You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our CYP1A1 Proteins (CYP1A1)

Full name:
Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 Proteins (CYP1A1)
On are 10 Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) Proteins from 6 different suppliers available. Additionally we are shipping CYP1A1 Antibodies (132) and CYP1A1 Kits (31) and many more products for this protein. A total of 184 CYP1A1 products are currently listed.
AHH, AHRR, CP11, CYP1, CYP1A1, Cyp1a2, Cyp45c, Cypc45c, CYPIA1, P-450MC, P1-450, P450-1, P450-C, P450DX
list all proteins Gene Name GeneID UniProt
CYP1A1 1543 P04798
CYP1A1 24296 P00185
CYP1A1 13076 P00184

Show all synonyms

CYP1A1 Proteins (CYP1A1) by Origin

Select your origin of interest

More Proteins for CYP1A1 Interaction Partners

Pig (Porcine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. Significant CYP1A1 expression increases over control animals was observed in ileum tissue in swine exposed to a single dose of 10 mgkg-bw-1 PAHs

  2. There was no association between CYP1A1 C genotype and survival in the overall study population

  3. The effect of human chorionic gonadotropin on the activities of cytochrome P-450 CYP1A1, cytochrome P-450 CYP2B1 and methoxyresorufin O-demethylase (MROD) was studied in intact male pigs of 2 breeds.[CYP2B1; MROD]

  4. This study demonstrated for the first time that the serum testosterone level is one of the physiological factors which regulate constitutive expression of hepatic CYP1A1 and CYP1A2 (show CYP1A2 Proteins) in pigs.

  5. The findings demonstrate a gender-related difference in the constitutive expression of hepatic CYP1A1 in Meishan pigs and further indicate that testosterone down-regulates the constitutive gene expression of the enzyme.

  6. Distinct subtypes of urinary bladder epithelial cells with inducible and non-inducible cytochrome P-450 CYP1A1 are reported.

  7. Effect of beta-napthoflavone on AHR (show AHR Proteins)-related gene, CYP1A1, in the pig is reported.

Human Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. Our results showed that 3 single nucleotide polymorphisms of ACE rs4340, IL-6 rs1800795, and NOS3 rs1799983 were significantly associated with the risks of mycoplasma pneumoniae pneumonia (MPP), while no differences were observed in genotype frequencies of GSTM1 and CYP1A1. The combinations of ACE/NOS3/CYP1A1 and ACE /NOS3 contribute to the genetic susceptibility of MPP in Chinese children.

  2. the CYP1A1 (rs4646422) polymorphism might be involved in gastric carcinogenesis among the Japanese population.

  3. Report quinone-mediated induction of cytochrome P450 1A1 in HepG2 cells through increased interaction of aryl hydrocarbon receptor (show AHR Proteins) with aryl hydrocarbon receptor nuclear translocator (show ARNT Proteins).

  4. Polymorphism in the CYP1A1 gene is an important risk modifier for lung cancer.

  5. The CYP1A1 Gene of rs4646903 minor alleles and interaction between rs4646903 and rs1048943 were associated with increased cervical cancer risk.

  6. RvD1 down-regulates cytochrome P450 (CYP1A1) and prostaglandin synthase 2 (PTGS2 (show PTGS2 Proteins)) gene expression.

  7. CYP1A1 gene polymorphisms and psychological distress act independently but do not interact with each other in pathogenesis of male infertility.

  8. This meta-analysis suggested that CYP1A1 Ile462Val polymorphism was associated with an increased risk of endometriosis, particularly in Asians. CYP1A1 MspI polymorphism may not be associated with endometriosis risk, but GSTM1 (show GSTM1 Proteins) and CYP1A1 MspI polymorphism may have a joint effect on endometriosis risk

  9. The analysis results showed that the following polymorphisms were correlated with susceptibility to lung cancer: rs4646903 in CYP1A1 (P < 0.001), rs1048943 in CYP1A1 (P < 0.001), rs1695 in GSTP1 (show GSTP1 Proteins) (P < 0.05), rs13181 in ERCC2 (show ERCC2 Proteins) (P < 0.001), and rs25487 in XRCC1 (show XRCC1 Proteins) (P < 0.05); no such correlation existed in rs861539 in XRCC3 (show XRCC3 Proteins) (P > 0.05).

  10. polymorphisms of CYP1A1 gene were not associated with uterine leiomyoma susceptibility, however, the combination of the TT/AG genotypes and TG haplotype could increase risk

Mouse (Murine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. Taken together, CAPE decreases 3-MC-mediated CYP1A1 expression, and this inhibitory response is associated with inhibition of AhR (show AHR Proteins) and HIF-1alpha (show HIF1A Proteins) induction.

