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Browse our CREB1 Proteins (CREB1)

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CAMP Responsive Element Binding Protein 1 Proteins (CREB1)
On are 14 CAMP Responsive Element Binding Protein 1 (CREB1) Proteins from 7 different suppliers available. Additionally we are shipping CREB1 Antibodies (521) and CREB1 Kits (29) and many more products for this protein. A total of 597 CREB1 products are currently listed.
2310001E10Rik, 3526402H21Rik, AV083133, Creb, Creb-1, creb1, zgc:55598
list all proteins Gene Name GeneID UniProt
CREB1 1385 P16220
CREB1 12912 Q01147
CREB1 81646 P15337

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CREB1 Proteins (CREB1) by Origin

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Top referenced CREB1 Proteins

  1. Human CREB1 Protein expressed in Wheat germ - ABIN1350285 : Yin, Li, Yang, Gao, Sun, Li: Detection of CREB phosphorylation via Zr (IV) ion mediated signal amplification. in Biosensors & bioelectronics 2014 (PubMed)

More Proteins for CREB1 Interaction Partners

Silk Worm CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. CREB is positively regulated by PKA and calcium-sensitive calcineurin and negatively by PKC.

  2. The sequence of the CREB gene contains a 88 bp 5' UTR, a 783 bp open reading frame encoding 261 amino acids and a 348 bp 3' UTR.

Rabbit CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. Data indicate increasing expression for CREB, ATF1 (show AFT1 Proteins), and ATF3 (show ATF3 Proteins) during gastrulation.

Human CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. These results suggest that the HIPK2 (show HIPK2 Proteins)-phospho-Ser271 CREB axis is a new arsenic-responsive CREB activation mechanism in parallel with the PKA-phospho-Ser133 CREB axis.

  2. There were decreased levels of Gsa (show GNAS Proteins), FOXF1 (show FOXF1 Proteins), CREB1, and phosphorylated CREB1 proteins in intestinal muscle layers of patients with chronic intestinal pseudo-obstruction, compared with tissues from controls.

  3. Regulatory elements for both IRF-1 (show IRF1 Proteins) (-1019 to -1016) and CREB (-1198 to -1195), specific to the distal THBS1 (show THBS1 Proteins) promoter, were required for leptin (show LEP Proteins)-induced TSP-1 (show THBS1 Proteins) transcription.

  4. The results suggest that Sirt2 (show SIRT2 Proteins) plays a crucial role in neuronal differentiation via the ERK (show EPHB2 Proteins)-CREB signaling pathway.

  5. revealed more than 170 NFAT (show NFATC1 Proteins)-associated proteins, half of which are involved in transcriptional regulation. Among them are many hitherto unknown interaction partners of NFATc1 (show NFATC1 Proteins) and NFATc2 (show NFAT1 Proteins) in T cells, such as Raptor (show RPTOR Proteins), CHEK1 (show CHEK1 Proteins), CREB1, RUNX1 (show RUNX1 Proteins), SATB1 (show SATB1 Proteins), Ikaros (show IKZF1 Proteins), and Helios (show ZNFN1A2 Proteins).

  6. Here, the authors report that varicella-zoster virus infection also induced CREB phosphorylation in fibroblasts and that XX-650-23, a newly identified inhibitor of the phosphorylated-CREB (pCREB) interaction with p300/CBP (show CREBBP Proteins), restricted cell-cell spread of varicella-zoster virus in vitro.

  7. all of these features of CREB in HL strongly support its role as a tumor suppressor gene that can decelerate cell proliferation by inhibiting the expression of several cell cycle-related genes.

  8. observations indicate that induced expression of miR (show MLXIP Proteins)-15b is modulated by c-Rel (show NFkBP65 Proteins) and CREB in response to JEV infection

  9. A critical role was determined for CREB in cell proliferation, cell survival and apoptosis in B-cell precursor acute lymphoblastic leukemia cells.

  10. SMND-309 can prevent neuronal cell death in vitro via activation of the PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins)/CREB-signalling pathway.

Mouse (Murine) CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. Activation of PTHrP-cyclic AMP (show TMPRSS5 Proteins)-CREB1 signaling following p53 (show TP53 Proteins) loss is essential for osteosarcoma initiation and maintenance.

  2. We propose that phosphorylation-dependent regulation of DNA binding activity evolved as a tunable mechanism to control CREB transcriptional output and promote metabolic homeostasis in response to rapidly changing environmental conditions.

  3. The present study provides the first critical in vivo evidence showing a causal link between epigenetic modification of miR (show MLXIP Proteins)-10a mediated by HDAC3 (show HDAC3 Proteins) and the development of diabetic nephropathy, and these results elucidate that HDAC3 (show HDAC3 Proteins)/miR (show MLXIP Proteins)-10a/CREB1 serves as a new mechanism underlying kidney injury, providing potential therapeutic targets in type 2 diabetes

  4. Expression levels of brain derived neurotrophic factor, postsynaptic density 95, and p-cyclic-AMP response element binding protein levels were significantly elevated in the testosterone (T) group, but flutamide reduced the T-induced effects in these biomarkers to control levels.

