Browse our CARD11 Proteins (CARD11)

Full name:
Caspase Recruitment Domain Family, Member 11 Proteins (CARD11)
On are 4 Caspase Recruitment Domain Family, Member 11 (CARD11) Proteins from 3 different suppliers available. Additionally we are shipping CARD11 Antibodies (73) and many more products for this protein. A total of 84 CARD11 products are currently listed.
0610008L17Rik, 2410011D02Rik, BENTA, BIMP3, CARD11, CARMA1, LOC100232755, PPBL
list all proteins Gene Name GeneID UniProt
Rat CARD11 CARD11 100363332  
CARD11 84433 Q9BXL7
CARD11 108723 Q8CIS0

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CARD11 Proteins (CARD11) by Origin

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More Proteins for CARD11 Interaction Partners

Human Caspase Recruitment Domain Family, Member 11 (CARD11) interaction partners

  1. NF-kappaB (show NFKB1 Proteins) and beta-catenin (show CTNNB1 Proteins) signaling by gain-of-function mutations in CARMA1 augments WNT (show WNT2 Proteins) stimulation and is required for regulating the expression of distinct NF-kappaB (show NFKB1 Proteins) target genes to trigger cell-intrinsic and extrinsic processes that promote DLBCL lymphomagenesis

  2. CARD11 mutations are rare in patients with CD5 (show CD5 Proteins)+ DLBCL.

  3. results define molecular determinants that control the production of Lin(Ub)n-Bcl10 (show BCL10 Proteins), an important signaling intermediate in TCR and oncogenic CARD11 signaling.

  4. We evaluated the relationship between rs4722404 polymorphism in the CARD11 gene, and the risk and clinical features of psoriasis vulgaris in a southern Chinese Han cohort.We identified no association between the SNP and risk of psoriasis vulgaris.

  5. single amino acid oncogenic CARD11 mutations can perturb or bypass the action of redundant inhibitory REs to achieve the level of hyperactive CARD11 signaling required to support lymphoma growth.

  6. Cooperative Control of Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling by an Unusual Array of Redundant Repressive Elements.

  7. CARMA1- and MyD88 (show MYD88 Proteins)-dependent activation of Jun (show JUN Proteins)/ATF-type AP-1 (show FOSB Proteins) complexes is a hallmark of ABC (show ABCB6 Proteins) diffuse large B-cell lymphomas.

  8. Data show that caspase recruitment domain-containing protein 11/B-cell CLL/lymphoma 10 (show BCL10 Proteins)/mucosa-associated lymphoid tissue lymphoma translocation gene 1 (show MALT1 Proteins) signaling drives lymphoproliferation (show FAS Proteins) through NF-kappa B (show NFKB1 Proteins) and c-Jun N-terminal kinase activation.

  9. CARD11-mediated alterations in NF-kappaB (show NFKB1 Proteins) signaling may be an early event in the development of cutaneous squamous cell carcinoma

  10. Taken together, our data indicate that miR (show MLXIP Proteins)-539 is a novel regulator of migration and invasion in human thyroid cancer cells by targeting CARMA1.

Mouse (Murine) Caspase Recruitment Domain Family, Member 11 (CARD11) interaction partners

  1. synergistic activity of Card11 mutant and Bcl6 (show BCL6 Proteins) in the development of diffuse large B-cell lymphoma in a mouse model

  2. CARMA1 clustering through SH3-GUK domain interactions is required for its activation of NF-kappaB (show NFKB1 Proteins) signalling

  3. data suggest that Carma1 and MALT1 play previously unappreciated roles in the activation of mTOR signaling in T cells after engagement of the TCR.

  4. CARMA1 CARD shows the first homo-dimeric structure of CARD formed by a disulfide bond and reveals a possible biologically important homo-dimerization mechanism

  5. Data indicate that caspase recruitment domain-containing protein 11 (CARD11) is involved in the pathogenesis of collagen-induced arthritis (CIA (show NCOA5 Proteins)) by formation of the CARD11/Bcl10 (show BCL10 Proteins) complex and enhancement of the Th17 cell response.

  6. Genetic approach demonstrates a critical role for the CARD function of CARMA1 in Treg cell development in vivo.

  7. both CARMA1 CARD and BCL10 CARD easily self-oligomerized under physiological conditions.

  8. Findings show that regulation of CARD11 signaling is a critical switch governing the decision between death and proliferation in antigen-stimulated mature B cells.

  9. TCR/CARMA1/NF-kappaB (show NFKB1 Proteins) controls completion of Th17 differentiation.

  10. These studies provide molecular insight into the assembly of CARMA1 and BCL10.

CARD11 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Alternative names and synonyms associated with CARD11

  • caspase recruitment domain family, member 11 (CARD11)
  • caspase recruitment domain family, member 11 (LOC100232755)
  • caspase recruitment domain family, member 11 (LOC100354145)
  • caspase recruitment domain family, member 11 (LOC100363332)
  • caspase recruitment domain family, member 11 (card11)
  • caspase recruitment domain family, member 11 (Card11)
  • 0610008L17Rik protein
  • 2410011D02Rik protein
  • BENTA protein
  • BIMP3 protein
  • CARD11 protein
  • CARMA1 protein
  • LOC100232755 protein
  • PPBL protein

Protein level used designations for CARD11

caspase recruitment domain family, member 11 , caspase recruitment domain-containing protein 11-like , CARD-containing MAGUK protein 1 , bcl10-interacting maguk protein 3 , carma 1 , caspase recruitment domain-containing protein 11

463235 Pan troglodytes
100232755 Taeniopygia guttata
100354145 Oryctolagus cuniculus
100363332 Rattus norvegicus
100400232 Callithrix jacchus
100550812 Meleagris gallopavo
100565989 Anolis carolinensis
100591575 Nomascus leucogenys
84433 Homo sapiens
108723 Mus musculus
489887 Canis lupus familiaris
515377 Bos taurus
416476 Gallus gallus
304314 Rattus norvegicus
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