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Browse our PKC delta Proteins (PKCd)

Full name:
Protein Kinase C, delta Proteins (PKCd)
On are 21 Protein Kinase C, delta (PKCd) Proteins from 11 different suppliers available. Additionally we are shipping PKC delta Antibodies (278) and PKC delta Kits (52) and many more products for this protein. A total of 368 PKC delta products are currently listed.
AI385711, D14Ertd420e, fb09d10, fv43b11, MAY1, nPKC-delta, Pkaca, PKC-delta, pkc-delta2, Pkcd, PKCdelta, PKC[d], PRKCD, tpa-1, wu:fb09d10, wu:fv43b11, zgc:56558
list all proteins Gene Name GeneID UniProt
PKCd 5580 Q05655
PKCd 18753 P28867
PKCd 170538 P09215

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PKC delta Proteins (PKCd) by Origin

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Top referenced PKC delta Proteins

  1. Mouse (Murine) PKC delta Protein expressed in Baculovirus infected Insect Cells - ABIN2007697 : Benes, Wu, Elia, Dharia, Cantley, Soltoff: The C2 domain of PKCdelta is a phosphotyrosine binding domain. in Cell 2005 (PubMed)
    Show all 2 references for ABIN2007697

More Proteins for PKC delta Interaction Partners

Human Protein Kinase C, delta (PKCd) interaction partners

  1. PKCzeta (show PRKCZ Proteins) Promotes Breast Cancer Invasion by Regulating Expression of E-cadherin (show CDH1 Proteins) and Zonula Occludens-1 (ZO-1 (show TJP1 Proteins)) via NFkappaB (show NFKB1 Proteins)-p65 (show GORASP1 Proteins)

  2. Persistent PRKCD elevation in fibroblasts from diabetic patients inhibits insulin (show INS Proteins) signaling and function to impair wound healing.

  3. Data suggest that cytokines (TNF-alpha (show TNF Proteins), IL1-beta (show IL1B Proteins), IFN-gamma (show IFNG Proteins)) disrupt gap junction coupling in pancreatic islets under conditions associated with prediabetes; the mechanism appears to involve nitric oxide-mediated activation of protein kinase C-delta.

  4. Phosphorylation site at Ser130 adjacent to the pseudosubstrate domain contributes to the activation of protein kinase.

  5. Docosahexaenoic acid increase the efficacy of docetaxel in mammary cancer cells by downregulating Akt (show AKT1 Proteins) and PKCepsilon (show PRKCE Proteins)/delta-induced ERK (show EPHB2 Proteins) pathways.

  6. K-Ras (show HRAS Proteins) stabilization by estrogen via PKCdelta has a role in endometrial tumorigenesis

  7. PKC-delta is a crucial factor in the heat sensitivity and thermal resistance of tongue squamous carcinoma cells.

  8. Study shows selective phosphorylation of PKCdelta in HTLV1infected T cells where Tax (show CNTN2 Proteins) activates NFkappaB (show NFKB1 Proteins) through PKCdelta activation.

  9. Results show that PKCdelta acts as a critical regulator for the maintenance of tumor initiating cells in glioblastoma through specific phosphorylation on Ser473 of AKT (show AKT1 Proteins), therefore activating its signaling pathway.

  10. isotype delta-PKC (show PRRT2 Proteins) is responsible for myristoylated alanine-rich C-kinase substrate (MARCKS (show MARCKS Proteins)) phosphorylation in human neutrophils following f-Met-Leu-Phe stimulation and MARCKS (show MARCKS Proteins) phosphorylation is essential for neutrophil migration and adhesion.

Mouse (Murine) Protein Kinase C, delta (PKCd) interaction partners

  1. PKCdelta-mediated phosphorylation of 14-3-3zeta (show YWHAZ Proteins) contributes to the nuclear retention of FOXO1 (show FOXO1 Proteins), even when FOXO1 (show FOXO1 Proteins) is phosphorylated as under non-stress conditions

  2. The homozygous Prkcqrpea1 and the null Prkcqtm1Litt mutants are reliable novel mouse models of RD and can also be used to study the effects of the disruption of PRKCQ (PKCtheta (show PRKCQ Proteins);) signaling in RPE (show RPE Proteins) cells.

  3. function of protein kinase C delta (PKCdelta) during fertilization and embryonic development

  4. A novel PKCdelta signaling pathway that requires retinol as a metabolic cofactor.

  5. PKA phosphorylates the ATPase inhibitory factor 1 (show ATPIF1 Proteins) and inactivates its capacity to bind and inhibit the mitochondrial H(+)-ATP synthase.

