Browse our PKC delta Proteins (PKCd)

On www.antibodies-online.com are 25 Protein Kinase C, delta (PKCd) Proteins from 11 different suppliers available. Additionally we are shipping PKC delta Antibodies (293) and PKC delta Kits (49) and many more products for this protein. A total of 384 PKC delta products are currently listed.
Synonyms:
AI385711, D14Ertd420e, fb09d10, fv43b11, MAY1, nPKC-delta, Pkaca, PKC-delta, pkc-delta2, Pkcd, PKCdelta, PKC[d], PRKCD, tpa-1, wu:fb09d10, wu:fv43b11, zgc:56558
list all proteins Gene Name GeneID UniProt
PKCd 5580 Q05655
PKCd 18753 P28867
PKCd 170538 P09215

PKC delta Proteins (PKCd) by Origin

More Proteins for PKC delta Interaction Partners

Human Protein Kinase C, delta (PKCd) interaction partners

  1. PKCdelta is a critical regulator of signaling mechanisms of neutrophil-endothelium interaction in acute inflammation. Inhibition of PKCdelta in human endothelial cells and neutrophils reduced chemoattractant-induced neutrophil migration across TNF-alpha (show TNF Proteins)-activated endothelium, and reduced expression of E-selectin (show SELE Proteins) and ICAM-1 (show ICAM1 Proteins). Shear rate and vascular geometry regulate the impact of PKCdelta inhibition of neutrophil-endot...

  2. Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck (show HCK Proteins)-dependent activation of PKCdelta, which stimulates PKCgamma (show PRKCG Proteins), resulting in translocation of phosphorylated p47(phox).

  3. The interplay between intracellular progesterone receptor (show PGR Proteins) and PRKCA (show PKCa Proteins)-PRKCD plays a key role in migration and invasion of human glioblastoma cells.

  4. Amphiregulin (show AREG Proteins) enhances VEGF-A (show VEGFA Proteins) production in human chondrosarcoma cells and promotes angiogenesis by inhibiting miR (show MLXIP Proteins)-206 via FAK (show PTK2 Proteins)/c-Src (show SRC Proteins)/PKCdelta pathway.

  5. In the present investigation, we demonstrated that miR486 is negatively associated with the expression of PKC-delta and could regulate the development of osteosarcoma. miR (show MLXIP Proteins)-486 may be a potential target for the treatment of osteosarcoma

  6. PKCdelta and PKCepsilon (show PRKCE Proteins) work as a functional couple with opposite roles on thrombopoiesis, and the modulation of their balance strongly impacts platelet production.

  7. These findings suggest that targeting Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) or Akt (show AKT1 Proteins) pathways may increase the efficacy of taxane chemotherapy in advanced human prostate cancers that have lost PKCdelta expression.

  8. description of a rare monogenic form of juvenile systemic lupus erythematosus caused by a novel but damaging homozygous mutation affecting the active region of PRKCD.

  9. MALAT1 recruits splice factor serine-arginine-rich splice factor 2 (SRSF2 (show SRSF2 Proteins)) to promote alternative splicing of PKCdeltaII.

  10. mechanistic studies, inhibition of SRC (show SRC Proteins) and PKCdelta completely ablated the ability of MDA-7/IL-24 (show IL24 Proteins) to reduce the Bcl-x(L (show BCL2L1 Proteins))/(s) mRNA ratio and cell viability. These findings show that Bcl-x (show BCL2L1 Proteins)(s) expression is an important mediator of MDA-7/IL-24 (show IL24 Proteins)-induced cytotoxicity requiring the SRC (show SRC Proteins)/PKCdelta signaling axis in NSCLC cells.

Mouse (Murine) Protein Kinase C, delta (PKCd) interaction partners

  1. study identifies a new role of Dual-AKAP1 (show AKAP1 Proteins) in regulating mitochondrial trafficking through Miro-2 (show RHOT2 Proteins), and supports a model in which PINK1 (show PINK1 Proteins) and mitochondrial PKA participate in a similar neuroprotective signaling pathway to maintain dendrite connectivity

  2. Data suggest that enzyme activation by cAMP involves highly stable conformation of Prkar1a as it binds to Prkaca; glycine residue, G235, appears to function as hinge in B/C helix conserved in Prkar1a; this "Flipback" conformation plays role in cAMP association to A domain of Prkar1a. (Prkar1a = cyclic AMP-dependent protein kinase RIalpha subunit; Prkaca = cyclic AMP-dependent protein kinase catalytic subunit)

  3. K8/K18 (show KRT18 Proteins)-dependent PKCdelta- and ASMase (show SMPD1 Proteins)-mediated modulation of lipid raft size can explain the more prominent FasR-mediated signaling resulting from K8/K18 (show KRT18 Proteins) loss.

  4. MALAT1 recruits splice factor serine-arginine-rich splice factor 2 (SRSF2 (show SRSF2 Proteins)) to promote alternative splicing of PKCdeltaII.

