Browse our CREB1 Proteins (CREB1)

On are 15 CAMP Responsive Element Binding Protein 1 (CREB1) Proteins from 8 different suppliers available. Additionally we are shipping CREB1 Antibodies (551) and CREB1 Kits (34) and many more products for this protein. A total of 632 CREB1 products are currently listed.
2310001E10Rik, 3526402H21Rik, AV083133, Creb, Creb-1, creb1, zgc:55598
list all proteins Gene Name GeneID UniProt
CREB1 1385 P16220
CREB1 12912 Q01147
CREB1 81646 P15337

CREB1 Proteins (CREB1) by Origin

More Proteins for CREB1 Interaction Partners

Silk Worm CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. CREB is positively regulated by PKA and calcium-sensitive calcineurin and negatively by PKC.

  2. The sequence of the CREB gene contains a 88 bp 5' UTR, a 783 bp open reading frame encoding 261 amino acids and a 348 bp 3' UTR.

Rabbit CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. Data indicate increasing expression for CREB, ATF1 (show AFT1 Proteins), and ATF3 (show ATF3 Proteins) during gastrulation.

Human CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. these data show the existence of functional CREB and C/EBP (show CEBPA Proteins) binding sites in the human RIC8B gene promoter, a particular distribution of these sites and demonstrate a relevant role of CREB in stimulating transcriptional activity of this gene.

  2. MALAT1 knockdown reduces reactive gliosis, Muller cell activation, and RGC survival in vivo and in vitro MALAT1-CREB binding maintains CREB phosphorylation by inhibiting PP2A (show PPP2R4 Proteins)-mediated dephosphorylation, which leads to continuous CREB signaling activation.

  3. aberrant activation of CREB-C/EBPdelta (show CEBPD Proteins) axis concurring to AML (show RUNX1 Proteins) onset by disrupting the myeloid cell differentiation process

  4. miR (show MLXIP Proteins)-27b-3p levels were found to be significantly negatively correlated with both NR5A2 (show NR5A2 Proteins) and CREB1 levels in breast cancer tissues.

  5. Interactions between GNB3 (show GNB3 Proteins), CREB1 and negative life events were revealed. Further evidence is provided about the role of the environment in genetic vulnerability to major depression.

  6. UCA1 promotes cisplatin/gemcitabine resistance in bladder cancer cells through CREB modulation of miR (show MLXIP Proteins)-196a-5p expression.

  7. Report a distinct group of myxoid mesenchymal neoplasms occurring in children or young adults with a predilection for intracranial locations with EWSR1 (show EWSR1 Proteins)-AFT1/CREB1/CREM (show CREM Proteins) fusions.

  8. CREB1/FoxA1 (show FOXA1 Proteins) signaling is a targetable driver of prostate cancer progression and serves as a biomarker of poor clinical outcomes.

  9. These results suggest that the HIPK2 (show HIPK2 Proteins)-phospho-Ser271 CREB axis is a new arsenic-responsive CREB activation mechanism in parallel with the PKA-phospho-Ser133 CREB axis.

  10. There were decreased levels of Gsa (show GNAS Proteins), FOXF1 (show FOXF1 Proteins), CREB1, and phosphorylated CREB1 proteins in intestinal muscle layers of patients with chronic intestinal pseudo-obstruction, compared with tissues from controls.

Mouse (Murine) CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. The NR2B (show GRIN2B Proteins)-CREB-miR212/132-CRTC1 (show CRTC1 Proteins)-CREB signal network plays an important role in the regulation of pain.

  2. Therefore, our study suggests that CREB and PSD95 (show DLG4 PLURAL_@42429@) are novel substrates of PERK (show EIF2AK3 PLURAL_@42429@), so inhibition of PERK (show EIF2AK3 PLURAL_@42429@) phosphorylation using GSK2656157 would be beneficial against memory impairment after TBI (show TBPL1 PLURAL_@42429@).

  3. Our results elucidate the specific role of the transcription factors CREB, SRF, and MEF2 (show MEF2C Proteins) in the depression and potentiation components of ODP in vivo, therefore better informing future attempts to find therapeutic targets for diseases where activity-dependent plasticity is disrupted.

  4. neuronal activity promotes CREB-dependent transcription by increasing the frequency of CREB binding to highly localized genome locations

  5. Expression of miR (show MLXIP Proteins)-26a or knockdown of Klf4 (show KLF4 Proteins) or Creb or C/ebpbeta (show CEBPB Proteins), attenuated the survival of Mycobacterium tuberculosis in macrophages.

  6. The findings indicate that the activation of sigma1R (show SIGMAR1 Proteins) can alleviate postpartum "depression" through increasing nNOS (show NOS1 Proteins)-NO-CREB activities.

