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SYT2 Products

(Synaptotagmin II (SYT2))

Categories

Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM, Mar 2008].

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Featured SYT2 Categories

SYT2 Antibodies

High quality antibodies with extensive validation data.

SYT2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SYT2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN566793
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IP, IHC
Validations
  • (3)
  • (2)
Cat. No. ABIN1742202
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN6265413
Quantity 100 μL
Datasheet Datasheet

Recommended SYT2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322019
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3073609
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134099
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SYT2 products

Whitemarsh, Strathman, Chase, Stankewicz, Tepp, Johnson, Pellett: "Novel application of human neurons derived from induced pluripotent stem cells for highly sensitive botulinum neurotoxin detection." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 126, Issue 2, pp. 426-35, (2012) (PubMed).

Culver, Savas, Park, Choi, Zheng, Zeitlin, Yates, Tanese: "Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis." in: The Journal of biological chemistry, Vol. 287, Issue 26, pp. 21599-614, (2012) (PubMed).

Johnson, Franz, Kuhn, Furness, Rüttiger, Münkner, Rivolta, Seward, Herschman, Engel, Knipper, Marcotti: "Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses." in: Nature neuroscience, Vol. 13, Issue 1, pp. 45-52, (2009) (PubMed).

Young, Neher: "Synaptotagmin has an essential function in synaptic vesicle positioning for synchronous release in addition to its role as a calcium sensor." in: Neuron, Vol. 63, Issue 4, pp. 482-96, (2009) (PubMed).

Cnops, Hu, Burnat, Arckens: "Influence of binocular competition on the expression profiles of CRMP2, CRMP4, Dyn I, and Syt I in developing cat visual cortex." in: Cerebral cortex (New York, N.Y. : 1991), Vol. 18, Issue 5, pp. 1221-31, (2008) (PubMed).

Gustavsson, Lao, Maximov, Chuang, Kostromina, Repa, Li, Radda, Südhof, Han: "Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 10, pp. 3992-7, (2008) (PubMed).

Lynch, Gerona, Larsen, Marcia, Mitchell, Martin: "Synaptotagmin C2A loop 2 mediates Ca2+-dependent SNARE interactions essential for Ca2+-triggered vesicle exocytosis." in: Molecular biology of the cell, Vol. 18, Issue 12, pp. 4957-68, (2007) (PubMed).

Kida, Sakaguchi, Fukuda, Mikoshiba, Mihara: "Membrane topogenesis of a type I signal-anchor protein, mouse synaptotagmin II, on the endoplasmic reticulum." in: The Journal of cell biology, Vol. 150, Issue 4, pp. 719-30, (2000) (PubMed).

Osborne, Herreros, Bastiaens, Schiavo: "Calcium-dependent oligomerization of synaptotagmins I and II. Synaptotagmins I and II are localized on the same synaptic vesicle and heterodimerize in the presence of calcium." in: The Journal of biological chemistry, Vol. 274, Issue 1, pp. 59-66, (1999) (PubMed).

Geppert, Archer, Südhof: "Synaptotagmin II. A novel differentially distributed form of synaptotagmin." in: The Journal of biological chemistry, Vol. 266, Issue 21, pp. 13548-52, (1991) (PubMed).

Synonyms and alternative names related to SYT2

synaptotagmin 2 (SYT2), synaptotagmin 2 (Syt2), synaptotagmin II (Syt2), synaptotagmin IIa (syt2a), synaptotagmin 2 (syt2), mKIAA4194, R74640, RATSYNII, si:ch211-236j4.1, SYNII, SytII

Protein level used designations for SYT2

  • synaptotagmin 2
  • synaptotagmin-2
  • sytII
  • synaptotagmin II
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