  6. Data suggest that cytokines (TNF-alpha (show TNF Proteins), IL1-beta (show IL1B Proteins), IFN-gamma (show IFNG Proteins)) disrupt gap junction coupling in pancreatic islets under conditions associated with prediabetes; the mechanism appears to involve nitric oxide-mediated activation of protein kinase C-delta.

  7. PKCdelta acts as a proapototic kinase in oxidized phospholipid-included apoptosis of RAW 264.7 macrophages.

  8. Data suggest PRKAR1A (show PRKAR1A Proteins) contains two structurally homologous cAMP-binding domains that exhibit marked differences in dynamic profiles in activation/inhibition of Prkaca (show PRKACA Proteins); conservation of structure does not necessarily imply conservation of dynamics.

  9. Data show that protein kinase C delta (PKC-delta) knockout mice display atypical structural alterations at the articular cartilage and bone-cartilage interface.

  10. Data (including data from studies in transgenic mice) suggest that constitutive activation of Prkaca (show PRKACA Proteins) in osteoblasts is sufficient to increase bone mass, favorably modify bone architecture, and improve mechanical properties of bone.

Cow (Bovine) Protein Kinase C, delta (PKCd) interaction partners

  1. investigation of signaling mechanism used by fibroblast growth factor-2 (FGF2 (show FGF2 Proteins)) to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 (show FGF2 Proteins) regulates IFNT production in trophoblasts by acting through PRKCD

  2. deltaPKC inhibition or varepsilonPKC activation repairs endothelial vascular dysfunction by regulating eNOS (show NOS3 Proteins) post-translational modification

  3. stimulation of bovine theca cells with lysophosphatidic acid leads to redistribution of protein kinase C delta from the cytosol to the perinuclear area and in the presence of LH, complete nuclear translocation of protein kinase C delta is induced

  4. Protein kinase (show CDK7 Proteins) Cdelta-dependent phosphorylation of syndecan-4 (show SDC4 Proteins) regulates cell migration.

Rabbit Protein Kinase C, delta (PKCd) interaction partners

  1. Activation of PKC induces the translocation of Nrf2 (show NFE2L2 Proteins) and the enhancement of endogenous antioxidant defenses in ischemic preconditioned rabbit heart.

  2. PKC-delta (show PRKCG Proteins) mediates the apoptotic processes through ROS (show ROS1 Proteins)-dependent caspase-3 (show CASP3 Proteins) activation

Pig (Porcine) Protein Kinase C, delta (PKCd) interaction partners

  1. Anti-proliferative/pro-apoptotic effects of testosterone on coronary artery smooth cells are mediated by protein kinase C-delta.

PKC delta (PKCd) Protein Profile

Protein Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with PKC delta (PKCd)

  • protein kinase C, delta a (prkcda)
  • protein kinase C, delta (prkcd-b)
  • protein kinase C, delta (prkcd)
  • protein kinase C, delta (LOC100230711)
  • protein kinase C, delta (PRKCD)
  • protein kinase C, delta (Prkcd)
  • protein kinase, cAMP dependent, catalytic, alpha (Prkaca)
  • AI385711 protein
  • D14Ertd420e protein
  • fb09d10 protein
  • fv43b11 protein
  • MAY1 protein
  • nPKC-delta protein
  • Pkaca protein
  • PKC-delta protein
  • pkc-delta2 protein
  • Pkcd protein
  • PKCdelta protein
  • PKC[d] protein
  • PRKCD protein
  • tpa-1 protein
  • wu:fb09d10 protein
  • wu:fv43b11 protein
  • zgc:56558 protein

Protein level used designations for Protein Kinase C, delta Proteins (PKCd)

protein kinase C delta type , protein kinase-delta2 , protein kinase C, delta , protein kinase C delta type-like , protein kinase C delta VIII , tyrosine-protein kinase PRKCD , nPKC-delta , protein kinase C delta variant IX , protein kinase C, delta IV , protein kinase C, delta V , protein kinase C[d] , protein kinase C delta , PKA C-alpha , cAMP-dependent protein kinase catalytic subunit alpha , sperm cAMP-dependent protein kinase catalytic subunit

334571 Danio rerio
404227 Xenopus laevis
733756 Xenopus (Silurana) tropicalis
100230711 Taeniopygia guttata
100294651 Ovis aries
100395399 Callithrix jacchus
100452668 Pongo abelii
100591028 Nomascus leucogenys
5580 Homo sapiens
18753 Mus musculus
170538 Rattus norvegicus
505708 Bos taurus
100008966 Oryctolagus cuniculus
100126848 Sus scrofa
494005 Canis lupus familiaris
415905 Gallus gallus
101107639 Ovis aries
18747 Mus musculus
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