  2. Our results support the hypothesis that CYP1A1 protects against hyperoxic lung injury by decreasing oxidative stress.

  3. CYP1A1 contributes to nitric oxide bioavailability and blood pressure regulation mediated by dietary omega-3 polyunsaturated fatty acids.

  4. Aryl hydrocarbon receptor (show AHR Proteins) mediated induction of hepatic CYP1A1/1A2 is dependent on the presence of ctnnb1 (show CTNNB1 Proteins).

  5. Suggest that CYP1A induction by coplanar polychlorinated/brominated biphenyls depends on AhR (show AHR Proteins) transcriptional activity and not on AhR (show AHR Proteins) expression.

  6. Identify hepatic proteins necessary for the AHR (show AHR Proteins)-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  7. In livers of HRN mice Cyp1a1, cytochrome b5 (show CYB5A Proteins) and mEH (show EPHX1 Proteins) can effectively activate BaP (show PHB2 Proteins) to DNA binding species, even in the presence of very low amounts of P450 (show POR Proteins) oxidoreductase (show HSD17B6 Proteins).

  8. Reactive oxygen species production contributes to benzo[a]pyrene (BaP (show PHB2 Proteins))-exacerbated atherosclerosis and CYP1A1 plays a protective role against oral BaP (show PHB2 Proteins) toxicity in aorta

  9. harmine and harmaline are promising candidate to inhibit TCDD-mediated induction of Cyp1a1 in mice hepatic and extrahepatic tissues

  10. Regular consumption of green and white tea exerted protection against benzo(a)pyrene induced toxicity as it modulates the CYP1B1 (show CYP1B1 Proteins), CYP1A1 enzymes, resulting in reduction of BaPDE-DNA adducts formation.

Rabbit Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. CYP1A1 and CYP1A2 (show CYP1A2 Proteins) localization into different lipid microdomains is governed by their N-terminal and internal protein regions

CYP1A1 Protein Profile

Protein Summary

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

Alternative names and synonyms associated with CYP1A1

  • cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1)
  • cytochrome P450 1A1 (CYPIA1)
  • cytochrome P450 1A1 (CpipJ_CPIJ010542)
  • cytochrome P450 1A1 (cyp1a1)
  • cytochrome P450 1A1 (CYP1A1)
  • cytochrome P450, family 1, subfamily a, polypeptide 1 (Cyp1a1)
  • cytochrome P4501A1 (CYP1A1)
  • polycyclic hydrocarbon-inducible cytochrome P450c (LOC100328613)
  • AHH protein
  • AHRR protein
  • CP11 protein
  • CYP1 protein
  • CYP1A1 protein
  • Cyp1a2 protein
  • Cyp45c protein
  • Cypc45c protein
  • CYPIA1 protein
  • P-450MC protein
  • P1-450 protein
  • P450-1 protein
  • P450-C protein
  • P450DX protein

Protein level used designations for CYP1A1

cytochrome P450 1A1 , CYPIA1 , cytochrome P450 CYP1A1 , aryl hydrocarbon hydroxylase , cytochrome P1-450, dioxin-inducible , cytochrome P450 form 6 , cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 , cytochrome P450-C , cytochrome P450-P1 , flavoprotein-linked monooxygenase , xenobiotic monooxygenase , P450MT2 , P450form6 , cytochrome P1-450 , cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c) , cytochrome P450, 1a1 , cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c) , cytochrome P450MT2 , dioxin-inducible , microsomal monooxygenase , aromatic compound inducible , cytochrome P450 family 1 subfamily a polypeptide 2 , cytochrome P450 subfamily I, polypeptide 1 , cytochrome P450, 1a1, aromatic compound inducible , P-450 PHPAH1 , P450 LM6 , P450 isozyme 6 , cytochrome P-450 PHPAH1 , cytochrome P450 LM6 , cytochrome P450 isozyme 6

678694 Macaca mulatta
704920 Macaca mulatta
6043063 Culex quinquefasciatus
100020715 Monodelphis domestica
100062285 Equus caballus
100145341 Xenopus (Silurana) tropicalis
403103 Sus scrofa
554347 Felis catus
1543 Homo sapiens
24296 Rattus norvegicus
13076 Mus musculus
100686778 Canis lupus familiaris
100135512 Cavia porcellus
100170113 Ovis aries
100328613 Oryctolagus cuniculus
Selected quality suppliers for CYP1A1 Proteins (CYP1A1)
Did you look for something else?