CYP1A1 Products
(Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
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This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008].
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Featured CYP1A1 Categories
CYP1A1 Antibodies
High quality antibodies with extensive validation data.
CYP1A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP1A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP1A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7441016
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (8)
Cat. No.
ABIN3023076
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF
Validations
- (5)
Cat. No.
ABIN870663
Quantity
100 μg
Datasheet
Datasheet
Recommended CYP1A1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6955227
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966222
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966223
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP1A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350935
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rhesus Monkey
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407748
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407745
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CYP1A1 products
: "Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[a]Pyrene Metabolite Profile and Its Distribution in 3D Skin." in: mBio, Vol. 12, Issue 5, pp. e0122321, (2022) (PubMed).: "Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 8, pp. 1168-1182, (2019) (PubMed).
: "Biochemical responses of Gammarus pulex to malachite green solutions decolorized by Coriolus versicolor as a biosorbent under batch adsorption conditions optimized with response surface methodology." in: Ecotoxicology and environmental safety, Vol. 156, pp. 41-47, (2018) (PubMed).
: "Cytochrome P450 1A1 (CYP1A1) Catalyzes Lipid Peroxidation of Oleic Acid-Induced HepG2 Cells." in: Biochemistry. Biokhimii͡a, Vol. 83, Issue 5, pp. 595-602, (2018) (PubMed).
: "Resveratrol and its methoxy derivatives modulate the expression of estrogen metabolism enzymes in breast epithelial cells by AhR down-regulation." in: Molecular and cellular biochemistry, Vol. 425, Issue 1-2, pp. 169-179, (2017) (PubMed).
: "Phenethyl isothiocyanate and indole-3-carbinol from cruciferous vegetables, but not furanocoumarins from apiaceous vegetables, reduced PhIP-induced DNA adducts in Wistar rats." in: Molecular nutrition & food research, Vol. 60, Issue 9, pp. 1956-66, (2016) (PubMed).
: "Benzopyrene, a major polyaromatic hydrocarbon in smoke fume, mobilizes Langerhans cells and polarizes Th2/17 responses in epicutaneous protein sensitization through the aryl hydrocarbon receptor." in: International immunopharmacology, Vol. 36, pp. 111-7, (2016) (PubMed).
: "Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models." in: Archives of toxicology, Vol. 91, Issue 5, pp. 2135-2150, (2016) (PubMed).
: "Biochemical response of crayfish Astacus leptodactylus exposed to textile wastewater treated by indigenous white rot fungus Coriolus versicolor." in: Environmental science and pollution research international, Vol. 22, Issue 4, pp. 2987-93, (2015) (PubMed).
: "Apiaceous vegetable consumption decreases PhIP-induced DNA adducts and increases methylated PhIP metabolites in the urine metabolome in rats." in: The Journal of nutrition, Vol. 145, Issue 3, pp. 442-51, (2015) (PubMed).
Synonyms and alternative names related to CYP1A1
cytochrome P450 family 1 subfamily A member 1 (CYP1A1), cytochrome P450 1A1 (CpipJ_CPIJ010542), cytochrome P450, family 1, subfamily a, polypeptide 1 (Cyp1a1), cytochrome P450 1A1 (CYP1A1), cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), cytochrome P450 family 1 subfamily D polypeptide 1 (cyp1d1), cytochrome P4501A1 (CYP1A1), polycyclic hydrocarbon-inducible cytochrome P450c (LOC100328613), cytochrome P450, family 1, subfamily A (cyp1a), cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 (CYP1A1), cytochrome P450 1A1 (LOC102129994), cytochrome P450 family 1 subfamily A member 1 L homeolog (cyp1a1.L), AHH, ahh, AHRR, ahrr, CP11, cp11, CYP1, cyp1, cyp1a, cyp1a1, CYP1A1, Cyp1a2, Cyp45c, Cypc45c, CYPIA1, P-450MC, P1-450, p1-450, P450-1, P450-C, p450-c, P450DX, p450dx, wu:fb63b04, zfCYP1A, zgc:109747Protein level used designations for CYP1A1
- CYPIA1
- aryl hydrocarbon hydroxylase
- cytochrome P1-450, dioxin-inducible
- cytochrome P450 1A1
- cytochrome P450 form 6
- cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1
- cytochrome P450-C
- cytochrome P450-P1
- flavoprotein-linked monooxygenase
- xenobiotic monooxygenase
- aromatic compound inducible
- cytochrome P450 family 1 subfamily a polypeptide 2
- cytochrome P450 subfamily I, polypeptide 1
- cytochrome P450, 1a1, aromatic compound inducible
- cytochrome P450 CYP1A1
- P-450 PHPAH1
- P450 LM6
- P450 isozyme 6
- cytochrome P-450 PHPAH1
- cytochrome P450 LM6
- cytochrome P450 isozyme 6
- P450MT2
- P450form6
- cytochrome P1-450
- cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c)
- cytochrome P450, 1a1
- cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c)
- cytochrome P450MT2
- dioxin-inducible
- microsomal monooxygenase
- cytochrome P450, subfamily I, polypeptide 1
- cytochrome P-450
- cytochrome P450 family 1 subfamily A member 1 L homeolog
- cytochrome P450, family 1, subfamily A, polypeptide 1
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