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Browse our CARD11 Proteins (CARD11)

Full name:
Caspase Recruitment Domain Family, Member 11 Proteins (CARD11)
On www.antibodies-online.com are 4 Caspase Recruitment Domain Family, Member 11 (CARD11) Proteins from 3 different suppliers available. Additionally we are shipping CARD11 Antibodies (71) and CARD11 Kits (6) and many more products for this protein. A total of 88 CARD11 products are currently listed.
Synonyms:
0610008L17Rik, 2410011D02Rik, BENTA, BIMP3, CARD11, CARMA1, LOC100232755, PPBL
list all proteins Gene Name GeneID UniProt
Rat CARD11 CARD11 100363332  
CARD11 84433 Q9BXL7
CARD11 108723 Q8CIS0

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CARD11 Proteins (CARD11) by Origin

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More Proteins for CARD11 Interaction Partners

Human Caspase Recruitment Domain Family, Member 11 (CARD11) interaction partners

  1. single amino acid oncogenic CARD11 mutations can perturb or bypass the action of redundant inhibitory REs to achieve the level of hyperactive CARD11 signaling required to support lymphoma growth.

  2. Cooperative Control of Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling by an Unusual Array of Redundant Repressive Elements.

  3. CARMA1- and MyD88 (show MYD88 Proteins)-dependent activation of Jun (show JUN Proteins)/ATF-type AP-1 (show FOSB Proteins) complexes is a hallmark of ABC (show ABCB6 Proteins) diffuse large B-cell lymphomas.

  4. Data show that caspase recruitment domain-containing protein 11/B-cell CLL/lymphoma 10 (show BCL10 Proteins)/mucosa-associated lymphoid tissue lymphoma translocation gene 1 (show MALT1 Proteins) signaling drives lymphoproliferation (show FAS Proteins) through NF-kappa B (show NFKB1 Proteins) and c-Jun N-terminal kinase activation.

  5. CARD11-mediated alterations in NF-kappaB (show NFKB1 Proteins) signaling may be an early event in the development of cutaneous squamous cell carcinoma

  6. Taken together, our data indicate that miR (show MLXIP Proteins)-539 is a novel regulator of migration and invasion in human thyroid cancer cells by targeting CARMA1.

  7. CARMA1 clustering through SH3-GUK domain interactions is required for its activation of NF-kappaB (show NFKB1 Proteins) signalling

  8. Both carried homozygous germline mutations in CARD11 (p.Cys150*), impairing NF-kappaB (show NFKB1 Proteins) signaling and IL-2 (show IL2 Proteins) production

  9. Three patients have been described with mild B-cell lymphocytosis and a CARD11 C49Y missense mutation.

  10. Overexpression of CARMA-BCL10 (show BCL10 Proteins)-MALT in T-ALL may contribute to the constitutive cleavage and inactivation of A20 (show TNFAIP3 Proteins), which enhances NF-kappaB (show NFKB1 Proteins) signaling and may be related to T-ALL pathogenesis.

Mouse (Murine) Caspase Recruitment Domain Family, Member 11 (CARD11) interaction partners

  1. CARMA1 clustering through SH3-GUK domain interactions is required for its activation of NF-kappaB (show NFKB1 Proteins) signalling

  2. data suggest that Carma1 and MALT1 play previously unappreciated roles in the activation of mTOR signaling in T cells after engagement of the TCR.

  3. CARMA1 CARD shows the first homo-dimeric structure of CARD formed by a disulfide bond and reveals a possible biologically important homo-dimerization mechanism

  4. Data indicate that caspase recruitment domain-containing protein 11 (CARD11) is involved in the pathogenesis of collagen-induced arthritis (CIA (show NCOA5 Proteins)) by formation of the CARD11/Bcl10 (show BCL10 Proteins) complex and enhancement of the Th17 cell response.

  5. Genetic approach demonstrates a critical role for the CARD function of CARMA1 in Treg cell development in vivo.

  6. both CARMA1 CARD and BCL10 CARD easily self-oligomerized under physiological conditions.

  7. Findings show that regulation of CARD11 signaling is a critical switch governing the decision between death and proliferation in antigen-stimulated mature B cells.

  8. TCR/CARMA1/NF-kappaB (show NFKB1 Proteins) controls completion of Th17 differentiation.

  9. These studies provide molecular insight into the assembly of CARMA1 and BCL10.

  10. Upregulation of CARMA1 in vivo results in Th2 cell-mediated inflammation. Mice expressing constitutively active CARMA1 have elevated IL-4 (show IL4 Proteins), IL-5 (show IL5 Proteins), and IL-10 (show IL10 Proteins) and spontaneously develop pulmonary inflammation and eosinophilia.

CARD11 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Alternative names and synonyms associated with CARD11

  • caspase recruitment domain family, member 11 (CARD11)
  • caspase recruitment domain family, member 11 (LOC100232755)
  • caspase recruitment domain family, member 11 (LOC100354145)
  • caspase recruitment domain family, member 11 (LOC100363332)
  • caspase recruitment domain family, member 11 (card11)
  • caspase recruitment domain family, member 11 (Card11)
  • 0610008L17Rik protein
  • 2410011D02Rik protein
  • BENTA protein
  • BIMP3 protein
  • CARD11 protein
  • CARMA1 protein
  • LOC100232755 protein
  • PPBL protein

Protein level used designations for CARD11

caspase recruitment domain family, member 11 , caspase recruitment domain-containing protein 11-like , CARD-containing MAGUK protein 1 , bcl10-interacting maguk protein 3 , carma 1 , caspase recruitment domain-containing protein 11

GENE ID SPECIES
463235 Pan troglodytes
100232755 Taeniopygia guttata
100354145 Oryctolagus cuniculus
100363332 Rattus norvegicus
100400232 Callithrix jacchus
100550812 Meleagris gallopavo
100565989 Anolis carolinensis
100591575 Nomascus leucogenys
84433 Homo sapiens
108723 Mus musculus
489887 Canis lupus familiaris
515377 Bos taurus
416476 Gallus gallus
304314 Rattus norvegicus
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