  5. cAMP dependent protein kinase A (PKA) is a key intracellular factor mediating SHH (show SHH Proteins) signaling through regulation of GLI3 (show GLI3 Proteins) processing.

  6. this study shows illustrates for the first time the ability of protein kinase A to increase colony-stimulating factor 1 receptor (show CSF1R Proteins) DNA methylation (show HELLS Proteins) resulting in macrophage maturation

  7. these results suggest that the activation of 5-HT1D receptors selectively enhanced IA via the Gbetagamma of the Go-protein, PKA, and the sequential B-Raf (show SNRPE Proteins)-dependent p38 MAPK (show MAPK14 Proteins) signaling cascade.

  8. SphK1 (show SPHK1 Proteins) dependent PKC-delta activation plays an important role in promoting NF-kappaB (show NFKB1 Proteins) activation and inflammatory response in acute liver failure, and inhibition of PKC-delta activation might be a potential therapeutic strategy for this disease.

  9. PKCdelta activity exerts a dual role through the autophagy mechanism, decreasing proliferative capacity of mammary tumor cells but also regulating tumor stem cell self-renewal.

  10. alpha(1)-AR activation is anti-apoptotic and protective during cardiac ischemia due to glucose deprivation and not hypoxia by enhancing glucose uptake into the heart via PKCdelta-mediated GLUT (show SLC1A3 Proteins) translocation that may be specific to the alpha(1A)-AR subtype.

Cow (Bovine) Protein Kinase C, delta (PKCd) interaction partners

  1. Report PRKCD-dependent regulation of bovine embryonic development, gene expression and post-hatching events.

  2. investigation of signaling mechanism used by fibroblast growth factor-2 (FGF2 (show FGF2 Proteins)) to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 (show FGF2 Proteins) regulates IFNT production in trophoblasts by acting through PRKCD

  3. deltaPKC inhibition or varepsilonPKC activation repairs endothelial vascular dysfunction by regulating eNOS (show NOS3 Proteins) post-translational modification

  4. stimulation of bovine theca cells with lysophosphatidic acid leads to redistribution of protein kinase C delta from the cytosol to the perinuclear area and in the presence of LH, complete nuclear translocation of protein kinase C delta is induced

  5. Protein kinase (show CDK7 Proteins) Cdelta-dependent phosphorylation of syndecan-4 (show SDC4 Proteins) regulates cell migration.

Rabbit Protein Kinase C, delta (PKCd) interaction partners

  1. Activation of PKC induces the translocation of Nrf2 (show NFE2L2 Proteins) and the enhancement of endogenous antioxidant defenses in ischemic preconditioned rabbit heart.

  2. PKC-delta (show PRKCG Proteins) mediates the apoptotic processes through ROS (show ROS1 Proteins)-dependent caspase-3 (show CASP3 Proteins) activation

PKC delta (PKCd) Protein Profile

Protein Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with PKC delta (PKCd)

  • protein kinase C, delta a (prkcda)
  • protein kinase C, delta (prkcd-b)
  • protein kinase C, delta (prkcd)
  • protein kinase C, delta (LOC100230711)
  • protein kinase C, delta (PRKCD)
  • protein kinase C, delta (Prkcd)
  • protein kinase, cAMP dependent, catalytic, alpha (Prkaca)
  • AI385711 protein
  • D14Ertd420e protein
  • fb09d10 protein
  • fv43b11 protein
  • MAY1 protein
  • nPKC-delta protein
  • Pkaca protein
  • PKC-delta protein
  • pkc-delta2 protein
  • Pkcd protein
  • PKCdelta protein
  • PKC[d] protein
  • PRKCD protein
  • tpa-1 protein
  • wu:fb09d10 protein
  • wu:fv43b11 protein
  • zgc:56558 protein

Protein level used designations for Protein Kinase C, delta Proteins (PKCd)

protein kinase C delta type , protein kinase-delta2 , protein kinase C, delta , protein kinase C delta type-like , protein kinase C delta VIII , tyrosine-protein kinase PRKCD , nPKC-delta , protein kinase C delta variant IX , protein kinase C, delta IV , protein kinase C, delta V , protein kinase C[d] , protein kinase C delta , PKA C-alpha , cAMP-dependent protein kinase catalytic subunit alpha , sperm cAMP-dependent protein kinase catalytic subunit

GENE ID SPECIES
334571 Danio rerio
404227 Xenopus laevis
733756 Xenopus (Silurana) tropicalis
100230711 Taeniopygia guttata
100294651 Ovis aries
100395399 Callithrix jacchus
100452668 Pongo abelii
100591028 Nomascus leucogenys
5580 Homo sapiens
18753 Mus musculus
170538 Rattus norvegicus
505708 Bos taurus
100008966 Oryctolagus cuniculus
100126848 Sus scrofa
494005 Canis lupus familiaris
415905 Gallus gallus
101107639 Ovis aries
18747 Mus musculus
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