  5. results identify new DNA sequences that are well-bound by CREB1 and ATF1 (show AFT1 Proteins) only when they contain 5mC or 5hmC. Analysis of two X-ray structures examines the consequences of 5mC and 5hmC on DNA binding by CREB and FOS|JUN (show JUN Proteins)

  6. We conclude that upon ligand binding, TLR4 (show TLR4 Proteins) activates PI3K/Akt (show AKT1 Proteins) signaling to induce F-spondin (show SPON1 Proteins) expression, subsequently control CREB-mediated IL-6 (show IL6 Proteins) production to promote VSMC migration. These findings provide vital insights into the essential role of F-spondin (show SPON1 Proteins) in VSMC function and will be valuable for developing new therapeutic strategies against atherosclerosis.

  7. this paper shows that inhibition of autophagic flux regulates the alternation of microglial phenotype in cerebral ischemia by modulating the balance between NF-kappaB (show NFKB1 Proteins) and CREB

  8. MeHg-induced neuronal degeneration is caused by site-specific neural hyperactivity triggered by the activation of MAPK (show MAPK1 Proteins) and PKA/CREB pathways followed by c-fos and BDNF (show BDNF Proteins) upregulation.

  9. Data indicate that adenosine and CGS21680 upregulate CD39 (show ENTPD1 Proteins) and CD73 via E2F-1 (show E2F1 Proteins) and CREB.

  10. The mechanism of combined peanut skin extract and fish oil on memory was shown to be via the signaling pathways of brain-derived neurotrophic factor (show BDNF Proteins), ERK (show EPHB2 Proteins) MAP kinases, and CREB protein.

Pig (Porcine) CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. The expression of porcine Prdx6 (show PRDX6 Proteins) gene is up-regulated by C/EBPbeta (show CEBPB Proteins) and CREB.

  2. Results suggest that cerebral hypoxia results in differential regulation of CREB protein-mediated expression of proapoptotic and antiapoptotic proteins in the cerebral cortex of newborn piglets.

Cow (Bovine) CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. Data indicate that Ser738/742-to-glutamate (show GRIN2A Proteins) protein kinase D (show PRKD1 Proteins) mutant increased AngII-induced CREB protein and activating transcription factor 2 (show ATF2 Proteins) phosphorylation, and phospho-CREB binding to the steroidogenic acute regulatory protein (show STAR Proteins) promoter.

  2. SUMO-1 has a role in modifying cAMP-response element-binding protein CREB in prolonged hypoxia.

  3. dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB phosphorylation mediated by calcium-independent phospholipase A2 (show LYPLA1 Proteins)

  4. the p38-MAPK (show MAPK14 Proteins)/CREB pathway plays a critical role in TNFalpha (show TNF Proteins)-induced VCAM-1 (show VCAM1 Proteins) expression

Xenopus laevis CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. We found several conserved cis elements in the frog CRF genes including a cAMP response element (CRE), activator protein 1 binding sites, and glucocorticoid response elements

  2. p38 MAPK (show MAPK14 Proteins) and CREB function along the dorsal-ventral axis in mesoderm patterning. The phosphorylated form of CREB (S133) is distributed in a gradient along the dorsal-ventral mesoderm axis and the p38 MAPK (show MAPK14 Proteins) pathway mediates the phosphorylation of CREB.

Zebrafish CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. modulating CREB activity during early zebrafish development caused significant defects in neural proliferation, midbrain-hindbrain organization and body patterning

CREB1 Protein Profile

Protein Summary

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Alternative names and synonyms associated with CREB1

  • cAMP responsive element binding protein 1 (CREB1)
  • cAMP responsive element binding protein 1 (creb1)
  • cAMP responsive element binding protein 1 (Creb1)
  • cAMP responsive element binding protein 1 (LOC100351999)
  • cAMP responsive element binding protein 1a (creb1a)
  • cyclic AMP response element binding protein (CREB)
  • 2310001E10Rik protein
  • 3526402H21Rik protein
  • AV083133 protein
  • Creb protein
  • Creb-1 protein
  • creb1 protein
  • zgc:55598 protein

Protein level used designations for CREB1

cAMP responsive element binding protein 1 , cAMP responsive element binding protein , cyclic AMP-responsive element-binding protein 1 , CREB-1 , active transcription factor CREB , cAMP-response element-binding protein-1 , cAMP-responsive element-binding protein 1 , transactivator protein , Y protein , cAMP response element binding protein 1 , cAMP response element-binding protein , cyclic AMP-responsive element binding protein, delta , cyclic AMP-responsive DNA-binding protein

100066388 Equus caballus
407934 Xenopus (Silurana) tropicalis
459901 Pan troglodytes
692871 Bombyx mori
708717 Macaca mulatta
751585 Taeniopygia guttata
100294619 Pongo abelii
100351999 Oryctolagus cuniculus
100542127 Meleagris gallopavo
100586647 Nomascus leucogenys
1385 Homo sapiens
12912 Mus musculus
81646 Rattus norvegicus
395099 Gallus gallus
607922 Canis lupus familiaris
397449 Sus scrofa
281713 Bos taurus
379764 Xenopus laevis
573207 Danio rerio
443118 Ovis aries
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