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Complement C4 Proteins

(Complement 4 (C4))
This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
Complement 4 (C4) (Active) protein (ABIN4888419)

C4 Origin: Human Host: Human Native > 99 % pure Active

Complement 4 (C4) (AA 126-366) protein (His tag) (ABIN7080579)

C4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % Imm, PC, SDS, WB

Complement 4 (C4) (AA 975-1336) protein (His tag) (ABIN7080583)

C4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % Imm, PC, SDS, WB

Complement C4 Proteins by Origin

Find Complement C4 Proteins for a variety of species such as anti-Human Complement C4, anti-Mouse Complement C4, anti-Rat Complement C4. The species listed below are among those available. Click on a link to go to the corresponding products.

Complement C4 Proteins by Source

Find Complement C4 Proteins with a specific Source. The Source listed below are among those available. Click on a link to go to the corresponding products.

Complement C4 Proteins by Protein Type

Find Complement C4 Proteins with a specific Protein Type. The Protein Type listed below are among those available. Click on a link to go to the corresponding products.

Complement C4 Proteins by Application

Find Complement C4 Proteins validated for a specific application such as Imm, PC, SDS, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Complement C4 Proteins by Biological Activity

Find Complement C4 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Complement C4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7080582
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7080580
Quantity 50 μg
Datasheet Datasheet
Reactivity Chicken
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7080581
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Human
Validations
Cat. No. ABIN1880329
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Human
Validations
Cat. No. ABIN5852137
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1666700
Quantity 1 mg
Datasheet Datasheet

Aliases for Complement C4 Proteins

complement C4B (Chido blood group) (C4B) Proteins
complement C4A (Rodgers blood group) (C4A) Proteins
complement component 4A (Rodgers blood group) (C4a) Proteins
complement 4 (C4) Proteins
complement component 4A (C4A) Proteins
complement component 4B (Chido blood group) (C4b) Proteins
C4 Proteins
C4-1 Proteins
C4-2 Proteins
C4A2 Proteins
C4A3 Proteins
C4A4 Proteins
C4A6 Proteins
C4AD Proteins
C4b Proteins
C4B1 Proteins
C4B2 Proteins
C4B3 Proteins
C4B5 Proteins
C4B12 Proteins
C4BD Proteins
C4B_2 Proteins
C4F Proteins
C4S Proteins
CH Proteins
CO4 Proteins
CPAMD2 Proteins
CPAMD3 Proteins
RG Proteins
Slp Proteins
Ss Proteins
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