Browse our anti-Synaptotagmin II (SYT2) Antibodies

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anti-Synaptotagmin II Antibodies (SYT2)
On are 77 Synaptotagmin II (SYT2) Antibodies from 19 different suppliers available. Additionally we are shipping Synaptotagmin II Proteins (7) and many more products for this protein. A total of 89 Synaptotagmin II products are currently listed.
mKIAA4194, R74640, RATSYNII, si:ch211-236j4.1, SYNII, SytII

Most Popular Reactivities for anti-Synaptotagmin II (SYT2) Antibodies

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Top referenced anti-Synaptotagmin II Antibodies

  1. Rat (Rattus) Monoclonal SYT2 Primary Antibody for IP, WB - ABIN1449191 : Heald, Nogales: Microtubule dynamics. in Journal of cell science 2002 (PubMed)
    Show all 5 references for 1449191

  2. Human Polyclonal SYT2 Primary Antibody for IF - ABIN401604 : Cnops, Hu, Burnat, Arckens: Influence of binocular competition on the expression profiles of CRMP2, CRMP4, Dyn I, and Syt I in developing cat visual cortex. in Cerebral cortex (New York, N.Y. : 1991) 2008 (PubMed)
    Show all 3 references for 401604

  3. Chicken Monoclonal SYT2 Primary Antibody for WB - ABIN968922 : Geppert, Archer, Südhof: Synaptotagmin II. A novel differentially distributed form of synaptotagmin. in The Journal of biological chemistry 1991 (PubMed)
    Show all 3 references for 968922

  4. Human Polyclonal SYT2 Primary Antibody for IP, IHC - ABIN1742202 : Johnson, Franz, Kuhn, Furness, Rüttiger, Münkner, Rivolta, Seward, Herschman, Engel, Knipper, Marcotti: Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses. in Nature neuroscience 2009 (PubMed)
    Show all 3 references for 1742202

More Antibodies against Synaptotagmin II Interaction Partners

Zebrafish Synaptotagmin II (SYT2) interaction partners

  1. knockdown of synaptotagmin 2 (syt2) reduces synchronous release, whereas knockdown of synaptotagmin 7 (syt7 (show SYT7 Antibodies)) reduces the asynchronous component of release.

Human Synaptotagmin II (SYT2) interaction partners

  1. the extended synaptotagmins (E-Syts), endoplasmic reticulum (ER) proteins that function as PtdIns(4,5)P2- and Ca(2 (show CA2 Antibodies)+)-regulated tethers to the Pplasma membrane.

  2. SYT2 mutations cause a novel complex presynaptic congenital myasthenic syndrome characterized by motor neuropathy causing lower limb wasting and foot deformities, reflex potentiation following exercise and a prolonged period of posttetanic potentiation

  3. Synaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathy.

  4. Human SytII is not an effective receptor for Botulinum neurotoxin D-C.

  5. synaptotagmin-II is not a high affinity receptor for BoNT/B (show BoNT/B Antibodies) and G due to a phenylalanine to leucine mutation in its luminal domain present only in humans and chimpanzees

  6. role for synaptotagmin II as calcium-sensor during phagocytosis and secretion in neutrophils

  7. both synaptotagmins I and II can interact with the syntaxin/synaptosomal-associated protein of 25 kDa (SNAP-25 (show SNAP25 Antibodies)) dimer

  8. WNK1 (show WNK1 Antibodies) selectively binds to and phosphorylates synaptotagmin 2 (Syt2) within its calcium binding C2 domains. Endogenous WNK1 (show WNK1 Antibodies) and Syt2 coimmunoprecipitate and colocalize on a subset of secretory granules in INS-1 (show FOXM1 Antibodies) cells.

  9. A recombinant fragment from the luminal domain of the human receptor protein syt (show SS18 Antibodies) II can bind specifically to botulinum neurotoxin B and its Hc domain.

  10. Mutation of overexpressed Syt2 transgene leaves intrinsic calcium sensitivity of vesicles intact while it destabilizes the readily releasable pool of vesicles and loosens the tight coupling between calcium influx and release.

Mouse (Murine) Synaptotagmin II (SYT2) interaction partners

  1. we identify Syt2 as a functionally important Ca(2 (show CA2 Antibodies)+) sensor at fast-releasing inhibitory synapses, and show that Syt1 (show SYT1 Antibodies) and Syt2 can redundantly control transmitter release at specific brain synapses

  2. demonstrates a developmental Syt1 (show SYT1 Antibodies)-Syt2 isoform switch at an identified synapse, a mechanism that could fine-tune the speed, reliability, and plasticity of transmitter release at fast releasing CNS synapses.

  3. the combined inactivation of all 3 E-Syt (show SS18 Antibodies) genes has no effect on mouse viability or fertility.

  4. The 2.3-A structure of a ternary complex of botulinum neurotoxin type B (show BoNT/B Antibodies) bound to both its protein receptor synaptotagmin II and its ganglioside receptor GD1a, is reported.

  5. Synaptotagmins 1 and 2 as mediators of rapid exocytosis at nerve terminals: the dyad hypothesis

  6. Syt2 make it an excellent marker for analyzing the development and plasticity of perisomatic inhibitory innervations onto both excitatory and inhibitory neurons in the visual cortex.

  7. Syt2 increases the dynamic range of synapses by driving release with a high Ca(2 (show CA2 Antibodies))+ cooperativity, as well as by suppressing a remaining, near-linear Ca(2 (show CA2 Antibodies))+ sensor.

  8. Transient expression of Syt2 is no longer detected in cochlear inner hair cells (IHCs) after the onset of hearing, indicating that the most common calcium-sensors in central nervous system synapses are not involved in mature IHC ribbon synapse.

  9. SYT2 was a negative regulator of chemotaxis

  10. The readily releasable pool was rescued by Syt2 overexpression. The kinetics of fusion was slightly slower than in cells expressing Syt1. Syt2 has a lower Ca2+ affinity for phospholipid binding than Syt1 because of a difference in the C2A domain.

Synaptotagmin II (SYT2) Antigen Profile

Antigen Summary

Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994

Alternative names and synonyms associated with Synaptotagmin II (SYT2)

  • synaptotagmin-2-like (LOC100146749) antibody
  • synaptotagmin IIa (syt2a) antibody
  • synaptotagmin II (syt2) antibody
  • synaptotagmin II (SYT2) antibody
  • synaptotagmin II (Syt2) antibody
  • synaptotagmin-like 2 (SYTL2) antibody
  • mKIAA4194 antibody
  • R74640 antibody
  • RATSYNII antibody
  • si:ch211-236j4.1 antibody
  • SYNII antibody
  • SytII antibody

Protein level used designations for anti-Synaptotagmin II (SYT2) Antibodies

synaptotagmin II , synaptotagmin 2 , synaptotagmin-2 , sytII

100146749 Equus caballus
567877 Danio rerio
100158469 Xenopus (Silurana) tropicalis
100511582 Sus scrofa
100594116 Nomascus leucogenys
127833 Homo sapiens
20980 Mus musculus
24805 Rattus norvegicus
100300626 Bos taurus
396327 Gallus gallus
485154 Canis lupus familiaris
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