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Gap Junction Protein, beta 3, 31kDa Proteins (GJB3)
On are 14 Gap Junction Protein, beta 3, 31kDa (GJB3) Proteins from 5 different suppliers available. Additionally we are shipping Gap Junction Protein, beta 3, 31kDa Antibodies (79) and Gap Junction Protein, beta 3, 31kDa Kits (20) and many more products for this protein. A total of 117 Gap Junction Protein, beta 3, 31kDa products are currently listed.
Cnx31, connexin-31, CX31, D4Wsu144e, DFNA2, DFNA2B, EKV, Gjb-3, gjb3b
list all proteins Gene Name GeneID UniProt
GJB3 14620 P28231
GJB3 29585 P25305
GJB3 2707 O75712

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More Proteins for Gap Junction Protein, beta 3, 31kDa Interaction Partners

Mouse (Murine) Gap Junction Protein, beta 3, 31kDa (GJB3) interaction partners

  1. Prostaglandin E stimulates Connexin isoforms via GSK-3beta/beta-catenin (show CTNNB1 Proteins) via EP2-receptor-dependent cAMP/PKA and PI3K/Akt (show AKT1 Proteins) in mouse embryonic stem cells.

  2. Connexin 31-deficient trophoblast stem cells revealed a shift in giant cell differentiation from Prl3d1 expressing parietal giant cells to Ctsq, Prl3b1, and Prl2c2-positive giant cells.

  3. Expression profile of the Gjb3 in the developing mouse cochlea

  4. Mutant cx31 showed reduced phosphorylation levels compared to Cx31 wild type, indicating a pivotal role of serine residue 266 for Cx31 phosphorylation, but didn't interfere with correct intracellular trafficking of gap junction proteins.

  5. During trophoblast cell lineage differentiation, the Cx31 gap junction channel is involved in maintaining the proliferative diploid trophoblast cell population.

  6. Cx31/Cx43 (show GJA1 Proteins) double-deficient mice exhibit the known phenotypes of the single-knockout strains but no combined effects

  7. Cx31 and Cx43 (show GJA1 Proteins) proteins functionally interact, possibly by forming heteromeric channels in the epidermis.

Human Gap Junction Protein, beta 3, 31kDa (GJB3) interaction partners

  1. The results of the present study indicated that combined heterozygous mutations of the SLC264 and GJB3 genes may result in severe hearing loss. These results contribute to the understanding of clinical phenotype of deaf patients carrying combined mutations in the SLC26A4 (show SLC26A4 Proteins) and GJB3 genes.

  2. study suggests that Connexin-31 mutant proteins are un/misfolded to cause erythrokeratodermia variabilis likely via an AP-1 (show FOSB Proteins)-mediated mechanism and identifies a small molecule with therapeutic potential of the disease

  3. identified dominant pathogenic missense mutation in the M4 transmembrane domain of GJB3; mutation led to the erythrokeratodermia variabilis (EKV) phenotype in the patient's family; results, combined with literature review, suggest dominant missense mutations outside the E2 domain in GJB3 are associated with EKV, and those within the E2 domain cause ADNSHL

  4. Mutations in 12S rRNA, SLC26A4 (show SLC26A4 Proteins), GJB2 (show GJB2 Proteins) and GJB3 are highly associated with deafness.

  5. The CX31 V174M mutant may have an effect on the formation and function of the gap junction, in nonsyndromic hearing loss.

  6. In this study, we found no mutations of GJB3 in two Progressive symmetrical erythrokeratoderma families.

  7. We report a missense mutation p.G45E in the GJB3 gene, which was responsible for Erythrokeratodermia variabilis in a Chinese family.

  8. GJB3 and GJB6 (show GJB6 Proteins) genetic variants are associated with the pathogenicity of nonsyndromic sensorineural hearing loss.

  9. Mutation analysis of GJB3 and GJB4 (show GJB4 Proteins) in Chinese patients with erythrokeratodermia variabilis.

  10. Pathogenic connexin-31 forms constitutively active hemichannels to promote necrotic cell death

Gap Junction Protein, beta 3, 31kDa (GJB3) Protein Profile

Protein Summary

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Alternative names and synonyms associated with Gap Junction Protein, beta 3, 31kDa (GJB3)

  • gap junction protein, beta 3, 31kDa (gjb3)
  • gap junction protein, beta 3, 31kDa (GJB3)
  • gap junction protein, beta 3 (Gjb3)
  • gap junction protein, beta 6, 30kDa (GJB6)
  • Cnx31 protein
  • connexin-31 protein
  • CX31 protein
  • D4Wsu144e protein
  • DFNA2 protein
  • DFNA2B protein
  • EKV protein
  • Gjb-3 protein
  • gjb3b protein

Protein level used designations for GJB3

connexin 31 b , connexin 31 , gap junction protein, beta 3 b , gap junction protein, beta 3, 31kDa , connexin-31 , gap junction beta-3 protein , gap junction membrane channel protein beta 3 , cx31 , gap junction beta 3 , gap junction beta-6 protein , gap junction protein, beta 6 (connexin 30)

443903 Xenopus laevis
482486 Canis lupus familiaris
100038103 Xenopus (Silurana) tropicalis
14620 Mus musculus
29585 Rattus norvegicus
2707 Homo sapiens
539935 Bos taurus
395771 Gallus gallus
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