Browse our TMPRSS3 Proteins (TMPRSS3)

Full name:
Transmembrane Protease, Serine 3 Proteins (TMPRSS3)
On are 4 Transmembrane Protease, Serine 3 (TMPRSS3) Proteins from 1 different suppliers available. Additionally we are shipping TMPRSS3 Antibodies (71) and TMPRSS3 Kits (2) and many more products for this protein. A total of 85 TMPRSS3 products are currently listed.
list all proteins Gene Name GeneID UniProt
TMPRSS3 64699 P57727
TMPRSS3 140765 Q8K1T0
Rat TMPRSS3 TMPRSS3 309665  

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TMPRSS3 Proteins (TMPRSS3) by Origin

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Human Transmembrane Protease, Serine 3 (TMPRSS3) interaction partners

  1. In conclusion, TMPRSS3 (show TMPRSS4 Proteins) and TNFRSF11B (show TNFRSF11B Proteins) may have potential prognostic value to be used as tumor biomarkers in breast cancer patients.

  2. different combinations of TMPRSS3 (show TMPRSS4 Proteins) mutations led to different hearing impairment phenotypes (DFNB8/DFNB10) in the Chinese family.

  3. TMPRSS3 (show TMPRSS4 Proteins) mutations seem to be an important cause of autosomal recessive nonsyndromic hearing loss in Slovenia resulting in rather uniform phenotype with profound congenital hearing loss.

  4. Study demonstrated that TMPRSS3 contributes to ovarian cancer cell proliferation, invasion and metastasis, probably via activation of the ERK1/2 signaling pathway.

  5. TMPRSS3 (show TMPRSS4 Proteins) expression is an independent prognostic factor for breast cancer patients. Bioinformatic analysis of potential TMPRSS3 (show TMPRSS4 Proteins) binding proteins revealed that TMPRSS3 (show TMPRSS4 Proteins) could be a key regulator of cancer pathways.

  6. Low expression levels of hepsin (show HPN Proteins) and TMPRSS3 (show TMPRSS4 Proteins) are associated with poor breast cancer survival

  7. Single nucleotide polymorphisms in TMPRSS3 (show TMPRSS4 Proteins) (rs3814903 and rs11203200) are significantly associated with breast cancer risk.

  8. homozygous mutation TMPRSS3 (show TMPRSS4 Proteins): c.535G>A causes prelingual hearing loss in this Tibetan family

  9. The prevalence of TMPRSS3 (show TMPRSS4 Proteins) mutations among Korean postlingual hearing loss is 8.3 %. The p.A306T variant of TMPRSS3 (show TMPRSS4 Proteins) is the common founder allele in Koreans. A novel variant, p.T248M of TMPRSS3 (show TMPRSS4 Proteins), was predicted to have milder pathogenicity.

  10. Description of the spectrum of mutations in TMPRSS3 (show TMPRSS4 Proteins) in 374 families with autosomal recessive, non-syndromic hearing loss from India.

Mouse (Murine) Transmembrane Protease, Serine 3 (TMPRSS3) interaction partners

  1. miR (show MLXIP Proteins)-204 has a role in suppressing cochlear spiral ganglion neuron survival in vitro by targeting TMPRSS3

  2. Lack of Tmprss3 leads to a decrease in Kcnma1 (show KCNMA1 Proteins) potassium channels expression in cochlear inner hair cells.

  3. The distribution of TMPRSS3 was observed in many regions of the mouse cochlea, but mainly in the spiral ganglion neurons.

  4. Tmprss3 acts as a permissive factor for cochlear hair cells survival and activation at the onset of hearing and is required for saccular hair cell survival

TMPRSS3 Protein Profile

Protein Summary

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with TMPRSS3

  • transmembrane protease, serine 3 (TMPRSS3)
  • transmembrane protease, serine 3 (Tmprss3)
  • DFNB8 protein
  • DFNB10 protein
  • DKFZp469L1528 protein
  • ECHOS1 protein
  • TADG12 protein
  • TMPRSS3 protein

Protein level used designations for TMPRSS3

transmembrane protease, serine 3 , transmembrane protease serine 3-like , serine protease TADG-12 , transmembrane protease serine 3 , tumor-associated differentially-expressed gene 12 protein , transmembrane proteinase serine 3

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610987 Canis lupus familiaris
714500 Macaca mulatta
100023782 Monodelphis domestica
100057972 Equus caballus
100080632 Ornithorhynchus anatinus
100171839 Pongo abelii
100410672 Callithrix jacchus
100469939 Ailuropoda melanoleuca
64699 Homo sapiens
140765 Mus musculus
309665 Rattus norvegicus
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