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Browse our anti-TECTA (TECTA) Antibodies

Full name:
anti-Tectorin alpha Antibodies (TECTA)
On www.antibodies-online.com are 7 Tectorin alpha (TECTA) Antibodies from 6 different suppliers available. Additionally we are shipping and many more products for this protein. A total of 8 TECTA products are currently listed.
Synonyms:
DFNA8, DFNA12, DFNB21, Tctna
list all antibodies Gene Name GeneID UniProt
TECTA 7007 O75443
Anti-Mouse TECTA TECTA 21683 O08523
Anti-Rat TECTA TECTA 300653  

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anti-Human TECTA Antibodies:

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Human Tectorin alpha (TECTA) interaction partners

  1. Up to now, merely 7 loci have been linked to mid-frequency hearing loss. Only four genetic mid-frequency deafness genes, namely, DFNA10 (EYA4 (show EYA4 Antibodies)), DFNA8/12 (TECTA), DFNA13 (COL11A2 (show COL11A2 Antibodies)), DFNA44 (CCDC50 (show CCDC50 Antibodies)), have been reported to date. [review]

  2. A novel homozygous variant (c.734G > A) was found in exon 5 of the TECTA gene in one family leading to a nonsense mutation causing autosomal recessive nonsyndromic hearing loss.

  3. To our knowledge, this is the first reported TECTA mutation leading to the DFNB21 form of hearing impairment among Maghrebian individuals suffering from congenital hearing impairment

  4. the present report suggest that the association of RWDD3 (show RWDD3 Antibodies) and TECTA with paclitaxel-induced peripheral neuropathy may have been a false positive signal

  5. Whole-exome sequencing identifies a novel genotype-phenotype correlation in the entactin (show NID1 Antibodies) domain of the known deafness gene TECTA.

  6. Identified the c.211delC mutation in the KCNQ4 (show KCNQ4 Antibodies) gene and the c.2967C>A (p.H989Q) mutation in the TECTA gene to be associated with high-frequency sensorineural hearing loss in a Japanese family.

  7. A rare novel mutation in TECTA causes autosomal dominant nonsyndromic hearing loss in a Mongolian family.

  8. Data indicate that sequencing of candidate gene TECTA (alpha-tectorin) revealed a heterozygous c.5945C>A substitution in exon 19, causing amino acid substitution of Ala to Asp (show ASIP Antibodies) at a conservative position 1982.

  9. this study failed to replicate a GWAS reporting an association between the 2 SNPs rs2296308 in RWDD3 (show RWDD3 Antibodies) and rs1829 in the intron of TECTA and time to neuropathy in ovarian cancer patients treated with paclitaxel

  10. we have reported the prevalence of TECTA mutations in Japanese autosomal dominant nonsyndromic hearing loss (ADNSHL) patients detected by genetic screening, and confirmed the genotype-phenotype correlations.

Mouse (Murine) Tectorin alpha (TECTA) interaction partners

  1. Alpha-tectorin and beta-tectorin (show TECTB Antibodies) crosslink type II collagen (show COL2A1 Antibodies) fibrils and connect the tectorial membrane to the spiral limbus.

  2. Tecta mutant mice all exhibit an enhanced tendency to have audiogenic seizures in response to white noise stimuli.

  3. CEACAM16 (show CEACAM16 Antibodies) can probably form higher order structures with other tectorial membrane proteins such as alpha-tectorin and beta-tectorin (show TECTB Antibodies) and influences the physical properties of the tectorial membrane

  4. The morphology and mechanical properties of wild-type, heterozygous, and homozygous Tecta tecta membrane, were analysed.

  5. In Tecta(Y)(1870C/+) mice, the tectorin content of the tectorial membrane was reduced, as was the content of glycoconjugates reacting with the lectin wheat germ agglutinin.

  6. The Tecta (A349D/A349D) mouse reveals that missense mutations in Tecta can be recessive and lead to tectorial membrane detachment

TECTA Antigen Profile

Antigen Summary

The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness.

Alternative names and synonyms associated with TECTA

  • tectorin alpha (TECTA) antibody
  • tectorin alpha (Tecta) antibody
  • DFNA8 antibody
  • DFNA12 antibody
  • DFNB21 antibody
  • Tctna antibody

Protein level used designations for anti-Tectorin alpha (TECTA) Antibodies

tectorin alpha , alpha-tectorin-like , alpha-tectorin , [a]-tectorin , alpha tectorin

GENE ID SPECIES
451622 Pan troglodytes
489357 Canis lupus familiaris
712586 Macaca mulatta
100459434 Pongo abelii
100604140 Nomascus leucogenys
7007 Homo sapiens
21683 Mus musculus
300653 Rattus norvegicus
395686 Gallus gallus
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