer. in Cancer research 2014 (PubMed)

  2. Human Polyclonal CHD7 Primary Antibody for ELISA, WB - ABIN238550 : Gao, Gordon, Zhang, Browne, Helms, Gillum, Weber, Devroy, Swaney, Dobbs, Morcuende, Sheffield, Lovett, Bowcock, Herring, Wise: CHD7 gene polymorphisms are associated with susceptibility to idiopathic scoliosis. in American journal of human genetics 2007 (PubMed)

More Antibodies against CHD7 Interaction Partners

Xenopus laevis Chromodomain Helicase DNA Binding Protein 7 (CHD7) interaction partners

  1. evolutionarily conserved role for CHD7 in orchestrating neural crest gene expression programs

Zebrafish Chromodomain Helicase DNA Binding Protein 7 (CHD7) interaction partners

  1. Our zebrafish CHARGE model thus reveals important regulatory roles for Chd7 at multiple points of neural crest development viz., migration, fate choice and differentiation and we suggest that sox10 (show SOX10 Antibodies) deregulation is an important driver of the neural crest-derived aspects of Chd7 dependent CHARGE syndrome.

  2. knockdown of the jumonji (show JARID2 Antibodies) domain-containing histone demethylase (show MBD2 Antibodies) fbxl10 (show KDM2B Antibodies)/kdm2bb, a repressor of ribosomal RNA genes, rescues cell proliferation and cartilage defects in chd7 morphant embryos and can lead to complete rescue of the CHARGE syndrome phenotype.

  3. Chd7 is required for the organization of the neural retina in zebrafish.

  4. Data show that Chd7 deficiency leads to asymmetric segmentation of the presomitic mesoderm (PSM (show SH2B1 Antibodies)), and results in the loss of asymmetric expression of spaw in the lateral plate mesoderm, which is consistent with more general laterality defects.

Human Chromodomain Helicase DNA Binding Protein 7 (CHD7) interaction partners

  1. Data suggest protein levels of kalirin (show KALRN Antibodies) and CHD7 in circulating extracellular vesicles (EVs) as endothelial dysfunction markers to monitor vascular condition in hypertensive patients with albuminuria.

  2. Data suggest that CHD6 (show CHD6 Antibodies) and CHD7 both bind with high affinity to short linker DNA, whereas CHD8 (show CHD8 Antibodies) requires longer DNA for binding; thus, CHD8 (show CHD8 Antibodies) slides nucleosomes into positions with more flanking linker DNA than CHD7; CHD6 (show CHD6 Antibodies) disrupts nucleosomes in a distinct non-sliding manner.

  3. Our findings provide evidence that CHARGE and Kabuki syndromes result from dysregulatrion of CHD7 and KMT2D (show MLL2 Antibodies) genes involved embryonal development that are expressed in a tissue-specific manner.

  4. De novo missense variant in CHD7 identified in a family presenting with musculoskeletal abnormalities as the main manifestation of CHD7-related disease, representing a new phenotype.

  5. Our zebrafish CHARGE model thus reveals important regulatory roles for Chd7 at multiple points of neural crest development viz., migration, fate choice and differentiation and we suggest that sox10 (show SOX10 Antibodies) deregulation is an important driver of the neural crest-derived aspects of Chd7 dependent CHARGE syndrome.

  6. This study established a new epigenetic regulation of mesenchymal stem cell (MSC (show MSC Antibodies)) osteogenic differentiation and provided a potential target for controlling MSC (show MSC Antibodies) osteogenesis.

  7. the case of a girl with a novel heterozygous deletion in exon 15 of the CHD7 gene and combined agenesis of uterus and ovaries, besides gonadotropin deficiency, thus expanding the geno-phenotype of CHARGE syndrome.

  8. We report here another sporadic case with mild CHARGE syndrome, with heart defect (show Vcan Antibodies), sensorineural deafness and hypoplastic semi-circular canals. It should be emphasized that patients should not be rejected for CHD7 analysis if they do not fulfill criteria for atypical or typical CHARGE as there is a high intra- and inter-familial variability

  9. Pathogenic CHD7 variants are associated with CHARGE syndrome.

  10. Two mutations of CHD7 were identified including a novel splice-site mutation (c.2443-2A>G) and a previously known frameshift mutation (c.2504_2508delATCTT).

