Browse our Dihydrodiol Dehydrogenase Proteins (DDH)

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Dihydrodiol Dehydrogenase Proteins (DDH)
On are 13 Dihydrodiol Dehydrogenase (DDH) Proteins from 6 different suppliers available. Additionally we are shipping Dihydrodiol Dehydrogenase Antibodies (49) and Dihydrodiol Dehydrogenase Kits (5) and many more products for this protein. A total of 79 Dihydrodiol Dehydrogenase products are currently listed.
list all proteins Gene Name GeneID UniProt
DDH 1645 Q04828

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Dihydrodiol Dehydrogenase Proteins (DDH) by Origin

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Top referenced Dihydrodiol Dehydrogenase Proteins

  1. Human DDH Protein expressed in Escherichia coli (E. coli) - ABIN666955 : Zhang, Dufort, Rheault, Luu-The: Characterization of a human 20alpha-hydroxysteroid dehydrogenase. in Journal of molecular endocrinology 2000 (PubMed)
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More Proteins for Dihydrodiol Dehydrogenase Interaction Partners

Human Dihydrodiol Dehydrogenase (DDH) interaction partners

  1. the present study suggests that AKR1C1, AKR1C2 (show AKR1C2 Proteins), AKR1C3 (show AKR1C3 Proteins), and AKR1C4 (show AKR1C4 Proteins) are closely associated with drug resistance to both CDDP and 5FU, and that mefenamic acid, an inhibitor of AKR1C, restores sensitivity through inhibition of drug-resistance in human cancer cells.

  2. Activation of AKR1C1/ERbeta (show ESR2 Proteins) induces apoptosis by downregulation of c-FLIP (show CFLAR Proteins) in prostate cancer cells.

  3. results suggest a gender-specific modulatory effect of AKR1C1 on anxiety levels, most likely through changes in progesterone and allopregnanolone levels within and outside the brain

  4. Studies indicate that mutations in aldo-keto reductase family 1 (AKR1) enzymes AKR1C1 and AKR1C4 (show AKR1C4 Proteins) are responsible for sexual development dysgenesis and mutations in AKR1D1 (show AKR1D1 Proteins) are causative in bile-acid deficiency.

  5. activation of the Nrf2 (show GABPA Proteins)/AKR1C axis may contribute to oxaliplatin resistance in gastric carcinoma

  6. The involvement of up-regulated AKR1C1, AKR1C3 (show AKR1C3 Proteins) and proteasome in CDDP resistance of colon cancers.

  7. Which promoted significant reduction of AKR1C1 and AKR1C2 (show AKR1C2 Proteins) expression.

  8. Data suggest that interleukin-1beta facilitates progesterone metabolism in cervical fibroblasts by regulating expression of AKR1C1 and AKR1C2 (show AKR1C2 Proteins).

  9. enhanced metabolism of progesterone by SRD5A1 (show SRD5A1 Proteins) and the 20alpha-HSD and 3alpha/beta-HSD (show CHST3 Proteins) activities of AKR1C1, AKR1C2 (show AKR1C2 Proteins) and AKR1C3 (show AKR1C3 Proteins)

  10. analysis of single nucleotide polymorphisms of AKR1C1 and AKR1C2 (show AKR1C2 Proteins)

Dihydrodiol Dehydrogenase (DDH) Protein Profile

Protein Summary

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Alternative names and synonyms associated with Dihydrodiol Dehydrogenase (DDH)

  • aldo-keto reductase family 1, member C1 (AKR1C1)
  • aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1)
  • 2-ALPHA-HSD protein
  • 20-ALPHA-HSD protein
  • C9 protein
  • DD1 protein
  • DD1/DD2 protein
  • DDH protein
  • DDH1 protein
  • H-37 protein
  • HAKRC protein
  • HBAB protein
  • MBAB protein

Protein level used designations for DDH

20 alpha-hydroxysteroid dehydrogenase , 20-alpha-hydroxysteroid dehydrogenase , aldo-keto reductase C , aldo-keto reductase family 1 member C1 , chlordecone reductase homolog HAKRC , dihydrodiol dehydrogenase 1 , dihydrodiol dehydrogenase 1/2 , dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase , dihydrodiol dehydrogenase isoform DD1 , hepatic dihydrodiol dehydrogenase , high-affinity hepatic bile acid-binding protein , indanol dehydrogenase , trans-1,2-dihydrobenzene-1,2-diol dehydrogenase , type II 3-alpha-hydroxysteroid dehydrogenase , 20-alpha-HSD , aldo-keto reductase family 1 member C1 homolog

1645 Homo sapiens
100171658 Pongo abelii
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