  7. Data indicate that induction of a reactive oxygen species (ROS (show ROS1 Proteins))/p38 MAPK (show MAPK14 Proteins) - mediated feedback inhibitory pathway by oxy (show GCG Proteins)-cholesterol and steroid intermediates and products attenuates steroidogenesis via inhibition of cAMP responsive element binding protein (CREB) transcriptional activity.

  8. Activation of PTHrP-cyclic AMP (show TMPRSS5 Proteins)-CREB1 signaling following p53 (show TP53 Proteins) loss is essential for osteosarcoma initiation and maintenance.

  9. We propose that phosphorylation-dependent regulation of DNA binding activity evolved as a tunable mechanism to control CREB transcriptional output and promote metabolic homeostasis in response to rapidly changing environmental conditions.

  10. The present study provides the first critical in vivo evidence showing a causal link between epigenetic modification of miR (show MLXIP Proteins)-10a mediated by HDAC3 (show HDAC3 Proteins) and the development of diabetic nephropathy, and these results elucidate that HDAC3 (show HDAC3 Proteins)/miR (show MLXIP Proteins)-10a/CREB1 serves as a new mechanism underlying kidney injury, providing potential therapeutic targets in type 2 diabetes

Pig (Porcine) CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. The expression of porcine Prdx6 (show PRDX6 Proteins) gene is up-regulated by C/EBPbeta (show CEBPB Proteins) and CREB.

  2. Results suggest that cerebral hypoxia results in differential regulation of CREB protein-mediated expression of proapoptotic and antiapoptotic proteins in the cerebral cortex of newborn piglets.

Cow (Bovine) CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. Data indicate that Ser738/742-to-glutamate (show GRIN2A Proteins) protein kinase D (show PRKD1 Proteins) mutant increased AngII-induced CREB protein and activating transcription factor 2 (show ATF2 Proteins) phosphorylation, and phospho-CREB binding to the steroidogenic acute regulatory protein (show STAR Proteins) promoter.

  2. SUMO-1 has a role in modifying cAMP-response element-binding protein CREB in prolonged hypoxia.

  3. dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB phosphorylation mediated by calcium-independent phospholipase A2 (show LYPLA1 Proteins)

  4. the p38-MAPK (show MAPK14 Proteins)/CREB pathway plays a critical role in TNFalpha (show TNF Proteins)-induced VCAM-1 (show VCAM1 Proteins) expression

Xenopus laevis CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. We found several conserved cis elements in the frog CRF genes including a cAMP response element (CRE), activator protein 1 binding sites, and glucocorticoid response elements

  2. p38 MAPK (show MAPK14 Proteins) and CREB function along the dorsal-ventral axis in mesoderm patterning. The phosphorylated form of CREB (S133) is distributed in a gradient along the dorsal-ventral mesoderm axis and the p38 MAPK (show MAPK14 Proteins) pathway mediates the phosphorylation of CREB.

Zebrafish CAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

  1. modulating CREB activity during early zebrafish development caused significant defects in neural proliferation, midbrain-hindbrain organization and body patterning

CREB1 Protein Profile

Protein Summary

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Alternative names and synonyms associated with CREB1

  • cAMP responsive element binding protein 1 (CREB1)
  • cAMP responsive element binding protein 1 (creb1)
  • cAMP responsive element binding protein 1 (Creb1)
  • cAMP responsive element binding protein 1 (LOC100351999)
  • cAMP responsive element binding protein 1a (creb1a)
  • cyclic AMP response element binding protein (CREB)
  • 2310001E10Rik protein
  • 3526402H21Rik protein
  • AV083133 protein
  • Creb protein
  • Creb-1 protein
  • creb1 protein
  • zgc:55598 protein

Protein level used designations for CREB1

cAMP responsive element binding protein 1 , cAMP responsive element binding protein , cyclic AMP-responsive element-binding protein 1 , CREB-1 , active transcription factor CREB , cAMP-response element-binding protein-1 , cAMP-responsive element-binding protein 1 , transactivator protein , Y protein , cAMP response element binding protein 1 , cAMP response element-binding protein , cyclic AMP-responsive element binding protein, delta , cyclic AMP-responsive DNA-binding protein

100066388 Equus caballus
407934 Xenopus (Silurana) tropicalis
459901 Pan troglodytes
692871 Bombyx mori
708717 Macaca mulatta
751585 Taeniopygia guttata
100294619 Pongo abelii
100351999 Oryctolagus cuniculus
100542127 Meleagris gallopavo
100586647 Nomascus leucogenys
1385 Homo sapiens
12912 Mus musculus
81646 Rattus norvegicus
395099 Gallus gallus
607922 Canis lupus familiaris
397449 Sus scrofa
281713 Bos taurus
379764 Xenopus laevis
573207 Danio rerio
443118 Ovis aries
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