Mouse (Murine) Chromodomain Helicase DNA Binding Protein 7 (CHD7) interaction partners

  1. CHD7 (show CHD3 Antibodies) is necessary for maintaining an open, accessible chromatin state at the Reln (show RELN Antibodies) locus. Taken together, this study shows that Reln (show RELN Antibodies) gene expression is regulated by chromatin remodeling, identifies CHD7 (show CHD3 Antibodies) as a previously unrecognized upstream regulator of Reln (show RELN Antibodies), and provides direct in vivo evidence that a mammalian CHD (show CHRD Antibodies) protein can control brain development

  2. Chd7 (show CHD3 Antibodies) coordinates with Sox10 (show SOX10 Antibodies) to regulate the initiation of myelinogenesis and acts as a molecular nexus of regulatory networks that account for the development of a seemingly diverse array of lineages, including oligodendrocytes and osteoblasts, pointing to previously uncharacterized Chd7 (show CHD3 Antibodies) functions.

  3. Chd7 (show CHD3 Antibodies) mutant mice are models for determining the molecular etiology of ocular defects in CHARGE syndrome.

  4. This work reveals the importance of CHD7 (show CHD3 Antibodies) in the cardiogenic mesoderm for multiple processes during cardiovascular development.

  5. Findings directly link CHD7 (show CHD3 Antibodies) to pathways involved in NSC quiescence and identify the first chromatin-remodeling factor (show ASH1L Antibodies) with a role in NSC quiescence and maintenance.

  6. Conditional deletion of Chd7 (show CHD3 Antibodies) in ectodermal and endodermal derivatives or migrating neural crest cells results in varied and severe craniofacial defects.

  7. CHD7 (show CHD3 Antibodies) gene mutation is associated with CHARGE syndrome.

  8. Findings demonstrate critical, cooperative roles for Retinoic Acid (RA) and CHD7 (show CHD3 Antibodies) in subventricular zone neural stem cell function and inner ear development, suggesting that altered RA signaling may be an effective method for treating Chd7 (show CHD3 Antibodies) deficiency.

  9. Chd7 (show CHD3 Antibodies) may have critical selector gene functions during inner ear morphogenesis.

  10. CHD7 (show CHD3 Antibodies) may directly regulate Bmp4 (show BMP4 Antibodies) expression by binding with an enhancer element downstream of the Bmp4 (show BMP4 Antibodies) locus.

CHD7 Antigen Profile

Antigen Summary

This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome.

Alternative names and synonyms associated with CHD7

  • chromodomain helicase DNA binding protein 7 (chd7) antibody
  • chromodomain helicase DNA binding protein 7 (CHD7) antibody
  • chromodomain helicase DNA binding protein 7 (Chd7) antibody
  • A730019I05Rik antibody
  • CHD7 antibody
  • Cycn antibody
  • Cyn antibody
  • Dz antibody
  • Edy antibody
  • fd19h06 antibody
  • Flo antibody
  • GENA 47 antibody
  • Gena 52 antibody
  • GENA 60 antibody
  • HH5 antibody
  • IS3 antibody
  • KAL5 antibody
  • Lda antibody
  • metis antibody
  • Mt antibody
  • Obt antibody
  • si:ch211-197o6.2 antibody
  • Todo antibody
  • WBE1 antibody
  • Whi antibody
  • wu:cegs2051 antibody
  • wu:fb37f10 antibody
  • wu:fb39h04 antibody
  • wu:fd19h06 antibody

Protein level used designations for CHD7

chromodomain helicase DNA binding protein 7 , fb37f10 , fb39h04 , chromodomain-helicase-DNA-binding protein 7-like , ATP-dependent helicase CHD7 , chromodomain helicase DNA binding protein 7 isoform CRA_e , chromodomain-helicase-DNA-binding protein 7 , CHD-7 , chromodomain helicase DNA-binding protein 7

GENE ID SPECIES
443577 Xenopus laevis
464198 Pan troglodytes
486968 Canis lupus familiaris
533175 Bos taurus
569471 Danio rerio
100339550 Oryctolagus cuniculus
100379668 Xenopus (Silurana) tropicalis
100461260 Pongo abelii
100479808 Ailuropoda melanoleuca
100580875 Nomascus leucogenys
55636 Homo sapiens
320790 Mus musculus
312974 Rattus norvegicus
421140 Gallus gallus
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