CHD7 antibody (AA 2025-2075)

Catalog No. ABIN7451215

This Rabbit Polyclonal antibody specifically detects CHD7 in IP. It exhibits reactivity toward Human.

Quick Overview for CHD7 antibody (AA 2025-2075) (ABIN7451215)

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD7 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-CHD7 Antibody

Binding Specificity: AA 2025-2075

Purpose: Rabbit anti-CHD7 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 2025 and 2075

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-CHD7 antibody ABIN7453314.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CHD7

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Alternative Name: CHD7

Background: Background: CHD7 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD7 is implicated to play a role in development. Mutations in CHD7 are associated with CHARGE syndrome, a multi-symptom syndrome characterized by congenital anomalies and malformations of the heart, inner ear, retina, and palate.

Gene ID: 55636

NCBI Accession: NP_060250

UniProt: Q9P2D1

Pathways: Sensory Perception of Sound, Chromatin Binding