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Browse our CYP3A5 Proteins (CYP3A5)

Full name:
Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 Proteins (CYP3A5)
On are 3 Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5) Proteins from 3 different suppliers available. Additionally we are shipping CYP3A5 Antibodies (59) and CYP3A5 Kits (12) and many more products for this protein. A total of 80 CYP3A5 products are currently listed.
list all proteins Gene Name GeneID UniProt
CYP3A5 1577 P20815

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Human Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5) interaction partners

  1. The present study evaluated the ability of a Saccharomyces cerevisiae expression system to predict the pharmacokinetic (PK) activity of a calcium channel blocker in patients with distinct cytochrome P450 3A5 (CYP3A5) polymorphisms.

  2. In the CYP3A5*3/*3 group, the concentration of tacrolimus was significantly higher in men than in women in Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients.

  3. There are no significant differences in serum creatinine, haematocrit and albumin (show ALB Proteins) values between CYP3A5 expressers and non-expressers.

  4. population pharmacokinetic analysis identified that the combined genotype of CYP3A5-POR (show POR Proteins) was the only covariant for the apparent clearance of tacrolimus

  5. The possible association of CYP3A5*3 and CYP3A4*1G polymorphisms on CYP3A activity.

  6. The GG and TT genotypes in CYP3A5*3 and ABCB1 (show ABCB1 Proteins) C3435T, respectively, were linked with higher TPC (show CCDC6 Proteins).

  7. CYP3A5 single nucleotide polymorphisms are associated with Clopidogrel Resistance in Acute Ischemic Stroke.

  8. There was no significant correlation between CYP3A5 rs776746 polymorphism and major adverse events of clopidogrel therapy. [Meta-Analysis]

  9. pharmacokinetics of once-daily tacrolimus formulation in relation to polymorphisms of the donor cytochrome P450 family 3 sub-family A polypeptide 5 (CYP3A5) gene and recipient adenosine triphosphate-binding cassette sub-family B member 1 (ABCB1 (show ABCB1 Proteins)) gene in 80 consecutive living-donor liver transplant recipients

  10. CYP3A5 (6986A > G) genotype, rather than MDR-1 (2677G > A/T) variant, has an impact on tacrolimus pharmacokinetics

CYP3A5 Protein Profile

Protein Summary

This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene.

Alternative names and synonyms associated with CYP3A5

  • cytochrome P450, family 3, subfamily A, polypeptide 5 (CYP3A5)
  • CP35 protein
  • CYPIIIA5 protein
  • P450PCN3 protein
  • PCN3 protein

Protein level used designations for CYP3A5

cytochrome P450 3A5 , aryl hydrocarbon hydroxylase , cytochrome P450 HLp2 , cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5 , cytochrome P450-PCN3 , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase

737374 Pan troglodytes
1577 Homo sapiens
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