CHD7 antibody (AA 2025-2075)

Catalog No. ABIN7451215

Product Details anti-CHD7 Antibody

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Binding Specificity: AA 2025-2075

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD7 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-CHD7 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 2025 and 2075

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-CHD7 antibody ABIN7453314.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CHD7

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Alternative Name: CHD7 (CHD7 Products)

Synonyms: CHD7 antibody, fd19h06 antibody, si:ch211-197o6.2 antibody, wu:cegs2051 antibody, wu:fb37f10 antibody, wu:fb39h04 antibody, wu:fd19h06 antibody, HH5 antibody, IS3 antibody, KAL5 antibody, A730019I05Rik antibody, Cycn antibody, Cyn antibody, Dz antibody, Edy antibody, Flo antibody, GENA 47 antibody, GENA 60 antibody, Gena 52 antibody, Lda antibody, Mt antibody, Obt antibody, Todo antibody, WBE1 antibody, Whi antibody, metis antibody, chromodomain helicase DNA binding protein 7 L homeolog antibody, chromodomain helicase DNA binding protein 7 antibody, chd7.L antibody, CHD7 antibody, chd7 antibody, Chd7 antibody

Background: Background: CHD7 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD7 is implicated to play a role in development. Mutations in CHD7 are associated with CHARGE syndrome, a multi-symptom syndrome characterized by congenital anomalies and malformations of the heart, inner ear, retina, and palate.

Gene ID: 55636

NCBI Accession: NP_060250

UniProt: Q9P2D1

Pathways: Sensory Perception of Sound, Chromatin Binding